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Search Results for " npy "

20

Compounds

Cat No. Product Name Synonyms Targets
T23087 NPY 5RA972 Neuropeptide Y Receptor
neuropeptide Y Y5 receptor antagonist
TP2194L Neuropeptide Y (scrambled) Acetate Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate Others
Neuropeptide Y (scrambled) Acetate (Pro-Neuropeptide Y (scrambled) Acetate) is a scrambled peptide of Neuropeptide Y that has been implicated in Alzheimer's disease (AD) and may have neuroprotective effects.
T83677 Neuropeptide Y (porcine, bovine) TFA NPY (porcine, bovine)
Neuropeptide Y (NPY), a neuropeptide, plays roles in regulating appetite, vasoconstriction, cardiac contractility, and intestinal secretion, acting as an agonist for NPY receptors Y1, Y2, and Y5. Expressed ubiquitously, ...
T71749 SF-22 Neuropeptide Y Receptor
SF-22 is a neuropeptide Y receptor (Y2R) antagonist that crosses the blood-brain barrier and has potential anti-inflammatory activity for the study of diseases associated with neurological disorders.
T23094 NTNCB hydrochloride Others , Neuropeptide Y Receptor
NTNCB hydrochloride is an antagonist of neuropeptide Y (NPY) Y5 receptor.
TQ0286 MK-0557 Neuropeptide Y Receptor
MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).
TP2206 [Leu31,Pro34]-Neuropeptide Y (porcine) Neuropeptide Y Receptor
High affinity neuropeptide Y Y1 receptor agonist
T10539 BIBO3304 TFA Neuropeptide Y Receptor
BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 receptor).
T8963 CYM2503 Neuropeptide Y Receptor
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthosteric galanin binding site of the receptor (as measured by ...
T5455 HT-2157 SNAP37889,SNAP-37889 Neuropeptide Y Receptor
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
T17222 Velneperit S2367 Neuropeptide Y Receptor
Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
T5587 CGP71683 hydrochloride CGP71683A Neuropeptide Y Receptor
CGP71683 hydrochloride (CGP71683A) is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
TP1380 Galanin (1-16), mouse, porcine, rat Neuropeptide Y Receptor
Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons.
T1997 JNJ-31020028 JNJ 31020028 Neuropeptide Y Receptor
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
TP1059 Peptide YY (PYY) (3-36), human Peptide YY (3-36) Neuropeptide Y Receptor
Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.
T8456 GALNON Neuropeptide Y Receptor
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
T12895 SHA 68 Neuropeptide Y Receptor
SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR)(NPSR Asn107 and NPSR Ile107 with IC50s of 22.0 and 23.8 nM, respectively).
T4445 Tolfenpyrad Antibacterial
Tolfenpyrad is an effective insecticide[1], used against pests that are resistant to existing insecticides such as organophosphates and carbamates.[2]
T0435 Sulfinpyrazone (+/-)-Sulfinpyrazone,G-28315,NSC 75925 COX
Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
T4446 Tebufenpyrad Pyranica,MK239,Comanche Mitochondrial Metabolism
Tebufenpyrad (Comanche) (mitochondrial complex-1 inhibitors) is an agro-chemically important acaricide that functions like the known mitochondrial toxicant rotenone.
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TargetMol