Search Result

Search Results for " guanine "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T3186	NU2058	O6-(Cyclohexylmethyl)guanine,O(6)-Cyclohexylmethylguanine	Topoisomerase , CDK
	NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.		Topoisomerase , CDK
T29689	AFB1-N7-guanine
	In epidemiological studies, Aflatoxin B1-N7-guanine serum albumin adducts have been established as biomarkers of dietary aflatoxin exposure.
TNU1326	N-Trityl-morpholino guanine
	N-Trityl-morpholino guanine is a nucleoside derivative-morpholino nucleoside.
TNU0267	9-(b-D-Xylofuranosyl)guanine
	9-(b-D-Xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside.
TNU1437	(S)-9-(2,3-Dihydroxypropyl)-guanine
	(S)-9-(2,3-Dihydroxypropyl)-guanine is a nucleoside derivative-acyclic nucleoside.
TNU0794	N2-acetyl-O6-(diphenylcarbamoyl)guanine
	N2-acetyl-O6-(diphenylcarbamoyl)guanine is a useful organic compound for research related to life sciences. The catalog number is TNU0794 and the CAS number is 112 233-74-6.
TNU0891	N2-Boc-guanine-9-acetic acid
	N2-Boc-guanine-9-acetic acid is a PNA-related derivative, a PNA monomer.
TNU0384	8-Benzyloxy-9-(b-D-xylofuranosyl)guanine
	8-Benzyloxy-9-(b-D-xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside; 8-modified purine nucleoside.
TNU1438	N2-Isobutyryl-(S)-9-(2,3-dihydroxypropyl)-guanine
	N2-Isobutyryl-(S)-9-(2,3-dihydroxypropyl)-guanine is a nucleoside derivative-acyclic nucleoside.
TNU1327	7’-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine
	7’-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine is a nucleoside derivative-morpholino nucleoside.
TNU0382	8-Bromo-9-(b-D-xylofuranosyl)guanine
	8-Bromo-9-(b-D-xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside; 8-modified purine nucleoside.
TNU1589	N2-Isobutyryl-7’-OH-N-DMTr-morpholino guanine
	N2-Isobutyryl-7’-OH-N-DMTr-morpholino guanine is a nucleoside derivative-morpholino nucleoside.
TNU1328	N2-Phenylacetyl-7’-OH-N-trityl-morpholino guanine
	Nucleoside Derivatives - Morpholino nucleosides; Protected nucleosides w/ NH2/OH open
TNU0385	1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine
	1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside; 8-modified purine nucleoside; amino nucleoside.
TNU1221	N2-Isobutyryl-O6-cyanoethyl-7’-OH-N-trityl-morpholino guanine
	Nucleoside Derivatives - Morpholino nucleosides; Protected nucleosides w/ NH2/OH open
TNU0394	7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-ribofuranosyl)guanine
	7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-ribofuranosyl)guanine is a useful organic compound for research related to life sciences and the catalog number is TNU0394.
TNU0386	1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine
	1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine is a nucleoside derivative-xylo-nucleoside; 8-modified purine nucleoside; amino nucleoside.
TNU0388	7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine
	Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; N-Methylated alkylated nucleosides
TNU0383	7-Allyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine
	Nucleoside Derivatives - Xylo nucleosides, 8-Modified purine nucleosides; N-Methylated alkylated nucleosides
TNU0437	7-Ethyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine
	7-Ethyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside, N-methylated alkylated nucleoside.
TNU0440	7-Propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine
	7-Propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside, N-methylated alkylated nucleoside.
TNU0438	7-n-Propyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine
	7-n-Propyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside, N-methylated alkylated nucleoside.
TNU0439	7-n-Butyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine
	7-n-Butyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside, N-methylated alkylated nucleoside.
T75052	7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine
	7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms...
TNU0387	1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine
	Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosides
TNU0441	7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine
