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Evinacumab
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Catalog No. T77492Cas No. 1446419-85-7
Alias REGN1500, REGN 1500
Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.
Evinacumab
Evinacumab
😃Good
Catalog No. T77492Alias REGN1500, REGN 1500Cas No. 1446419-85-7
Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $372 | - | In Stock | |
| 5 mg | $993 | - | In Stock | |
| 10 mg | $1,330 | - | In Stock | |
| 25 mg | $1,980 | - | In Stock | |
| 50 mg | $2,680 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:100% (SEC-HPLC)
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| Description | Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases. |
| In vitro | Evinacumab has similar affinity for ANGPTL3 in human, mouse, rat and monkey with KD = 0.26-1.28 nM. [1] |
| In vivo | Evinacumab (10 mg/kg intrperitoneally administered once weekly for 8 weeks) reduced serum TGs in C57Bl/6 mice with normal lipemia. After Evinacumab treatment, heparin LPL activity increased 1.8 times in C57Bl/6 mice and 2.5 times in db/db mice. Evinacumab (3 mg/kg or 10 mg/kg) reduced blood lipids in cynomolgus monkeys. [1] |
| Synonyms | REGN1500, REGN 1500 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | ANGPTL3 |
| Molecular Weight | 150 kDa |
| Cas No. | 1446419-85-7 |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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