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Search Result

Search Results for " efflux "

86

Compounds

19

Natural Products

26

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T72521 Efflux inhibitor-1
Efflux inhibitor-1 is a pyrazolopyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC 50 s of 0.45 μM and 2.17 μM, respectively .
T8596 Ceefourin 1 MRP
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
T1050 Prazosin hydrochloride Prazosin hydrochloride,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,Minipress Potassium Channel , MRP , Adrenergic Receptor , ABC , Autophagy
Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin hydrochloride is a synthetic ...
T16339 Norverapamil hydrochloride (±)-Norverapamil hydrochloride,D591 hydrochloride Calcium Channel , P-gp , Drug Metabolite
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
T12374 PAβN dihydrochloride MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride Others , Antibacterial
PAβN dihydrochloride (MC-207,110 dihydrochloride) is an inhibitor of efflux pump.
T16744 Rhodamine 6G Basic Red 1 Others
Rhodamine 6G (Basic Red 1) is a rhodamine analog useful in Pgp efflux assays. It can be widely used in characterizing the kinetics of MRP1- mediated efflux as a laser dye and potential mitochondrial probe.
T14076 A 839977 A839977,A-839977 P2X Receptor , Calcium Channel
A 839977 is a selective P2X7 receptor antagonist with anti-inflammatory and analgesic activity that inhibits BzATP-induced calcium efflux from the P2X7 receptor for the study of renal fibrosis.
T24542 NP-313 NP 313,NSC 4264,NSC-4264,NSC4264
NP-313 (NSC-4264) is a potent antithrombotic agent that inhibits platelet aggregation and activation by inhibiting thromboxane A 2 synthesis and selectively inhibiting SOCC-mediated Ca2+ efflux.
T9587 CCTA-1523 Others , ABC
CCTA-1523 is an efflux function of ABCG2 inhibitor. CCTA-1523 selectively reverses ABCG2-mediated MDR in cancer cells.
T16349 NSC-60339 Others , Antibacterial
NSC-60339 is an inhibitor of efflux pump, and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent.
T24170 Iodoantipyrine Jodantipyrine,EINECS 204-966-6,Arthripur,Iodophenazone Others
Iodoantipyrine (Arthripur) is a commonly-used indicator and is used to evaluate in rats by measuring torcular venous efflux after systemic injection of the indicator under conditions of normal and high CBF.
T4497 Amifampridine 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine Others
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...
T19649 PF-06273340 PF 6273340,PF 06273340,PF6273340,PF-6273340 Trk receptor
PF-06273340 is an effective, Selective, and Peripherally Restricted Pan-Trk inhibitor (IC50: Trk-A = 6 nM; Trk-B = 4 nM; Trk-C = 3 nM). PF-06273340 has low metabolic turnover in HLM and hHep is a good substrate for efflu...
T29645 Adatanserin hydrochloride WY50324 hydrochloride 5-HT Receptor
Adatanserin hydrochloride (WY50324 hydrochloride) is a novel 5-HT(1A)/5-HT(2) receptor ligand with potential neuroprotective effects and inhibition of ischemic efflux of endogenous amino acids, which can be used in the s...
T12343 Benzquinamide BZQ,P2647,Benzoquinamide Adrenergic Receptor
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzqui...
T0939 Phenytoin Diphenylhydantoin,5,5-Diphenylhydantoin Virus Protease , Sodium Channel
Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cor...
T60165 VB124 Monocarboxylate transporter
VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for lactate import and export, respectively, in MDA-MB-231 cell...
T1433 Ritodrine hydrochloride DU21220,Ritodrine HCl,NSC 291565 Adrenergic Receptor
Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NS...
T1146 Nifedipine BAY-a-1040,Procardia XL,Procardia,Adalat CaMK , Potassium Channel , Calcium Channel , Autophagy
Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation ...
T3148 MK-571 sodium L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid Leukotriene Receptor , LTR
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the ...
T74827 AcrB-IN-2
Efflux pump-IN-2 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics . Efflux pump-IN-2 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-2 does not disrupts the bact...
T27609 INF55
INF55 inhibits NorA efflux pump.
T28808 SLUPP-417 SLUPP417
SLUPP-417 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
T24434 MCC1189 MCC 1189,MCC-1189
MCC1189 is a first-in-class MFS efflux pump CaMdr1p inhibitor.
T28807 SLUPP-225 SLUPP 225
SLUPP-225 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
T10944 D13-9001 Others
The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-Op...
T29428 4010B-30 4010B30
4010B-30 is an up-regulation of apolipoprotein A-I gene expression. It functions by promoting cholesterol efflux, ABCA1 expression, and PPAR activation.
T74829 AcrB-IN-4