	7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a nucleoside derivative-xylo-nucleoside, N-methylated alkylated nucleoside.
T7539	O6-Benzylguanine		Apoptosis , DNA Alkylation , DNA/RNA Synthesis
	O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.		Apoptosis , DNA Alkylation , DNA/RNA Synthesis
TNU1604	2’-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3’-O-(4,4’-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine
	2'-O-(2-Cyanoethoxy)(diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-R-9-(2,3-dihydroxypropyl)-guanine is a nucleoside derivative
T1646	Famciclovir	BRL 42810	DNA/RNA Synthesis , HSV
	Famciclovir (BRL 42810) is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor.		DNA/RNA Synthesis , HSV
TNU1309	TLR7 agonist 10
	TLR7 agonist 10 is a nucleoside derivative-xylo-nucleoside, N-methylated alkylated nucleoside; 8-modified purine nucleoside.
T36411	9-Ethylguanine		Others
	9-Ethylguanine is a model nucleobase that is used to study DNA interactions with organometallic complexes, especially those designed to target tumors.		Others
T3089	6-Thioguanine	6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine	Apoptosis , DNA Methyltransferase , SARS-CoV , Endogenous Metabolite , DUB , Autophagy
	6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
T36697	8-Nitroguanine
	8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma.
TNU1450	N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine
	Nucleoside Derivatives - Morpholino nucleosides
T40911	9-Carboxymethoxymethylguanine
	9-Carboxymethoxymethylguanine is the primary metabolite derived from Aciclovir, a guanosine analogue with potent antiviral properties. Aciclovir, also known as Acyclovir, acts as an orally active antiviral agent.
T78379	9-Deazaguanine		Others
	9-Deazaguanine is a nucleoside analog that exhibits potent inhibitory activity against purine nucleoside phosphorylase (PNP) [1].		Others
T19148	5-Aza-7-deazaguanine		Others
	5-Aza-7-deazaguanine is a substrate for E. coli purine nucleoside phosphorylase (wild-type/Ser90Ala mutant) in the synthesis of base-modified nucleosides.		Others
TNU1439	(S)-9-[3-(4,4’-Dime thoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine
	(S)-9-[3-(4,4’-Dime thoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine is a nucleoside derivative-acyclic nucleoside.
TNU0023	6-Chloroguanineriboside
	6-Chloroguanineriboside is a halo nucleoside.
T31406	Dezaguanine	Dezaguanina,NSC 261726,CI-908,CI 908
	Dezaguanine is a novel antipurine antimetabolite with significant activity against transplantable rodent solid tumors, particularly breast adenocarcinoma.
T20102	8-Azahypoxanthine	NSC 22709,NSC-22709,NSC22709	Nucleoside Antimetabolite/Analog
	8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.		Nucleoside Antimetabolite/Analog
T9517	Arprinocide		Others
	Arprinocid is an inhibitor of hypoxanthine-guanine transport		Others
T37636	2'-Deoxyguanosine 5'-monophosphate disodium
	2’-Deoxyguanosine 5’-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase. 2’-Deoxyguanosine 5’-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative[1...
T67813	Tivicilovir	AM188	HBV , Antifection
	Tivicilovir (AM188) is a hepatitis B virus inhibitor. tiviclovir is a guanine-related acyclic 2'-deoxyguanine analogue with anti-herpesvirus activity.		HBV , Antifection
T16886	Sinefungin	Adenosyl-Ornithine,A-9145,Antibiotic 32232RP	Others , Histone Methyltransferase , Antibiotic , Antifungal
	Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates r...
T0189	Pemetrexed	Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate	DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
	Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).		DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
T9985	Methyl methanesulfonate		DNA Alkylation
	Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.		DNA Alkylation
TP2131L	Rac1 Inhibitor W56 acetate(1095179-01-3 free base)		Rho
	Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1.		Rho
T2495	Lomeguatrib	PaTrin-2	DNA Methyltransferase , DNA Alkylation
	Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .		DNA Methyltransferase , DNA Alkylation
T8527	CPYPP		Others
	CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPY...		Others

