T60404 |
NLRP3/AIM2-IN-2
|
791840-86-3
|
98%
|
|
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0...
|
T60442 |
NLRP3/AIM2-IN-3
|
1787787-60-3
|
98%
|
|
NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0....
|
T9222L |
Emlenoflast sodium
|
2380032-29-9
|
98%
|
|
Emlenoflast sodium, a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in...
|
T28178 |
NLRP3-IN-9
|
88039-46-7
|
98%
|
|
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...
|
T15052 |
Dapansutrile
|
54863-37-5
|
98%
|
|
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
|
T4164 |
CY-09
|
1073612-91-5
|
98%
|
|
CY-09 is an NLRP3 inhibitor.
|
T7597 |
6-Biopterin
|
22150-76-1
|
98%
|
|
6-Biopterin is a natural product,is a NO synthase cofactor.
|
TN7099 |
Antcin A
|
163597-24-8
|
98%
|
|
antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
|
T7682 |
Asymmetric dimethylarginine
|
30315-93-6
|
98%
|
|
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
|
T5838 |
L-Canavanine sulfate
|
2219-31-0
|
98%
|
|
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
|
T2845 |
Imperatorin
|
482-44-0
|
98%
|
|
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
|
T25548 |
JC124
|
1638611-48-9
|
98%
|
|
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
|
T3230 |
NLRP3-IN-2
|
16673-34-0
|
98%
|
|
It is a NLRP3 Inflammasome Inhibitor I.
|
T38361 |
GSK717
|
1595278-21-9
|
98%
|
|
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
|
T6887 |
MCC950 sodium
|
256373-96-3
|
98%
|
|
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
|
T6S1367 |
Procyanidin B2
|
29106-49-8
|
98%
|
|
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
|
T0122 |
Bergenin
|
477-90-7
|
98%
|
|
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
|
T3092 |
Nigericin sodium salt
|
28643-80-3
|
98%
|
|
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
|
TN1273 |
7,4'-Dihydroxyflavone
|
2196-14-7
|
98%
|
|
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
|
TQ0165 |
Arglabin
|
84692-91-1
|
98%
|
|
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
|