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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library

NOD

Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules.
Cat. No. Product name CAS No. Purity Chemical Structure
T60404 NLRP3/AIM2-IN-2 791840-86-3 98%
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0...
T60442 NLRP3/AIM2-IN-3 1787787-60-3 98%
NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0....
T9222L Emlenoflast sodium 2380032-29-9 98%
Emlenoflast sodium, a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in...
T28178 NLRP3-IN-9 88039-46-7 98%
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...
T15052 Dapansutrile 54863-37-5 98%
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
T4164 CY-09 1073612-91-5 98%
CY-09 is an NLRP3 inhibitor.
T7597 6-Biopterin 22150-76-1 98%
6-Biopterin is a natural product,is a NO synthase cofactor.
TN7099 Antcin A 163597-24-8 98%
antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
T7682 Asymmetric dimethylarginine 30315-93-6 98%
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
T5838 L-Canavanine sulfate 2219-31-0 98%
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
T2845 Imperatorin 482-44-0 98%
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T25548 JC124 1638611-48-9 98%
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
T3230 NLRP3-IN-2 16673-34-0 98%
It is a NLRP3 Inflammasome Inhibitor I.
T38361 GSK717 1595278-21-9 98%
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
T6887 MCC950 sodium 256373-96-3 98%
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
T6S1367 Procyanidin B2 29106-49-8 98%
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
T0122 Bergenin 477-90-7 98%
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
T3092 Nigericin sodium salt 28643-80-3 98%
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
TN1273 7,4'-Dihydroxyflavone 2196-14-7 98%
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
TQ0165 Arglabin 84692-91-1 98%
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
NLRP3/AIM2-IN-2
T60404
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0...
NLRP3/AIM2-IN-3
T60442
NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0....
Emlenoflast sodium
T9222L
Emlenoflast sodium, a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in...
NLRP3-IN-9
T28178
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...
Dapansutrile
T15052
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
CY-09
T4164
CY-09 is an NLRP3 inhibitor.
6-Biopterin
T7597
6-Biopterin is a natural product,is a NO synthase cofactor.
antcin A
TN7099
antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
Asymmetric dimethylarginine
T7682
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
L-Canavanine sulfate
T5838
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
Imperatorin
T2845
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
JC124
T25548
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
NLRP3-IN-2
T3230
It is a NLRP3 Inflammasome Inhibitor I.
GSK717
T38361
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
MCC950 sodium
T6887
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
Procyanidin B2
T6S1367
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
Bergenin
T0122
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
Nigericin sodium salt
T3092
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
7,4'-Dihydroxyflavone
TN1273
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
Arglabin
TQ0165
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
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