Compounds

NU2058

T3186

Synonym: O6-(Cyclohexylmethyl)guanine,O(6)-Cyclohexylmethylguanine

Target: Topoisomerase, CDK

N-Trityl-morpholino guanine

TNU1326

Synonym:

Target:

9-(b-D-Xylofuranosyl)guanine

TNU0267

Synonym:

Target:

(S)-9-(2,3-Dihydroxypropyl)-guanine

TNU1437

Synonym:

Target:

N2-acetyl-O6-(diphenylcarbamoyl)guanine

TNU0794

Synonym:

Target:

N2-Boc-guanine-9-acetic acid

TNU0891

Synonym:

Target:

8-Benzyloxy-9-(b-D-xylofuranosyl)guanine

TNU0384

Synonym:

Target:

N2-Isobutyryl-(S)-9-(2,3-dihydroxypropyl)-guanine

TNU1438

Synonym:

Target:

7’-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine

TNU1327

Synonym:

Target:

8-Bromo-9-(b-D-xylofuranosyl)guanine

TNU0382

Synonym:

Target:

N2-Isobutyryl-7’-OH-N-DMTr-morpholino guanine

TNU1589

Synonym:

Target:

N2-Phenylacetyl-7’-OH-N-trityl-morpholino guanine

TNU1328

Synonym:

Target:

1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine

TNU0385

Synonym:

Target:

N2-Isobutyryl-O6-cyanoethyl-7’-OH-N-trityl-morpholino guanine

TNU1221

Synonym:

Target:

7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-ribofuranosyl)guanine

TNU0394

Synonym:

Target:

1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine

TNU0386

Synonym:

Target:

7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine

TNU0388

Synonym:

Target:

7-Allyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine

TNU0383

Synonym:

Target:

7-Ethyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine

TNU0437

Synonym:

Target:

7-Propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine

TNU0440

Synonym:

Target:

7-n-Propyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine

TNU0438

Synonym:

Target:

7-n-Butyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine

TNU0439

Synonym:

Target:

7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine

T75052

Synonym:

Target:

1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine

TNU0387

Synonym:

Target:

7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine

Target: Apoptosis, DNA Alkylation, DNA/RNA Synthesis

2’-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3’-O-(4,4’-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine

Target: DNA/RNA Synthesis, HSV

Synonym: 6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine

Target: Apoptosis, DNA Methyltransferase, SARS-CoV, Endogenous Metabolite, DUB, Autophagy

N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine

TNU1450

Synonym:

Target:

9-Carboxymethoxymethylguanine

(S)-9-[3-(4,4’-Dime thoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine

TNU1439

Synonym:

Target:

6-Chloroguanineriboside

Synonym: Dezaguanina,NSC 261726,CI-908,CI 908

Target:

8-Azahypoxanthine

T20102

Synonym: NSC 22709,NSC-22709,NSC22709

Target: Nucleoside Antimetabolite/Analog

2'-Deoxyguanosine 5'-monophosphate disodium

Target: HBV, Antifection

Sinefungin

T16886

Synonym: Adenosyl-Ornithine,A-9145,Antibiotic 32232RP

Target: Others, Histone Methyltransferase, Antibiotic, Antifungal

Pemetrexed

T0189

Synonym: Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate

Target: DHFR, DNA/RNA Synthesis, Antifolate, Autophagy

Methyl methanesulfonate

T9985

Synonym:

Target: DNA Alkylation

Rac1 Inhibitor W56 acetate(1095179-01-3 free base)

