TO-PRO 1

TO-PRO 1, a DNA-binding fluorochrome, is attached to the surface of Feraheme (FH) nanoparticles (NP) to create a fluorochrome-functionalized NP. It binds DNA via intercalation and serves as a crucial fluorochrome for identifying necrotic cells [1]. For storage, it is essential to protect it from light.

Z-Gly-Pro-Arg-AMC hydrochloride is a synthetic peptide that is often used as a trypsin and histone K fluorescent substrate to measure enzyme activity, which fluoresces when the enzyme is cleaved from the peptide.

Z-Gly-Pro-Arg-4MβNA is a thrombin substrate that, when cleaved by thrombin, releases 4-methoxy-2-naphthylamine (4MβNA). The liberated 4MβNA reacts with 5-nitrosalicylaldehyde, forming an insoluble yellow fluorescent product, which indicates the site of thrombin activity [1].

Ala-Phe-Pro-pNA, a chromogenic substrate of tripeptidyl peptidase, can be utilized to assess tripeptidyl peptidase activity [1].

Sar-Pro-Arg-pNA, a chromogenic substrate of α-thrombin, can be used to test α-thrombin activity [1].

Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) serves as a chromogenic substrate for the peptidylprolyl isomerase Pin1. It is utilized to assess Pin1's inhibition by target compounds and to evaluate its catalytic activity, among other applications [1] [2].