T9222L |
Emlenoflast sodium
|
2380032-29-9
|
98%
|
|
Emlenoflast sodium, a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in...
|
T3701 |
MCC950
|
210826-40-7
|
98%
|
|
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
|
T9222 |
Emlenoflast
|
1995067-59-8
|
98%
|
|
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
|
T6591 |
Nodinitib-1
|
799264-47-4
|
99.98%
|
|
Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
|
T9572 |
BMS986299
|
2242952-69-6
|
99.93%
|
|
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
|
T4217 |
INF39
|
866028-26-4
|
99.67%
|
|
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
|
T61392 |
NLRP3-IN-10
|
2641826-39-1
|
99.63%
|
|
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...
|
TN1273 |
7,4'-Dihydroxyflavone
|
2196-14-7
|
99.6%
|
|
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
|
T3587 |
NOD-IN-1
|
132819-92-2
|
99.43%
|
|
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
|
T38361 |
GSK717
|
1595278-21-9
|
99.01%
|
|
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
|
T3230 |
NLRP3-IN-2
|
16673-34-0
|
98.98%
|
|
It is a NLRP3 Inflammasome Inhibitor I.
|
T25548 |
JC124
|
1638611-48-9
|
98.54%
|
|
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
|
T3092 |
Nigericin sodium salt
|
28643-80-3
|
98.2%
|
|
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
|
T6887 |
MCC950 sodium
|
256373-96-3
|
98.16%
|
|
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
|
T5838 |
L-Canavanine sulfate
|
2219-31-0
|
98%
|
|
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
|
T6S1367 |
Procyanidin B2
|
29106-49-8
|
97.69%
|
|
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
|
TN7099 |
Antcin A
|
163597-24-8
|
96.43%
|
|
antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
|
T7597 |
6-Biopterin
|
22150-76-1
|
95.95%
|
|
6-Biopterin is a natural product,is a NO synthase cofactor.
|
T15052 |
Dapansutrile
|
54863-37-5
|
|
|
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
|
T13375 |
YQ128
|
2454246-18-3
|
|
|
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
|