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Search Results for " diabete "

Targets

12

Compounds

5

Natural Products

Cat No. Product Name Synonyms Targets
T9491 Pyraclostrobin Antibacterial , Antifungal
Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.
T2055 WS3 EGFR , IκB/IKK
WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.
T15432 GSK256073 GPR , Others
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inh...
T6237 Trelagliptin SYR-472 Proteasome , DPP-4
Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.
T9098 DMG-PEG 2000 DMG-PEG2000 Others
DMG-PEG 2000 (DMG-PEG2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles. Formulations containing DMG-PEG 2000 have been used in the development of lipid...
T0214 Pioglitazone U 72107 Ferroptosis , PPAR
Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury.
T7661 SD-169 SD 169 p38 MAPK
SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.
T20029 Buformin hydrochloride NSC528218,NSC-528218,NSC 528218 AMPK
Buformin hydrochloride (NSC-528218) is a potent AMPK activator,an oral antidiabetic drug of the biguanide class. Buformin delays the absorption of glucose from the gastrointestinal tract increases insulin sensitivity and...
T2296 Trelagliptin succinate SYR-472 succinate,SYR472 Proteasome , DPP-4
Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (T2D).
T15656 KGA-2727 SGLT
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA...
T74980 SPAA-52
SPAA-52 is an orally active, competitive and reversible low-molecular-weight protein tyrosine phosphatase ( LMW-PTP ) inhibitor ( IC 50 =4 nM, K i =1.2 nM). SPAA-52 can be used in diabete research [1] .
T62019 Sheng Gelieting
Sheng Gelieting (CGT-8012) is a inhibitor of dipeptidy peptidase-IV enzyme (DP-IV) with an IC 50 value of 87 nM. Sheng Gelieting can be used for researching to the dipeptidy peptidase-IV enzyme, such as the diabetes, par...
Cat No. Product Name Synonyms Targets
T4733 Sucrose D(+)-Sucrose,D-(+)-Saccharose Others , Endogenous Metabolite
Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.
T8319 Butyl isobutyl phthalate ButylIsobutylPhthalate Glucosidase
Butyl isobutyl phthalate (ButylIsobutylPhthalate) is a non-competitive α-glucosidase inhibitor(IC50 :38 μM),it shows a hypoglycemic effect
TMS0719 Sequoyitol 5-O-Methyl-Myo-Inositol Others
Sequoyitol (5-O-Methyl-Myo-Inositol), a methyl derivative of inositol, is often used to treat diabetes.
T2869 Emodin Frangula emodin SARS-CoV , Casein Kinase , Autophagy
Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.
T1135 Vitamin D3 Cholecalciferol,Colecalciferol Endogenous Metabolite
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
TargetMol