Target: DNA Methyltransferase, DNA Alkylation

Cat No.	Product Name	Synonyms	Targets
T2A2537	Guanine	Pearl essence,Mearlmaid,2-Aminohypoxanthine	Others , DNA/RNA Synthesis , Endogenous Metabolite
	Guanine (2-Aminohypoxanthine) is a purine base that is a constituent of nucleotides occurring in nucleic acids.		Others , DNA/RNA Synthesis , Endogenous Metabolite
T22218	2'-Deoxyguanosine	Deoxyguanosine,Guanine deoxyriboside	Endogenous Metabolite
	2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by mol...		Endogenous Metabolite
T1709	2'-Deoxyinosine	Guanine deoxyriboside,Deoxyinosine	Others , Endogenous Metabolite
	2'-Deoxyinosine (Guanine deoxyriboside) inhibits the growth of human colon-carcinoma cell lines and is associated with purine nucleoside phosphorylase (PNP) deficiency.		Others , Endogenous Metabolite
T4715	2'-Deoxyguanosine monohydrate	Guanine-2'-deoxyriboside	Others , Endogenous Metabolite
	2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of D...		Others , Endogenous Metabolite
T19382	Isoguanine		Nucleoside Antimetabolite/Analog
	Isoguanine is a purine base that is an isomer of guanine. A building block in organic synthesis.		Nucleoside Antimetabolite/Analog
T13791	N2-methylguanine		DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial
	N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.		DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial
TN7185	7-Cyano-7-deazaguanine	7-CN-7-deazaG	Others
	7-Cyano-7-deazaguanine (7-CN-7-deazaG) is a marine derived natural products found in Streptomyces qinglanensis.		Others
T2218	8-Azaguanine	Azaguanine-8,SK 1150,NSC-749,SF-337	Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
	8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.
T19165	8-Hydroxyguanine	8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine	Endogenous Metabolite
	8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-H...		Endogenous Metabolite
T10194	7-Methylguanine		Others
	7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents and used as a probe of DNA–protein interactions and a key component of the DNA sequencing method.		Others
TJS0405	Lucidin	NSC 30546,Henine	Others
	1. Lucidin (NSC-30546) and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.		Others
T0665	Xanthine	2,6-Dihydroxypurine,Isoxanthine	Endogenous Metabolite , Adenosine Receptor
	Xanthine (Isoxanthine) is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most body tissues and fluids in...		Endogenous Metabolite , Adenosine Receptor
T5084	Xanthosine dihydrate		Others , Endogenous Metabolite
	Xanthosine is produced by guanine-free mutants of bacteria e.g. Bacillus subtilis, Aerobacter aerogenes. Xanthosine monophosphate is an intermediate in purine metabolism, formed from IMP, and forming GMP.		Others , Endogenous Metabolite
T6523	Guanosine	DL-Guanosine,Vernine,Guanozin	Endogenous Metabolite , HSV
	Guanosine (DL-Guanosine) is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism.		Endogenous Metabolite , HSV
T4746	Purine	7H-Imidazo(4,5-d)pyrimidine	Others , Endogenous Metabolite
	Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f...		Others , Endogenous Metabolite
T4839	Ac-Ala-OH	N-Acetylalanine,N-Acetyl-L-alanine	Others , Endogenous Metabolite
	Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro...		Others , Endogenous Metabolite
T38673	Sibiromycin
	Sibiromycin, a glycosylated pyrrolobenzodiazepines (PBDs) compound, is a naturally occurring and potent antitumor antibiotic. It exerts its activity by covalently binding to DNA in the minor groove at the NH2 of guanine.

Natural Products

Guanine

T2A2537

Synonym: Pearl essence,Mearlmaid,2-Aminohypoxanthine

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

2'-Deoxyguanosine

T22218

Synonym: Deoxyguanosine,Guanine deoxyriboside

Target: Endogenous Metabolite

2'-Deoxyinosine

T1709

Synonym: Guanine deoxyriboside,Deoxyinosine

Target: Others, Endogenous Metabolite

2'-Deoxyguanosine monohydrate

T4715

Synonym: Guanine-2'-deoxyriboside

Target: Others, Endogenous Metabolite

Isoguanine

T19382

Synonym:

Target: Nucleoside Antimetabolite/Analog

N2-methylguanine

T13791

Synonym:

Target: DNA/RNA Synthesis, Endogenous Metabolite, Antibacterial

7-Cyano-7-deazaguanine

TN7185

Synonym: 7-CN-7-deazaG

Target: Others

8-Azaguanine

T2218

Synonym: Azaguanine-8,SK 1150,NSC-749,SF-337

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

8-Hydroxyguanine

T19165

Synonym: 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine

Target: Endogenous Metabolite

Synonym: NSC 30546,Henine

Target: Others

Xanthine

T0665

Synonym: 2,6-Dihydroxypurine,Isoxanthine

Target: Endogenous Metabolite, Adenosine Receptor

Xanthosine dihydrate

T5084

Synonym:

