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Search Results for " kinetic "

20

Compounds

Cat No. Product Name Synonyms Targets
T72285 LC kinetic stabilizer-1
LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WI...
T72286 LC kinetic stabilizer-2
LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.
T0699 Sulfamonomethoxine Antibacterial , Antibiotic
Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent, blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
T18888 4-Methylumbelliferyl phosphate 4-MUP Others
4-Methylumbelliferyl phosphate (4-MUP) (4-MUP) is used as a fluorogenic substrate of alkaline phosphatases.
T76304 Adipokinetic hormone II (Locusta migratoria)
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II), an insect adipokinetic hormone (AKH), elevates fat body cAMP levels in vitro. These hormones (AKHs) regulate the mobilization of carbohydrates and lipids from fa...
T76655 Prokineticin 2 Isoform 2 (human)
Prokineticin 2 Isoform 2 (human), a hypothalamic neuropeptide, regulates thermoregulation and energy metabolism while decreasing food intake in rodents. This isoform is implicated in the study of metabolic syndrome (MetS...
T83167 Adipokinetic Hormone (AKH) (24-32), locust TFA
Adipokinetic Hormone (AKH) (24-32), locust (TFA), a neurohormone extracted from the corpora cardiaca of locusts, serves to regulate lipid utilization during flight [1].
T76306 Adipokinetic hormone I (Locusta migratoria)
Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I), an insect adipokinetic hormone (AKH), increases fat body cAMP levels in vitro. AKHs regulate the mobilization of carbohydrates and lipids from fat body stores for ...
T83166 Adipokinetic hormone (Gryllus bimaculatus) Grybi-AKH
Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH), an adipokinetic hormone, mobilizes lipids and carbohydrates from the insect fat body, effectively regulating energy homeostasis. It also enhances the locomotor activi...
TP1757 Adipokinetic Hormone (AKH) (24-32), locust
Adipokinetic Hormone (AKH) (24-32), locust is a peptide hormone isolated from locusts.
T83165 Adipokinetic hormone (Manduca sexta) Manse-AKH
Adipokinetic Hormone (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta), a peptide shared by diverse insects, elicits a potent adipokinetic/hypertrehalosemic response. Despite this, it lacks the functi...
T39740 Acoramidis hydrochloride AG10 hydrochloride,Alxn2060 hydrochloride Others
Acoramidis hydrochloride (Alxn2060 hydrochloride) is an orally active and selective kinetic stabilizer of WT and V122I- TTR (transthyretin) . Acoramidis hydrochloride is used in the study for transthyretin amyloidosis.
T7582 Tafamidis meglumine Fx-1006A Others
Tafamidis meglumine (Fx-1006A) is a Potent and Selective Transthyretin Kinetic Stabilizer That Inhibits the Amyloid Cascade
T9447 AG-10 Acoramidis Others
AG-10 (Acoramidis) is an orally active and selective kinetic stabilizer of TTR (transthyretin). AG-10 exhibits activity for WT and V122I-TTR. AG-10 is used in the study of transthyretin amyloidosis.
T9361 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Others
5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione (5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthetic compound. It has been used as a catalyst and as a tool in enzyme kinetic studies; it has al...
T4565 Tafamidis Fx-1006A Others
Tafamidis (Fx-1006A) is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1: 3 nM; Kd2: 278 nM) to stabilize the TTR di...
T4S0145 Corylifol A Corylinin hCE , STAT , UGT
1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...
T21537L TMC647055 Choline Hydroxide Salt TMC647055 Choline Hydroxide Salt (1204416-97-6 free base) HCV Protease
TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. It has nanomolar cellular potency (EC(50) of 82 nM) with mi...
T6707 Tiotropium Bromide hydrate BA-679 BR hydrate,BA 679BR AChR
Tiotropium Bromide hydrate (BA-679 BR hydrate) is a potent anticholinergic and bronchodilator, serving as a muscarinic receptor antagonist, specifically targeting mAChR. It is developed for treating chronic obstructive a...
T24001 Diisopropyl tartrate Diisopropyl (+)-L-tartrate,L-DIPT,BRN 1727863
Diisopropyl tartrate is a reagent for kinetic resolution of racemic allylic alcohols and α-furfuryl amides. It acts by enantioselective epoxidation.
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