rutin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0795	Rutin	Quercetin 3-O-rutinoside,Rutoside	Beta Amyloid , Prostaglandin Receptor , Autophagy
	Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.		Beta Amyloid , Prostaglandin Receptor , Autophagy
T22417	Rutin hydrate	Rutoside,Sophorin,Quercetin-3-O-rutinoside	Beta Amyloid , Others , Autophagy
	Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.		Beta Amyloid , Others , Autophagy
T77201	Rutin trihydrate
	Rutin (Rutoside) trihydrate, a natural flavonoid glycoside, exhibits multifaceted therapeutic properties, including antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic activities. Additionally, it has de...
T8636	Ibrutinib deacryloylpiperidine	IBT4A,5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine	BTK
	Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.		BTK
T5407	Branebrutinib	BMS986195	BTK
	Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family (IC50 <1 nM for BTK).		BTK
T9408	N-piperidine Ibrutinib		BTK
	N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as S...		BTK
T16730	Remibrutinib		BTK
	Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticar...		BTK
TQ0236	Tirabrutinib	ONO-4059,GS-4059,Velexbru	BTK
	Tirabrutinib (GS-4059) (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and ...		BTK
T12542	Rilzabrutinib	PRN1008	EGFR , Others , HER , BTK
	Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK)(IC50 of 1.3 nM).		EGFR , Others , HER , BTK
T12311	Tirabrutinib hydrochloride	ONO-4059 (hydrochloride),GS-4059 (hydrochloride)	BTK
	Tirabrutinib hydrochloride (GS-4059 (hydrochloride)) is a selective and novelBTK with IC50 2.2 nm inhibitor.		BTK
T13447	(R)-Zanubrutinib	(R)-BGB-3111	BTK
	(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).		BTK
T3626	Acalabrutinib	ACP-196	BTK
	Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre...		BTK
T1835	Ibrutinib	PCI-32765	Tyrosine Kinases , Src , BTK , Ligands for Target Protein for PROTAC
	Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.
T33479	Monoxerutin	Z 12007
	Monoxerutin is a flavonol.
T0772	Troxerutin	Trihydroxyethylrutin	NOD-like Receptor (NLR)
	Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.		NOD-like Receptor (NLR)
TQ0039	(±)-Zanubrutinib	(±)-BGB-3111	BTK
	(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability, achieving higher exposure and more complete target inhibi.		BTK
TQ0242	Fenebrutinib	GDC-0853	BTK
	Fenebrutinib (GDC-0853) is a selective and noncovalent Btk inhibitor (Ki: 0.91 nM).		BTK
T17220	Vecabrutinib	SNS-062	Tyrosine Kinases , BTK
	Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.		Tyrosine Kinases , BTK
T36287	Pirtobrutinib		BTK
	Pirtobrutinib (LOXO-305) is an advanced BTK inhibitor that displays high selectivity and operates through a non-covalent mechanism. This compound effectively inhibits various BTK C481 substitution mutations, leading to t...		BTK
T12152	N-piperidine Ibrutinib hydrochloride		BTK
	N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor, a BTK ligand, inhibits WT BTK and C481S BTK, which can be used to synthesize a range of PROTAC molecules.N-piperidine Ibrutinib hydrochloride has potential ...		BTK