undergoing — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14364	AZ-Dyrk1B-33	3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine	DYRK
	AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.		DYRK
T39312	2-Hexylthiophene		Others
	2-Hexylthiophene, a weakly basic heteroaromatic compound, can enhance the molar absorption coefficient of ruthenium sensitizers by undergoing modification.		Others
T0230	Prasugrel	LY640315,CS-747,PCR 4099	P2Y Receptor
	Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those...		P2Y Receptor
TP1236	Etelcalcetide hydrochloride	AMG 416 hydrochloride,KAI-4169 hydrochloride	CaSR
	Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that acts as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively lowering parathyroid hormone (PTH) levels in patients wi...		CaSR
T3614	Inosine pranobex	Groprinosin,Isoprinosine,Immunovir,Delimmun	IL Receptor , HIV Protease
	Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects a...		IL Receptor , HIV Protease
T21537L	TMC647055 Choline Hydroxide Salt	TMC647055 Choline Hydroxide Salt (1204416-97-6 free base)	HCV Protease
	TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. It has nanomolar cellular potency (EC(50) of 82 nM) with mi...		HCV Protease
T68312	Etanterol
	Etanterol is a phenethanolamine derivative and a β2 adrenoceptor agonist that was undergoing phase II trials in Italy as a bronchodilator with Valeas.
T69961	CJ-15161 (free base)
	CJ-15161 (free base), an opioid κ-receptor agonist, is undergoing development with Pfizer as an analgesic agent.
T71154	SX-576
	SX-576 is undergoing further investigation as a potential therapy for pulmonary inflammation. It is also a potent non-competitive boronic acid-containing CXCR1/2 antagonists.
T69960	CJ-15161 hydrochloride
	CJ-15161 hydrochloride is the salt form of CJ-15161 (free base), an opioid κ-receptor agonist, is undergoing development with Pfizer as an analgesic agent.
T6287L	Tariquidar dimesylate	D 06008,XR9576,D06008,XR 9576,Tariquidar dimesilate,XR-9576
	Tariquidar is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane t...
TP1235	Etelcalcetide	AMG 416,KAI-4169
	Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodi...
T12610	(R)-3-Hydroxy Midostaurin	(R)-CGP52421	Others
	(R)-3-Hydroxy Midostaurin is a potent inhibitor of kinases,is a major metabolite of midostaurin undergoing by the hepatic CYP3A4 enzyme,has the potential for acute myeloid leukemia (AML).		Others
T37437	C17 Ceramide (d18:1/17:0)
	C17 Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine. It has been used as a marker of arylsulfatase A and sphingolipid activator B activity in patients undergoing enzy...
T68639	Ciprostene (free base)
	Ciprostene (free base) is a synthetic, chemically stable analog of prostacyclin (PGI2). In animal models, administration of ciprostene resulted in dose-dependent hypotension, tachycardia, and inhibition of ex vivo ADP-in...
T69557	ABI-231 HCl
	ABI-231 is a potent, orally bioavailable tubulin inhibitor that interacts with the colchicine binding site and is currently undergoing clinical trials for prostate cancer. ABI-231, has an average IC50 = 5.2 nM against pa...
T82799	C-2′-Decoumaroylaloeresin G
	Compound 1059182-21-6 features a cyclic structure characterized by a nitrogen atom occupying an apex (corner) within the heterocycle. Its molecular scaffold integrates aromatic properties due to the presence of a conjuga...
T82006	JM3A
	JM3A, a highly specific peptoid reagent, selectively targets cell surface vimentin (CSV) on early lung cancer cells undergoing tumor transformation. By conjugating with fluorophores [1], JM3A detects and stains CSV, enab...
T82654	Cy3-PEG3-TCO4
	Cy3-PEG3-TCO4, a dye derivative with three polyethylene glycol (PEG) units linked to Cyanine 3 (Cy3), possesses a trans-cyclooctene (TCO) group capable of undergoing the inverse electron demand Diels-Alder reaction (iEDD...
T71549	RKS-262
	RKS262 is a specific cyclin/CDK inhibitor. RKS262 was identified by structural optimization of Nifurtimox which is currently undergoing phase II clinical trials to treat high-risk neuroblastoma. In a NCI(60) cell-line as...