psc

Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.

Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.

Valspodar (PSC 833) is a small-molecule inhibitor and a P-glycoprotein (P-gp) inhibitor with high selectivity and chemosensitizing properties. This compound can effectively reverse P-gp-mediated multidrug resistance (MDR) and is used in experimental research on drug-resistant tumors such as advanced epithelial ovarian cancer.

PrPSc-IN-1 is a fluorescent probe that binds to the misfolded protein PrPSc, inhibits its accumulation with an IC50 of 1.6 μM, and exhibits anti-prion activity.

PSCdb01560 is an inhibitor of the Dengue virus NS5 RNA-dependent RNA polymerase (RdRp). It binds stably to the polymerase's conserved allosteric N pocket, maintaining persistent interactions with key residues Arg729 and Arg737, inducing structural stability in the polymerase. PSCdb01560 is applicable in research related to Dengue virus infection.

OpSCF is an antibody targeting SCF and can be used for immunology research.

Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.

DADPS Biotin Azide (Biotin-PEG4-amino-t-Bu-DADPS-C6-azide) is a PROTAC linker and a chemical linking unit used for constructing proteolysis-targeting chimeras, featuring favorable chemical cleavability and bioorthogonal reactivity, commonly employed in the synthesis of PROTAC molecules with targeted protein degradation functionality.

Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter that mainly acts on dopamine receptors (D1-5 receptors) (EC50=2.7 nM). Dopamine hydrochloride induces VEGFR2 endocytosis through D2 dopamine receptor and has pro-angiogenic activity.

Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.

Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).

Biotin-PEG4-amino-t-Bu-DADPS-C3-alkyne serves as a PEG-based linker for PROTAC synthesis [1].

(S)-P-SCN-BN-NOTA TFA can be conjugated with PDGFRβ affinity ligands for subsequent radiolabeling. It is also applicable in pancreatic cancer research.

p-SCN-Bn-TCMC is a bifunctional chelator, it contains a powerful chelator TCMC and reactive tioisocyante linker. TCMC is a powerful chelator with capability to strongly bind radio-isotopic heavy metal ion, which are widely used for radio-diagnostic/imagin

p-SCN-Bn-HOPO is an excellent bifunctional chelating agent for (89)Zr ImmunoPET, with low background, good tumor-organ contrast, and importantly, very low bone uptake for BT474 breast cancer imaging.

p-SCN-Bn-DOTA is a chelator that simultaneously binds radionuclides and links monoclonal antibodies. It is utilized as a tracer for radio-guided surgery and serves in radio-immunoassay studies of tumors.

L-α-lysophosphatidylinositol sodium is an endogenous ligand of GPR55 and an endogenous cannabinoid neurotransmitter that is involved in controlling cell survival and tumor progression.

SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].

SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].

BCH001 is a specific small-molecule inhibitor of PAPD5.

SBC-115337 is a PCSK9 inhibitor.

2-NP-SCA-13C,15N2 (Standard) is a reference standard of 2-NP-SCA-13C,15N2 intended for quantitative analysis, quality control, and related biochemical research applications.

mNLS-CPP-scramble serves as a negative control peptide for mNLS-CPP-WSTF. It shows potential for research into chronic inflammatory diseases, such as MASH and osteoarthritis.

mNLS-CPP-scramble (TFA) is the trifluoroacetate salt form of mNLS-CPP-scramble. Serving as a negative control peptide for mNLS-CPP-WSTF, it holds potential for research in chronic inflammatory diseases, such as MASH and osteoarthritis.