formula

8-Oxoepiberberine (Oxyepiberberine) is an alkaloid metabolite in the plasma after oral administration of Zuojin formula. Zuojin formula is a traditional chinese medicine used to treat gastrointestinal disease.

LY3372689 (Formulaic Ia) is an oral, highly selective, CNS-permeable O-GlcNAcase (OGA) inhibitor. LY3372689 exerts a neuroprotective effect by inhibiting OGA enzymatic activity, increasing the O-GlcNAc glycosylation level of tau protein, and thereby reducing abnormal tau phosphorylation and the formation of neurofibrillary tangles. LY3372689 can be used in research on tau-related diseases, including Alzheimer’s disease.

(S)-6-methoxychroman-3-carboxylic acid is a synthetic compound with a molecular formula of C11H10O5. It is a member of the chroman family of compounds, which are characterized by a seven-membered ring with one oxygen and one carbon atom.

3-Methoxyaniline is an organic compound with the molecular formula CH3OC6H4NH2，3-Methoxyaniline is one of three possible structural isomers of the methoxy-containing aniline derivative.

λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group. It is employed across various applications for controlling a wide array of pests. As a neurotoxin, λ-Cyhalothrin acts on sodium channels in neuron membranes within the central nervous system.

D-(+)-Xylose (Wood sugar) is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucrose. Xylose is also found in mucopolysaccharides of connective tissue and sometimes in the urine. Xylose is the first sugar added to serine or threonine residues during proteoglycan type O-glycosylation. Therefore xylose is involved in the biosythetic pathways of most anionic polysaccharides such as heparan sulphate and chondroitin sulphate. In medicine, xylose is used to test for malabsorption by administering a xylose solution to the patient after fasting. If xylose is detected in the blood and/or urine within the next few hours, it has been absorbed by the intestines. Xylose is said to be one of eight sugars which are essential for human nutrition, the others being galactose, glucose, mannose, N-acetylglucosamine, N-acetylgalactosamine, fucose, and sialic acid. . Xylose in the urine is a biomarker for the consumption of apples and other fruits.

2-tert-Butyl-4-ethylphenol can be used in life science-related research, and its molecular formula is C12H18O.

Pentadecylic acid, a saturated fatty acid, consists of a 15-carbon straight chain commonly found in dairy products and some plants and animals, with the molecular formula C15H30O2. [It has a melting point of 52.4°C (126.3°F)] and is utilized in biochemical research and the synthesis of various compounds.

Nickel(II) oxide is the chemical compound with the formula NiO. It is the principal oxide of nickel.

Ethylene glycol is a diol used in the production of polyester fibres and as an antifreeze agent, widely applied in biochemical experiments and drug synthesis research.

TTK/PLK1-IN-1 (Formula I) is an inhibitor of threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1), with IC50 values of 7 nM and 72 nM, respectively. It regulates the spindle assembly checkpoint (SAC) and exhibits antitumor activity against triple-negative breast cancer (TNBC).

K-Ras-IN-1, a K-Ras inhibitor, is characterized by its chemical formula C20H19ClN4O2S and is also known as N-[(1S)-3-cyclopropyl-1-[(6-fluoro-1H-benzimidazol-2-yl)sulfanyl]-2-oxo-1-(phenylmethyl)propyl]-4-fluorobenzenesulfonamide (compound [18, dashboard 819041] in brackets).

Norbiotinamine hydrochloride, an alternative to biotin, is a water-soluble, white to off-white crystalline powder with the molecular formula C11H22ClN3O3S. It is commonly used in biochemical research as a biotin analog and exhibits similar binding properties to biotin in various assays and experiments.

CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.

KSQ-4279 (gentisate) (Compound Formula I) serves as an effective inhibitor of USP1 and a selective inhibitor of PARP1. This compound shows promise for use in cancer research.

Anticanceragent 257 (compound of formula (I)) is an anticancer agent that regulates Nur77 and Nurr1.

5-HT2A antagonist 3 (Formula (III)) functions as both an antagonist and an inverse agonist of the 5-HT2A receptor, exhibiting a pIC50 value of 8.7 and a pKi value of 9. It is applicable for research in neuroscience.

1-Acetylferrocene, an organoiron compound with the formula Fe, consists of ferrocene substituted by an acetyl group on one of the cyclopentadienyl rings. It is an orange, air-stable solid and is soluble in organic solvents.

KRAS G12D inhibitor 29 (Compound Formula (I)) is an orally active and selective inhibitor of KRASG12D. It effectively blocks KRASG12D-mediated downstream signaling pathways, thereby inhibiting the proliferation of tumor cells. This compound holds potential for research into cancers associated with KRASG12D mutations, such as pancreatic cancer, lung cancer, and colorectal cancer.

4-DTM-phenoxy-PEG4-CH2COOH (Formula 3) is a cleavable ADC linker that belongs to the PEG class, and is utilized in the synthesis of antibody-drug conjugates (ADCs).

Isometronidazole (RO-07-1502) is a chemical compound. The chemical compound is a derivative of the nitroimidazole family. Its molecular formula is C6H9N3O3. Isometronidazole can actually be used in the treatment of radiation therapy. The compound is known as a hypoxic cell sensitizer (radiosensitizer), increasing the efficacy of radiation treatment. Isometronidazole (RO-07-1502), a nitroimidazole derivative with the molecular formula C6H9N3O3, acts as a hypoxic cell sensitizer (radiosensitizer) in radiation therapy, enhancing the efficacy of the treatment.

Z-4105 (formula l) is a nootropic compound. It reverses the amnesia effects induced by electroconvulsive shock (ECS) and methylazoxymethanol acetate (MAM), thereby improving learning and memory functions. The compound enhances the activity of the brain's cholinergic system without affecting other neurotransmitter systems. Additionally, Z-4105 significantly alleviates neuropathic pain caused by chronic constriction injury (CCl) in rat sciatic nerve and spinal nerve ligament models. It is utilized in research on neuropathic pain and cognitive dysfunction.

Myt1-IN-6 (Compound formula (1)) is a highly selective inhibitor of the MYT1 kinase. It shows potential for research in RB1-deficient cancers, such as triple-negative breast cancer.

2,5-Epidithia-3,6-dioxopiperazine (Formula 15) is a derivative of Epidithiodioxopiperazine (ETP). It enhances cell permeability and restores the activity of 2-Cys-Prx, especially peroxidase II (PrxII), within stimulated cells. This compound inhibits PDGF-induced proliferation and migration of vascular smooth muscle cells while promoting VEGF-induced endothelial cell growth and movement. Furthermore, 2,5-Epidithia-3,6-dioxopiperazine effectively suppresses the proliferation, migration, and pulmonary metastasis of melanoma cells. It holds potential for research on vascular diseases such as hypertension, angina, and myocardial infarction.