Efflux pump-IN-4, an AcrB efflux pump inhibitor, potentiate[s] the effects of antibiotics by inhibiting the efflux of Nile Red (a known substrate of AcrB). It does not disrupt the bacterial outer membrane or display toxi...
T10490 (S)-ML753286 Others
(S)-ML753286 is a breast cancer resistance protein (BCRP) inhibitor (IC50: 0.6 μM on BCRP efflux transporter).
T74828 AcrB-IN-3
Efflux pump-IN-3, an AcrB efflux pump inhibitor, potentiates the effect of antibiotics by inhibiting the efflux of Nile Red (a known substrate of AcrB). It does not disrupt the bacterial outer membrane or exhibit toxicit...
T81654 NorA-IN-1
NorA-IN-1 (Compound 16), a NorA efflux pump inhibitor, has applications in the research of multidrug resistance [1]. It functions by impeding the NorA efflux pump in everted membrane vesicles.
T24005 DJ101 DJ-101,DJ 101
DJ101is an effective and metabolically stable inhibitor of tubulin. It can circumvent the drug efflux pumps responsible for multidrug resistance of existing tubulin inhibitors.
T26911 Bromotetrandrine 5-Bromotetrandrine,W-198,BrTet,W 198,W198
Bromotetrandrine is an P-glycoprotein inhibitor, which were developed and coadministered with chemotherapeutic drugs to overcome the effect of efflux pumps thus enhancing the chemosensitivity of therapeutics.
T71735 AAL1
AAL1 is an inhibitor of dark-grown Arabidopsis thaliana seedlings, functioning through auxin receptor Transport Inhibitor Response1 (TIR1) and depending on auxin influx and efflux carriers.
T40898 DMHCA
DMHCA, a potent, selective LXR agonist, specifically activates the LXR pathway's cholesterol efflux arm, avoiding triglyceride synthesis stimulation. This compound exhibits anti-inflammatory properties and is utilized in...
T14915 CDK12-IN-E9 CDK
CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux. It has a weak binding ability to CDK7/CyclinH complex (IC50> 1 μM).
T69976 WS-691
WS-691 is a highly Potent and Orally Active ABCB1 Modulator. WS-691 significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC50 = 22.02 nM). WS-691 significantly increased the...
T63267 P-gp/BCRP-IN-1
P-gp/BCRP-IN-1 (compound 19) is a relatively safe, orally active, and efficient inhibitor of the efflux transporters P-gp and BCRP. By inhibiting their efflux function, it reverses resistance and enhances the oral bioava...
T69317 Dexverapamil
Dexverapamil is the R-enantiomer of the calcium channel blocker verapamil. Dexverapamil competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1), thereby potentially increasing the effectiveness...
T82723 ChTX-Lq2
Charybdotoxin-Lq2 (ChTX-Lq2) is a potent inhibitor of calcium-activated potassium efflux, exhibiting a dissociation constant (Kd) of 43 nanomolar (nM) [1].
T12106 MRL-494 Others
MRL-494 is an antibacterial agent and is a small-molecule inhibitor of β-barrel assembly machine A (BamA) impervious to efflux and the outer membrane permeability barrier.
T80047 Polistes mastoparan
Polistes mastoparan, an antimicrobial peptide, enhances K+ efflux in S. aureus cells and reduces cell viability, exhibiting an EC50 of 5 μM [1].
T25356 E17110 E-17110,E 17110
E17110 is an LXRβ agonist. E17110 exhibited a significant activation effect on LXRβ (EC50: 0.72 μmol/L). E17110 also increased the expression of ABCA1 and ABCG1 in RAW264.7 macrophages. E17110 significantly decreased cel...
T35927 C2 L-threo Ceramide (d18:1/2:0) C2 L-threo Ceramide (d18:1/2:0)
C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration o...
T32242 IWP-051 IWP051
IWP-051 is a potent, orally active sGC stimulator (EC50 = 290nM). IWP-051 showed >99% plasma protein binding, high metabolic stability, high permeability, and no efflux in a Caco-2 model of intestinal absorption. IWP-...
T61504 PKM2 activator 3
PKM2 activator 3 is a highly potent compound that activates PKM2, with an AC 50 value of 90 nM. It exhibits excellent Caco-2 permeability, a low efflux ratio, and remarkable microsomal stability. PKM2 activator 3 is part...
T37296 GI-530159
TREK1 and TREK2 channel activator (EC50 = 0.76 μM in Rb efflux assay in TREK1-expressing CHO cells). Exhibits selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Hyperpolarizes membrane pot...
T69139 Thalicarpine
Thalicarpine is a natural aporphine benzylisoquinoline vinca alkaloid with antineoplastic activity. Thalicarpine binds to and inhibits p-glycoprotein, the multidrug resistance efflux pump. Thalicarpine also induces singl...
T28648 S39625 S-39625,S 39625
S39625, an E-ring camptothecin keto analogue, is a stable, potent, and selective topoisomerase I inhibitor without being substrates of drug efflux transporters. Nanomolar concentrations of S39625 induces intense and pers...
T13222 TTT-28 Others
TTT-28 is a thiazole-valine peptidomimetic, and is a selective ABCB1 (P-gp/MDR1) inhibitor with high efficacy and low toxicity, which reverses the ATP-binding cassette sub-family B member 1 (ABCB1)-mediated Multidrug res...