Target: Others, Endogenous Metabolite

Guanosine

T6523

Synonym: DL-Guanosine,Vernine,Guanozin

Target: Endogenous Metabolite, HSV

Purine

T4746

Synonym: 7H-Imidazo(4,5-d)pyrimidine

Target: Others, Endogenous Metabolite

Ac-Ala-OH

T4839

Synonym: N-Acetylalanine,N-Acetyl-L-alanine

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-01429	SARS-CoV-2 Guanine-N7 methyltransferase Protein (His)	SARS-CoV-2	E. coli
	The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds...
TMPJ-00725	HGPRT Protein, Human, Recombinant (His)	Human	E. coli
	Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed pur...
TMPK-01308	TAG-72 Protein, Canine, Recombinant (His)	Canine	E. coli
	The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA...
TMPY-02802	GNG13 Protein, Human, Recombinant (His)	Human	E. coli
	GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducer...
TMPH-00313	TRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His)	Brugia malayi	E. coli
	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
TMPY-02805	GNGT1 Protein, Human, Recombinant (His)	Human	E. coli
	GNGT1 is a subunit of transducin. Heterotrimeric G proteins consist of alpha, beta, and gamma subunits. They are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-tra...
TMPH-02041	ARHGEF12 Protein, Human, Recombinant (His)	Human	E. coli
	ARHGEF12 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPH-02695	GNAO1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Stimulated by RGS14. The G(o) protein function is not clear.
TMPH-00270	GNAT2 Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that perfor...
TMPH-02693	GNAI2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhi...
TMPH-02694	GNG12 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GD...
TMPH-01209	DENND1A Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulat...
TMPH-00862	HTR1F Protein, Human, Recombinant (His & SUMO)	Human	in vitro E. coli expression system
	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guan...
TMPH-02313	RPGR Protein, Human, Recombinant (hFc)	Human	HEK293
	Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integ...
TMPH-02696	GNAQ Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent a...
TMPH-01663	GRM5 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Sign...
TMPJ-00872	MGMT Protein, Human, Recombinant (His)	Human	E. coli
	MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs al...
TMPH-02246	TGS1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and...
TMPH-00568	8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorpora...
TMPH-01207	DOCK8 Protein, Human, Recombinant (His)	Human	Yeast
	Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPH-02622	DOCK8 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPH-02675	GCGR Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g...
TMPH-00861	HTR1D Protein, Human, Recombinant (His & KSI)	Human	E. coli
	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding c...
TMPH-01382	GCGR Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g...
TMPH-02623	DOCK8 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPH-00860	HTR1D Protein, Human, Recombinant (hFc)	Human	HEK293
	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding c...
TMPH-01383	GCGR Protein, Human, Recombinant (His & Myc)	Human	HEK293
	G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g...
TMPY-03122	GBP2 Protein, Human, Recombinant (His)	Human	HEK293
	GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTP...
TMPY-03796	ARF3 Protein, Human, Recombinant (His)	Human	E. coli
	ARF3, also known as ADP-ribosylation factor 3, belongs to the RAS superfamily. Members of this family include ARF1, ARF2, ARF3, ARF4, ARF5 and ARF6. ARF3 gene is a member of the human ARF gene family. These genes encode ...
TMPH-00859	HTR1B Protein, Human, Recombinant (His)	Human	in vitro E. coli expression system
	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic...
TMPH-02697	GNA12 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF12/LARG). G...
TMPY-01203	RP2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	XRP2, also known as Protein XRP2 and RP2, is a member of the TBCC (tubulin cofactor C) family and contains one C-CAP/cofactor C-like domain. This protein is encoded by the RP2 gene in humans. XRP2 stimulates the GTPase a...
TMPH-01712	TRMT112 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylat...
TMPH-01631	DCP2 Protein, Human, Recombinant (His)	Human	E. coli
	Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the ...
TMPH-01801	NME2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Negativ...
TMPY-02977	PDE1C Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ...
TMPY-01661	METTL1 Protein, Human, Recombinant (His)	Human	E. coli
	tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. M...
TMPY-02399	TRF1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term...
TMPY-04443	NEK3 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	NEK3 (NIMA (never in mitosis gene a)-related expressed kinase 3), contains 1 protein kinase domain and is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. Members of the NEK family of...
TMPY-01479	SPG3A Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Atlastin-1, also known as Spastic paraplegia 3 protein A, Guanine nucleotide-binding protein 3, GTP-binding protein 3, GBP3, ATL1 and SPG3A, is a multi-pass membrane protein which belongs to theGBP family and atlastin...
TMPH-03734	Zaire ebolavirus (strain Mayinga-76) L Protein (His)	ZEBOV	E. coli
	RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras...
TMPH-02384	Lake Victoria marburgvirus (MARV) (strain Popp-67) L Protein (His & Myc)	MARV	E. coli
	RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras...
TMPH-03735	Zaire ebolavirus (strain Kikwit-95) L Protein (His & Myc)	ZEBOV	E. coli
	RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras...
TMPY-04755	AK3L1 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Adenylate kinase isoenzyme 4, mitochondrial, also known as ATP-AMP transphosphorylase, Adenylate kinase 3-like, AK4 and AK3L1, is a member theadenylate kinase family. AK4 / AK3L1 is localized to the mitochondrial matri...
TMPY-04469	AK3L1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Adenylate kinase isoenzyme 4, mitochondrial, also known as ATP-AMP transphosphorylase, Adenylate kinase 3-like, AK4 and AK3L1, is a member theadenylate kinase family. AK4 / AK3L1 is localized to the mitochondrial matri...
TMPY-06345	KRAS Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
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