tool compound

EPZ020411 is a specific and effective inhibitor of PRMT6 (IC50=10 nM).

Atinvicitinib, a selective Janus kinase (JAK) inhibitor, demonstrates high specificity for Janus kinase 1 (JAK1), consequently inhibiting downstream cytokine signaling pathways that rely on JAK1 enzymatic activity. Atinvicitinib modulates a wide range of cytokines that are implicated in itch responses, allergic reactions, and inflammatory conditions, making it a significant research tool for studying cytokine-mediated immune processes as well as therapeutic modulation of allergic and inflammatory diseases.

3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used in the study of neurological disorders and cancer.

BRK inhibitor P21d hydrochloride is a highly potent inhibitor of breast tumor kinase (BRK PTK6), displaying an IC50 of 30 nM, and effectively suppresses p-SAM68 with an IC50 of 52 nM. This compound serves as a valuable tool for evaluating BRK inhibitors' efficacy in xenograft breast tumor models, enabling in vivo activity assessment.

CC214-1 is an mTOR inhibitor with potential anticancer activity, inhibits protein translation, and induces autophagy. CC214-1 is an in vitro tool compound for exploring the biology of mTOR kinases and can be used to study myeloma.

JAK3-IN-11 (Compound 12) exhibits potent, noncytotoxic, irreversible, orally active JAK3 inhibitory activity (IC50 = 1.7 nM) with an excellent selectivity profile (>588-fold compared to other JAK isoforms), covalently binds to the ATP-binding pocket in JAK3. JAK3-IN-11 strongly inhibits JAK3-dependent signaling and T-cell proliferation which is a promising tool for studying autoimmune diseases [1].

Compound FL0001, with CAS No. 479553-01-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0001 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0002, with CAS No. 189089-90-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0002 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0003, with CAS No. 1067193-34-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0003 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0004, with CAS No. 800402-07-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0004 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0036, with CAS No. 142733-64-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0036 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0044, with CAS No. 345965-52-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0044 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0066, with CAS No. 927679-54-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0066 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0101, with CAS No. 396074-50-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0101 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0105, with CAS No. 117642-16-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0105 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0107, with CAS No. 171049-41-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0107 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0108, with CAS No. 20348-21-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0108 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0113, with CAS No. 1017783-09-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0113 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0122, with CAS No. 193537-14-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0122 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0148, with CAS No. 1694-06-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0148 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0151, with CAS No. 1788054-84-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0151 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0152, with CAS No. 120737-78-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0152 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0153, with CAS No. 278788-66-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0153 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0165, with CAS No. 398491-59-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0165 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.