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NOD

Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules.
Cat. No. Product name CAS No. Purity Chemical Structure
T9222L Emlenoflast sodium 2380032-29-9 98%
Emlenoflast sodium, a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in...
T3701 MCC950 210826-40-7 98%
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
T9222 Emlenoflast 1995067-59-8 98%
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
T6591 Nodinitib-1 799264-47-4 99.98%
Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
T9572 BMS986299 2242952-69-6 99.93%
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
T4217 INF39 866028-26-4 99.67%
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
T61392 NLRP3-IN-10 2641826-39-1 99.63%
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...
TN1273 7,4'-Dihydroxyflavone 2196-14-7 99.6%
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
T3587 NOD-IN-1 132819-92-2 99.43%
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
T38361 GSK717 1595278-21-9 99.01%
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
T3230 NLRP3-IN-2 16673-34-0 98.98%
It is a NLRP3 Inflammasome Inhibitor I.
T25548 JC124 1638611-48-9 98.54%
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
T3092 Nigericin sodium salt 28643-80-3 98.2%
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
T6887 MCC950 sodium 256373-96-3 98.16%
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
T5838 L-Canavanine sulfate 2219-31-0 98%
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
T6S1367 Procyanidin B2 29106-49-8 97.69%
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
TN7099 Antcin A 163597-24-8 96.43%
antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
T7597 6-Biopterin 22150-76-1 95.95%
6-Biopterin is a natural product,is a NO synthase cofactor.
T15052 Dapansutrile 54863-37-5
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
T13375 YQ128 2454246-18-3
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
Emlenoflast sodium
T9222L
Emlenoflast sodium, a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in...
MCC950
T3701
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
Emlenoflast
T9222
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
Nodinitib-1
T6591
Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
BMS986299
T9572
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
INF39
T4217
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
NLRP3-IN-10
T61392
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...
7,4'-Dihydroxyflavone
TN1273
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
NOD-IN-1
T3587
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
GSK717
T38361
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
NLRP3-IN-2
T3230
It is a NLRP3 Inflammasome Inhibitor I.
JC124
T25548
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
Nigericin sodium salt
T3092
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
MCC950 sodium
T6887
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
L-Canavanine sulfate
T5838
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
Procyanidin B2
T6S1367
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
antcin A
TN7099
antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
6-Biopterin
T7597
6-Biopterin is a natural product,is a NO synthase cofactor.
Dapansutrile
T15052
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
YQ128
T13375
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
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