Compounds

Efflux inhibitor-1
T72521
Synonym:
Target:
Ceefourin 1
T8596
Synonym:
Target: MRP
Prazosin hydrochloride
T1050
Synonym: Prazosin hydrochloride,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,Minipress
Target: Potassium Channel, MRP, Adrenergic Receptor, ABC, Autophagy
Norverapamil hydrochloride
T16339
Synonym: (±)-Norverapamil hydrochloride,D591 hydrochloride
Target: Calcium Channel, P-gp, Drug Metabolite
PAβN dihydrochloride
T12374
Synonym: MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride
Target: Others, Antibacterial
Rhodamine 6G
T16744
Synonym: Basic Red 1
Target: Others
A 839977
T14076
Synonym: A839977,A-839977
Target: P2X Receptor, Calcium Channel
NP-313
T24542
Synonym: NP 313,NSC 4264,NSC-4264,NSC4264
Target:
CCTA-1523
T9587
Synonym:
Target: Others, ABC
NSC-60339
T16349
Synonym:
Target: Others, Antibacterial
Iodoantipyrine
T24170
Synonym: Jodantipyrine,EINECS 204-966-6,Arthripur,Iodophenazone
Target: Others
Amifampridine
T4497
Synonym: 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine
Target: Others
PF-06273340
T19649
Synonym: PF 6273340,PF 06273340,PF6273340,PF-6273340
Target: Trk receptor
Adatanserin hydrochloride
T29645
Synonym: WY50324 hydrochloride
Target: 5-HT Receptor
Benzquinamide
T12343
Synonym: BZQ,P2647,Benzoquinamide
Target: Adrenergic Receptor
Phenytoin
T0939
Synonym: Diphenylhydantoin,5,5-Diphenylhydantoin
Target: Virus Protease, Sodium Channel
VB124
T60165
Synonym:
Target: Monocarboxylate transporter
Ritodrine hydrochloride
T1433
Synonym: DU21220,Ritodrine HCl,NSC 291565
Target: Adrenergic Receptor
Nifedipine
T1146
Synonym: BAY-a-1040,Procardia XL,Procardia,Adalat
Target: CaMK, Potassium Channel, Calcium Channel, Autophagy
MK-571 sodium
T3148
Synonym: L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid
Target: Leukotriene Receptor, LTR
AcrB-IN-2
T74827
Synonym:
Target:
INF55
T27609
Synonym:
Target:
SLUPP-417
T28808
Synonym: SLUPP417
Target:
MCC1189
T24434
Synonym: MCC 1189,MCC-1189
Target:
SLUPP-225
T28807
Synonym: SLUPP 225
Target:
D13-9001
T10944
Synonym:
Target: Others
4010B-30
T29428
Synonym: 4010B30
Target:
AcrB-IN-4
T74829
Synonym:
Target:
(S)-ML753286
T10490
Synonym:
Target: Others
AcrB-IN-3
T74828
Synonym:
Target:
NorA-IN-1
T81654
Synonym:
Target:
DJ101
T24005
Synonym: DJ-101,DJ 101
Target:
Bromotetrandrine
T26911
Synonym: 5-Bromotetrandrine,W-198,BrTet,W 198,W198
Target:
AAL1
T71735
Synonym:
Target:
DMHCA
T40898
Synonym:
Target:
CDK12-IN-E9
T14915
Synonym:
Target: CDK
WS-691
T69976
Synonym:
Target:
P-gp/BCRP-IN-1
T63267
Synonym:
Target:
Dexverapamil
T69317
Synonym:
Target:
ChTX-Lq2
T82723
Synonym:
Target:
MRL-494
T12106
Synonym:
Target: Others
Polistes mastoparan
T80047
Synonym:
Target:
E17110
T25356
Synonym: E-17110,E 17110
Target:
C2 L-threo Ceramide (d18:1/2:0)
T35927
Synonym: C2 L-threo Ceramide (d18:1/2:0)
Target:
IWP-051
T32242
Synonym: IWP051
Target:
PKM2 activator 3
T61504
Synonym:
Target:
GI-530159
T37296
Synonym:
Target:
Thalicarpine
T69139
Synonym:
Target:
S39625
T28648
Synonym: S-39625,S 39625
Target:
TTT-28
T13222
Synonym:
Target: Others
1 2
Cat No. Product Name Synonyms Targets
T5S0246 Pseudoprotodioscin Others , Fatty Acid Synthase
1. Pseudoprotodioscin has moderate cytotoxicity.
T19768 γ-Tocotrienol gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol Others
γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E. Itl is also a radioprotector, antioxidant. It shows antitumor and antihypertensive effects in vivo.
TN3150 6,8-Diprenylnaringenin Senegalensin,Lonchocarpol A BCRP , ABC
6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus. 6,8-Diprenylnaringenin is a breast cancer resistance protein(BCRP) inhibitor with some estrogenicity.
T4818 Thyminose 2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose Others , Endogenous Metabolite
Thyminose (2-Deoxy-D-arabinose) induces Apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
TN1493 Chrysosplenol D IL Receptor , NF-κB , JNK
Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.
T8165 Erythrodiol Endogenous Metabolite , ABC
Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.
T19554 L-Aspartic aicd sodium L-Aspartic acid sodium,Sodium L-aspartate Others , Sodium Channel , Endogenous Metabolite
L-Aspartic aicd sodium (Sodium L-aspartate) is an amino acid, a precursor active molecule for colon-specific active molecule delivery, that promotes Na+ efflux from rat forebrain membrane vesicles.
T6S0095 Genkwanin 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether Virus Protease
1. Genkwanin (Apigenin 7-methyl ether) exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance pr...
TMA2270 Alisol F 24-acetate P-gp
Alisol F 24-acetate is a natural product isolated from Alisma plantago-aquatica Linn[1]. Alisol F 24 Acetate enhances chemosensitivity and apoptosis of MCF-7/DOX Cells by inhibiting P-Glycoprotein-Mediated drug efflux[2]...
T14140 Agaric acid Agaricinic Acid Mitochondrial Metabolism , AChR
Agaricic acid is an adenine nucleotide translocase antagonist.It is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid (Agaricinic Acid) induces mitochondri...
T6S0653 Linarin Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine TNF , AChE
1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...
TN5466 Boeravinone B
Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for fur...
TN1462 Cajanin ERK , MEK , Akt
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose up...
T79992 Sarglaroids F Caspase
Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+ efflux and diminishing Caspase-1(P20) concentrations. Additional...
T82339 Gangliotetraose Gg4
Gangliotetraose (Gg4), a tetrasccharide, predominantly comprises GM1 and its sialylated derivatives, which play a crucial role in modulating nuclear Ca2+ efflux and maintaining lower nuclear Ca2+ levels in differentiated...
T80001 Majoranaquinone Antibiotic
Majoranaquinone demonstrates potent antibacterial activity against four Staphylococcus strains, one Moraxella strain, and one Enterococcus strain. It also acts as an effective efflux pump inhibitor in Escherichia coli AT...
TN2160 Roemerine (-)-Roemerine Antibiotic
Roemerine ((-)-Roemerine) is a porphyrin alkaloid from Senegalese lychee with antifungal and anticancer activity that prevents berberine efflux through inhibition of Bmr. Roemerine increases cell membrane permeability in...
TN5530 Volkensiflavone Talbotaflavone Others
Volkensiflavone (Talbotaflavone) is a natural product found in astragalus and garcinia. It has the function of plant metabolite, is a secondary metabolic product. Volkensiflavone is a biflavonoid belonging to the hydroxy...
TN5474 Bonducellin
Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bon...

