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EED226-COOH, derived from EED226, serves as a ligand targeting the EED protein for PROTAC applications. It attaches to a VHL ligand through a linker, culminating in the formation of UNC6852, which specifically degrades PRC2[1].

EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.

PROTAC EED degrader-1, a PROTAC targeting EED (pKD = 9.02), is an inhibitor of polycomb repressive complex 2 (PRC2) with a pIC50 of 8.17.

PROTAC EED degrader-2 is a PROTAC targeting EED (pKD of 9.27) and an inhibitor of polycomb repressive complex 2 (PRC2) with a pIC50 of 8.11.

EEDi-5285, an orally active and highly potent inhibitor targeting embryonic ectoderm development (EED) protein, exhibits anti-cancer activity. It demonstrates exceptional efficacy with an IC50 value of 0.2 nM, indicating robust binding affinity to the EED protein.

MAK683 hydrochloride embryonic ectodermal development (EED) inhibitor, also a potent PRC2 inhibitor, blocked cancer cell proliferation (IC50=1.014nM), with IC50 values of 59, 26, and 89 nM measured in EED Alphascreen, ELISA, and LC-MS assays, respectively.

MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).

UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.

Boc-GABA-OH serves as a PROTAC linker essential for synthesizing UNC6852, an EED-targeted PROTAC[1].

EED-IN-3 is an orally active inhibitor of EED. It effectively binds with EED (IC50 = 0.62 μM) to inhibit PRC2 and reduces H3K27me3 levels. EED-IN-3 selectively inhibits PC3 cells with an IC50 of 3.69 μM and significantly suppresses colony formation and migration. This compound is useful for prostate cancer research.

EED ligand 1 is a highly versatile, potent, and effective inhibitor that specifically targets the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase.

Cottonseed oil, a cooking oil extracted from the seeds of cotton plants, has been considered the most insecticidal of vegetable oils.

Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties.

Aflatoxin Total in cotton seed (Standard) is a reference material for the determination of total aflatoxins (including B1, B2, G1 and G2) in food and feed, which are secondary metabolites produced by Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are highly toxic, extremely harmful to organs such as liver and kidney, and are class I carcinogens.

EEDi-5285 TFA(2488952-40-3 Free base) is a potent and orally active small molecule inhibitor of embryonic ectodermal development (EED) with an IC50 value of 0.2 nM and excellent pharmacokinetics.

EEDi-5273 is a highly potent and orally efficacious inhibitor of EED, with an approximate IC50 value of 0.2 nM. This compound exhibits exceptional activity, capable of achieving complete and persistent regression of tumors.

Rheediaxanthone A is a useful organic compound for research related to life sciences and the catalog number is T124238.

Antifeedant agent 1 functions as a carboxylesterase inhibitor that controls insect pests by inhibiting their feeding, with an EC50 of 0.038 mg/mL. It is applicable in the research of pest control.

EEDQ is an irreversible dopamine-receptor antagonist.EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.

Z-LEED-FMK is a chemical compound that acts as an inhibitor for caspase-13 and caspase-4. Additionally, it impedes caspase-1 processing in S. typhimurium-infected macrophages [1] [2].

Borage oil(from Borago officinalis seeds)is a biochemical reagent.

Coix Seed Oil Reference Extract (Standard) is a reference standard of Coix Seed Oil Reference Extract intended for quantitative analysis, quality control, and related biochemical research applications.

Pollen extract, ragweed, is an allergen derived from ragweed samples and is utilized in allergenic research.

Coix Seed oil is a natural product that can be used in related research in the field of life sciences. Its product number is TN8906.