NOD

Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules.

Cat. No.	Product name	CAS No.	Purity
T9222L	Emlenoflast sodium	2380032-29-9	98%
Emlenoflast sodium, a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in...
T3701	MCC950	210826-40-7	98%
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
T9222	Emlenoflast	1995067-59-8	98%
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
T6591	Nodinitib-1	799264-47-4	99.98%
Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
T9572	BMS986299	2242952-69-6	99.93%
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
T4217	INF39	866028-26-4	99.67%
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
T61392	NLRP3-IN-10	2641826-39-1	99.63%
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...
TN1273	7,4'-Dihydroxyflavone	2196-14-7	99.6%
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
T3587	NOD-IN-1	132819-92-2	99.43%
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
T38361	GSK717	1595278-21-9	99.01%
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
T3230	NLRP3-IN-2	16673-34-0	98.98%
It is a NLRP3 Inflammasome Inhibitor I.
T25548	JC124	1638611-48-9	98.54%
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
T3092	Nigericin sodium salt	28643-80-3	98.2%
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
T6887	MCC950 sodium	256373-96-3	98.16%
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
T5838	L-Canavanine sulfate	2219-31-0	98%
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
T6S1367	Procyanidin B2	29106-49-8	97.69%
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
TN7099	Antcin A	163597-24-8	96.43%
antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
T7597	6-Biopterin	22150-76-1	95.95%
6-Biopterin is a natural product,is a NO synthase cofactor.
T15052	Dapansutrile	54863-37-5
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
T13375	YQ128	2454246-18-3
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T9222L

Emlenoflast sodium

2380032-29-9

98%

Emlenoflast sodium, a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in...

T3701

MCC950

210826-40-7

98%

CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...

T9222

Emlenoflast

1995067-59-8

98%

Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.

T6591

Nodinitib-1

799264-47-4

99.98%

Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.

T9572

BMS986299

2242952-69-6

99.93%

BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.

T4217

INF39

866028-26-4

99.67%

INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.

T61392

NLRP3-IN-10

2641826-39-1

99.63%

NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading t...

TN1273

7,4'-Dihydroxyflavone

2196-14-7

99.6%

4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.

T3587

NOD-IN-1

132819-92-2

99.43%

NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.

T38361

GSK717

1595278-21-9

99.01%

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...

T3230

NLRP3-IN-2

16673-34-0

98.98%

It is a NLRP3 Inflammasome Inhibitor I.

T25548

JC124

1638611-48-9

98.54%

JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.

T3092

Nigericin sodium salt

28643-80-3

98.2%

Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...

T6887

MCC950 sodium

256373-96-3

98.16%

MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.

T5838

L-Canavanine sulfate

2219-31-0

98%

L-Canavanine sulfate is a selective inducible NO synthase inhibitor.

T6S1367

Procyanidin B2

29106-49-8

97.69%

Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...

TN7099

Antcin A

163597-24-8

96.43%

antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...

T7597

6-Biopterin

22150-76-1

95.95%

6-Biopterin is a natural product,is a NO synthase cofactor.

T15052

Dapansutrile

54863-37-5

Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.

T13375

YQ128

2454246-18-3

YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.