Natural Products

Pseudoprotodioscin
T5S0246
Synonym:
Target: Others, Fatty Acid Synthase
γ-Tocotrienol
T19768
Synonym: gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol
Target: Others
6,8-Diprenylnaringenin
TN3150
Synonym: Senegalensin,Lonchocarpol A
Target: BCRP, ABC
Thyminose
T4818
Synonym: 2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose
Target: Others, Endogenous Metabolite
Chrysosplenol D
TN1493
Synonym:
Target: IL Receptor, NF-κB, JNK
Erythrodiol
T8165
Synonym:
Target: Endogenous Metabolite, ABC
L-Aspartic aicd sodium
T19554
Synonym: L-Aspartic acid sodium,Sodium L-aspartate
Target: Others, Sodium Channel, Endogenous Metabolite
Genkwanin
T6S0095
Synonym: 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether
Target: Virus Protease
Alisol F 24-acetate
TMA2270
Synonym:
Target: P-gp
Agaric acid
T14140
Synonym: Agaricinic Acid
Target: Mitochondrial Metabolism, AChR
Linarin
T6S0653
Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine
Target: TNF, AChE
Boeravinone B
TN5466
Synonym:
Target:
Cajanin
TN1462
Synonym:
Target: ERK, MEK, Akt
Sarglaroids F
T79992
Synonym:
Target: Caspase
Gangliotetraose
T82339
Synonym: Gg4
Target:
Majoranaquinone
T80001
Synonym:
Target: Antibiotic
Roemerine
TN2160
Synonym: (-)-Roemerine
Target: Antibiotic
Volkensiflavone
TN5530
Synonym: Talbotaflavone
Target: Others
Bonducellin
TN5474
Synonym:
Target:

