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Evinacumab
(Synonyms: REGN1500, REGN 1500) Copy Product Info
🥰Excellent
Synonyms: REGN1500, REGN 1500
Catalog No. T77492 Copy Product Info
🥰Excellent
Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.
Cas No. 1446419-85-7
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $372 | - | In Stock | |
| 5 mg | $993 | - | In Stock | |
| 10 mg | $1,330 | - | In Stock | |
| 25 mg | $1,980 | - | In Stock | |
| 50 mg | $2,680 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases. |
| In vitro | Evinacumab has similar affinity for ANGPTL3 in human, mouse, rat and monkey with KD = 0.26-1.28 nM. [1] |
| In vivo | Evinacumab (10 mg/kg intrperitoneally administered once weekly for 8 weeks) reduced serum TGs in C57Bl/6 mice with normal lipemia. After Evinacumab treatment, heparin LPL activity increased 1.8 times in C57Bl/6 mice and 2.5 times in db/db mice. Evinacumab (3 mg/kg or 10 mg/kg) reduced blood lipids in cynomolgus monkeys. [1] |
| Synonyms | REGN1500, REGN 1500 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | ANGPTL3 |
| Molecular Weight | 150 kDa |
| Cas No. | 1446419-85-7 |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Evinacumab chemical structure | Evinacumab in vivo | Evinacumab in vitro | Evinacumab molecular weight
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