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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T72285 | LC kinetic stabilizer-1 | ||
LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WI... | |||
T72286 | LC kinetic stabilizer-2 | ||
LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM. | |||
T0699 | Sulfamonomethoxine | Antibacterial , Antibiotic | |
Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent, blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate. | |||
T18888 | 4-Methylumbelliferyl phosphate | 4-MUP | Others |
4-Methylumbelliferyl phosphate (4-MUP) (4-MUP) is used as a fluorogenic substrate of alkaline phosphatases. | |||
T76304 | Adipokinetic hormone II (Locusta migratoria) | ||
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II), an insect adipokinetic hormone (AKH), elevates fat body cAMP levels in vitro. These hormones (AKHs) regulate the mobilization of carbohydrates and lipids from fa... | |||
T76655 | Prokineticin 2 Isoform 2 (human) | ||
Prokineticin 2 Isoform 2 (human), a hypothalamic neuropeptide, regulates thermoregulation and energy metabolism while decreasing food intake in rodents. This isoform is implicated in the study of metabolic syndrome (MetS... | |||
T83167 | Adipokinetic Hormone (AKH) (24-32), locust TFA | ||
Adipokinetic Hormone (AKH) (24-32), locust (TFA), a neurohormone extracted from the corpora cardiaca of locusts, serves to regulate lipid utilization during flight [1]. | |||
T76306 | Adipokinetic hormone I (Locusta migratoria) | ||
Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I), an insect adipokinetic hormone (AKH), increases fat body cAMP levels in vitro. AKHs regulate the mobilization of carbohydrates and lipids from fat body stores for ... | |||
T83166 | Adipokinetic hormone (Gryllus bimaculatus) | Grybi-AKH | |
Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH), an adipokinetic hormone, mobilizes lipids and carbohydrates from the insect fat body, effectively regulating energy homeostasis. It also enhances the locomotor activi... | |||
TP1757 | Adipokinetic Hormone (AKH) (24-32), locust | ||
Adipokinetic Hormone (AKH) (24-32), locust is a peptide hormone isolated from locusts. | |||
T83165 | Adipokinetic hormone (Manduca sexta) | Manse-AKH | |
Adipokinetic Hormone (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta), a peptide shared by diverse insects, elicits a potent adipokinetic/hypertrehalosemic response. Despite this, it lacks the functi... | |||
T39740 | Acoramidis hydrochloride | AG10 hydrochloride,Alxn2060 hydrochloride | Others |
Acoramidis hydrochloride (Alxn2060 hydrochloride) is an orally active and selective kinetic stabilizer of WT and V122I- TTR (transthyretin) . Acoramidis hydrochloride is used in the study for transthyretin amyloidosis. | |||
T7582 | Tafamidis meglumine | Fx-1006A | Others |
Tafamidis meglumine (Fx-1006A) is a Potent and Selective Transthyretin Kinetic Stabilizer That Inhibits the Amyloid Cascade | |||
T9447 | AG-10 | Acoramidis | Others |
AG-10 (Acoramidis) is an orally active and selective kinetic stabilizer of TTR (transthyretin). AG-10 exhibits activity for WT and V122I-TTR. AG-10 is used in the study of transthyretin amyloidosis. | |||
T9361 | 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione | 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | Others |
5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione (5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthetic compound. It has been used as a catalyst and as a tool in enzyme kinetic studies; it has al... | |||
T4565 | Tafamidis | Fx-1006A | Others |
Tafamidis (Fx-1006A) is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1: 3 nM; Kd2: 278 nM) to stabilize the TTR di... | |||
T4S0145 | Corylifol A | Corylinin | hCE , STAT , UGT |
1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia... | |||
T21537L | TMC647055 Choline Hydroxide Salt | TMC647055 Choline Hydroxide Salt (1204416-97-6 free base) | HCV Protease |
TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. It has nanomolar cellular potency (EC(50) of 82 nM) with mi... | |||
T6707 | Tiotropium Bromide hydrate | BA-679 BR hydrate,BA 679BR | AChR |
Tiotropium Bromide hydrate (BA-679 BR hydrate) is a potent anticholinergic and bronchodilator, serving as a muscarinic receptor antagonist, specifically targeting mAChR. It is developed for treating chronic obstructive a... | |||
T24001 | Diisopropyl tartrate | Diisopropyl (+)-L-tartrate,L-DIPT,BRN 1727863 | |
Diisopropyl tartrate is a reagent for kinetic resolution of racemic allylic alcohols and α-furfuryl amides. It acts by enantioselective epoxidation. |