Recombinant Proteins

Species：
Human (13)
Mouse (6)
Bovine (2)
Cynomolgus (1)
Mycobacterium tuberculosis (1)
Plasmodium falciparum (1)
Raphanus sativus (1)
Rat (1)
Expression System：
E. coli (15)
HEK293 (8)
in vitro E. coli expression system (2)
Yeast (1)
Tag：
His (7)
C-His (3)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (3)
N-terminal 6xHis-tagged (3)
hFc (3)
N-terminal 10xHis-tagged (2)
N-terminal 6xHis-SUMO-tagged (2)
N-terminal 6xHis-GST-tagged (1)
None (1)
Tag-Free (1)
Cat No. Product Name Species Expression System
TMPY-02899 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His) Mouse HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-00915 Serpin A1 Protein, Human, Recombinant (His) Human HEK293
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit...
TMPH-03139 MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) Plasmodium falciparum E. coli
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
TMPK-01291 ANXA1 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPK-00799 ANXA1 Protein, Mouse, Recombinant (His) Mouse E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPH-03231 AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) Raphanus sativus E. coli
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake.
TMPH-02316 YJEFN3 Protein, Human, Recombinant Human E. coli
May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endotheli...
TMPK-00768 ANXA1 Protein, Human, Recombinant (His) Human E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPH-02979 SLC30A8 Protein, Mouse, Recombinant (His) Mouse in vitro E. coli expression system
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-...
TMPH-02323 SLC30A8 Protein, Human, Recombinant (His) Human in vitro E. coli expression system
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-...
TMPH-00225 APOA1 Protein, Bovine, Recombinant (His) Bovine Yeast
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). A...
TMPH-00224 APOA1 Protein, Bovine, Recombinant (E. coli, His) Bovine E. coli
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). A...
TMPH-02409 LprG Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) Mycobacterium tuberculosis E. coli
Probably helps membrane protein MT1454 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membrane. TAG probably regulates lipid metabolism and ...
TMPY-02209 CUTC Protein, Human, Recombinant (His) Human E. coli
Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+per subunit. ...
TMPJ-00158 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant Human E. coli
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various...
TMPH-02322 SLC30A10 Protein, Human, Recombinant (His & Myc) Human E. coli
Plays a pivotal role in manganese transport. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic p...
TMPY-03428 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (His) Human E. coli
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-06955 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-02553 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc) Mouse HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-00667 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (hFc) Human HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPH-02959 Tsukushi Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Contributes to various developmental events and other processes such as wound healing and cholesterol homeostasis through its interactions with multiple signaling pathways. Wnt signaling inhibitor which competes with WNT...
TMPY-01858 PLTP Protein, Human, Recombinant (His) Human HEK293
Phospholipid transfer protein, also known as Lipid transfer protein II and PLTP, is a secreted protein that belongs to the BPI/LBP/Plunc superfamily and BPI / LBP family. PLTP is nearly ubiquitously expressed in cells an...
TMPY-06100 PLTP Protein, Human, Recombinant (His), Biotinylated Human HEK293
Phospholipid transfer protein, also known as Lipid transfer protein II and PLTP, is a secreted protein that belongs to the BPI/LBP/Plunc superfamily and BPI / LBP family. PLTP is nearly ubiquitously expressed in cells an...
TMPH-01739 NLRP3 Protein, Human, Recombinant (His) Human E. coli
As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polym...
TMPY-00442 Serpin A1 Protein, Rat, Recombinant (His) Rat HEK293
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit...
TMPH-01364 Galectin-9/LGALS9 Protein, Human, Recombinant (GST & His) Human E. coli
Binds galactosides. Has high affinity for the Forssman pentasaccharide. Ligand for HAVCR2/TIM3. Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death. Also stimulates bactericidal activity in infected macropha...
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His)
TMPY-02899
Species: Mouse
Expression System: HEK293
Serpin A1 Protein, Human, Recombinant (His)
TMPY-00915
Species: Human
Expression System: HEK293
MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO)
TMPH-03139
Species: Plasmodium falciparum
Expression System: E. coli
ANXA1 Protein, Cynomolgus, Recombinant (His)
TMPK-01291
Species: Cynomolgus
Expression System: E. coli
ANXA1 Protein, Mouse, Recombinant (His)
TMPK-00799
Species: Mouse
Expression System: E. coli
AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)
TMPH-03231
Species: Raphanus sativus
Expression System: E. coli
YJEFN3 Protein, Human, Recombinant
TMPH-02316
Species: Human
Expression System: E. coli
ANXA1 Protein, Human, Recombinant (His)
TMPK-00768
Species: Human
Expression System: E. coli
SLC30A8 Protein, Mouse, Recombinant (His)
TMPH-02979
Species: Mouse
Expression System: in vitro E. coli expression system
SLC30A8 Protein, Human, Recombinant (His)
TMPH-02323
Species: Human
Expression System: in vitro E. coli expression system
APOA1 Protein, Bovine, Recombinant (His)
TMPH-00225
Species: Bovine
Expression System: Yeast
APOA1 Protein, Bovine, Recombinant (E. coli, His)
TMPH-00224
Species: Bovine
Expression System: E. coli
LprG Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
TMPH-02409
Species: Mycobacterium tuberculosis
Expression System: E. coli
CUTC Protein, Human, Recombinant (His)
TMPY-02209
Species: Human
Expression System: E. coli
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant
TMPJ-00158
Species: Human
Expression System: E. coli
SLC30A10 Protein, Human, Recombinant (His & Myc)
TMPH-02322
Species: Human
Expression System: E. coli
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (His)
TMPY-03428
Species: Human
Expression System: E. coli
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc)
TMPY-06955
Species: Mouse
Expression System: HEK293
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc)
TMPY-02553
Species: Mouse
Expression System: HEK293
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (hFc)
TMPY-00667
Species: Human
Expression System: HEK293
Tsukushi Protein, Mouse, Recombinant (His & Myc)
TMPH-02959
Species: Mouse
Expression System: E. coli
PLTP Protein, Human, Recombinant (His)
TMPY-01858
Species: Human
Expression System: HEK293
PLTP Protein, Human, Recombinant (His), Biotinylated
TMPY-06100
Species: Human
Expression System: HEK293
NLRP3 Protein, Human, Recombinant (His)
TMPH-01739
Species: Human
Expression System: E. coli
Serpin A1 Protein, Rat, Recombinant (His)
TMPY-00442
Species: Rat
Expression System: HEK293
Galectin-9/LGALS9 Protein, Human, Recombinant (GST & His)
TMPH-01364
Species: Human
Expression System: E. coli
Cat No. Product Name
L7300 Potassium Channel Blocker Library

160 compounds
A unique collection of 160 potassium channel blockers and agonists for high throughput and high content screening;

Libraries

Potassium Channel Blocker Library
L7300
Compounds: 160
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