nap a

Acecainide hydrochloride (NAPA) is the major hepatic metabolite of procainamide and its antiarrhythmic effects may lead to cardiotoxicity in renal failure.

N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic drug.

NAP-1 is a compound with anesthetic activity.1 It increases paired-pulse inhibition in the CA1 region of rat hippocampal brain slices when used at a concentration of 100 μM. NAP-1 also induces loss of righting reflex in tadpoles (EC50 = 0.53 μM).References NAP-1 is a compound with anesthetic activity.1 It increases paired-pulse inhibition in the CA1 region of rat hippocampal brain slices when used at a concentration of 100 μM. NAP-1 also induces loss of righting reflex in tadpoles (EC50 = 0.53 μM). References

Compound 16, also known as 25N-N1-Nap, functions as a β-arrestin-biased 5-HT2A agonist. It effectively antagonizes phencyclidine-induced hyperactivity in male C57BL/6J mice [1].

Nap-FF is a cell-penetrating dipeptide used in the preparation of hydrogel chemical sensors and for research in targeted drug delivery.

5'-O-DMTr-Nap-dU-3'-CE Phosphoramidite is a phosphoramidite monomer that can be utilized in nucleic acid synthesis, including oligonucleotides.

(Gly0.8Nap0.2)20 is a dual-target compound effective against fungal membranes and DNA. It exhibits antimicrobial properties.

NAP1051, a biomimetic analog of Lipoxin A4, serves an anti-tumor role by targeting the inflammatory tumor microenvironment. It inhibits the chemotaxis of neutrophils to fMLP and stimulates macrophage efferocytosis by activating AKT. NAP1051 is utilized in research on colorectal cancer.

Lonapalene (RS4317) is a 5-lipoxygenase (5-LO) inhibitor with anti-psoriasis efficacy.Lonapalene topically blocks skin inflammation.

Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.

Fanapanel hydrate is a highly selective antagonist of AMPA/kainate with little activity against NMDA(Ki of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively).

Fanapanel (ZK200775) is a quinoxalinedione derivative and potent competitive antagonist of AMPAR for cerebrovascular-related studies.

ASTX660 is an innovative non-peptide mimic antagonist targeting cIAP1/2 and XIAP, effectively inducing TNFα-dependent apoptosis in cancer cell lines and inhibiting tumor growth.

Phencarbamide napadisilate is an antispasmodic and anticholinergic compound used during labor.

Methyl clofenapate (Clofenapate methyl ester; MCP) is a peroxisome proliferator that can induce hypolipidemia, peroxisome proliferation, and hepatocarcinogenesis.

NAPAP is a thrombin inhibitor with potent anticoagulant activity (Ki: 2.1 nM). It selectively inhibits thrombin through a rapid binding mechanism while exhibiting weaker inhibition of trypsin, Factor Xa, and plasmin. NAPAP can be utilized for research into thrombotic conditions, including venous thrombosis and myocardial infarction.

Repunapanor (compound 123) is a potent inhibitor of the sodium/hydrogen exchanger isoform 3 [Na+/H+ exchanger 3 (NHE-3)].

Abediterol napadisylate is a novel long-acting β2-agonist in persistent asthma that is efficacy, safe, and tolerable.

Aclatonium Napadisilate, a cholinergic agonist, has been shown to stimulates endocrine and exocrine pancreatic secretion.

Napamezole is an α2 adrenergic receptor antagonist. Napamezole antagonizes methoxamine-induced contractions (alpha-1) of the rat vas deferens with a Kb of 135 nM. Napamezole reverses clonidine-induced decreased in twitch height in the electrically stimula

Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.

L-Napamp is a bioactive chemical.

Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.