peptidoglycan

Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a high protective activity on cell damag

Muramic acid HCl is part of the peptidoglycan in the cell wall of many Gram-positive bacteria.

Vancomycin hydrochloride (Vancomycin HCl) is a glycopeptide antibiotic that targets Peptidoglycan in bacterial cell wall synthesis. Vancomycin hydrochloride is mainly used for the treatment of severe Gram-positive bacterial infections.

Bacitracin (Ziba-RX), a mixture of related cyclic polypeptides, disrupts bacteria by interfering with cell wall and peptidoglycan synthesis.

D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.

Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram negative bacteria and is the attachment point for Braun's lipoprotein (BLP or Murein Lipoprotein). BLP is found in gram-negative cell walls and is one of the most abundant membrane proteins. BLP is bound at its C-terminal end (a lysine) by a covalent bond to the peptidoglycan layer (specifically to diaminopimelic acid molecules) and is embedded in the outer membrane by its hydrophobic head (a cysteine with lipids attached). BLP tightly links the two layers and provides structural integrity to the bacterial outer membrane. Diaminopimelic acid can be found in human urine or feces due to the lysis or enzymatic breakdown of gram negative gut microbes.

Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.

Ac-muramic acid (MurNAc) is an essential component of bacterial peptidoglycan, the structural polymer of the cell wall. Ac-muramic acid is covalently linked to N-acetylglucosamine through β-1,4 linkages and may also be connected via the hydroxyl group on carbon-4 to the carbon atom of L-alanine, forming part of the peptide stem. MurNAc is central to bacterial cell wall biosynthesis studies.

Bacitracin (Standard) is the standard substance of Bacitracin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Bacitracin (Ziba-RX), a mixture of related cyclic polypeptides, disrupts bacteria by interfering with cell wall and peptidoglycan synthesis.

Vancomycin hydrochloride (Standard) is the standard substance of Vancomycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Vancomycin hydrochloride (Vancomycin HCl) is a glycopeptide antibiotic that targets Peptidoglycan in bacterial cell wall synthesis. Vancomycin hydrochloride is mainly used for the treatment of severe Gram-positive bacterial infections.

Malioxamycin is an antibiotic that inhibits Gram-negative bacteria by suppressing peptidoglycan synthesis in the bacterial cell wall and promoting the formation of protoplasts.

Friulimicin C is a lipopeptide antibiotic known for its activity in inhibiting peptidoglycan synthesis.

α-D-Glucosamine 1-phosphate, an E. coli metabolite, is a precursor in peptidoglycan synthesis [1] [2].

Meso-2,6-diaminopimelic acid is an essential precursor in the biosynthesis of the amino acid L-lysine and a critical component of peptidoglycan in the cell walls of various bacteria.