CDP

Cytidine 5'-diphosphate trisodium salt (CDP) catalyzes the production of Cytidine triphosphate (CTP) for DNA and RNA synthesis by transferring a phosphoryl group from ATP to cytidine monophosphate (CMP) through the action of uridine monophosphate kinase (UMPK).

Cytidine 5′-diphosphat (5'-CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK).

CDP-β-S (Cytidine-5'-O-(2-thiodiphosphate)) trisodium salt is a non-hydrolyzable analog of CDP (Cytidine Diphosphate) with antioxidant and free radical scavenging properties.

CDP-840 (GR259653X) is a potent, selective, and orally active phosphodiesterase IV (PDE IV) inhibitor that specifically inhibits antigen-induced early and late phase bronchoconstriction in conscious squirrel monkeys [1].

CDP-Star is a luminescent substrate for 1,2-dioxetane and a substrate for alkaline phosphatase.CDP-Star can be used for in vivo imaging by detecting mRNA on Northern blot.

CDP-484 is an inhibitory antibody that can be used in life science related research.

2'-Deoxy-3',5'-CDP (pdCp) is a monomer used in nucleotide synthesis.

2'-F-CDP is a nucleotide analog that can be utilized in the synthesis of oligonucleotides.

16:0 CDP DG ammonium is a type of lipid nucleotide.

CDP-Ribitol 2TEA (3506-17-0 Free base) is the di- and triethanolamine salt form of cytidine diphosphate ribitol (CDP-Ribitol) and can serve as a substrate or intermediate for in vitro studies of glycosyltransferase reactions. CDP-Ribitol 2TEA (3506-17-0 Free base) can be used in studies of glycoprotein synthesis, glycosylation modifications, and related metabolic pathways.

Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.

Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders. Exogenous administration of citicoline to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.

Cytidine 5'-diphosphate disodium (CDP sodium salt) produces CTP to support DNA and RNA biosynthesis and ribonucleotide reductase to produce dCMP.

Romosozumab (AMG-785) is a humanized monoclonal antibody that binds and inhibits sclerostin, increasing bone formation and decreasing bone resorption.Romosozumab is used in the study of postmenopausal osteoporosis.

Gemtuzumab(CMA-676) is a monoclonal antibody directed against the CD33 antigen and consists of a recombinant humanized IgG4 antibody.Gemtuzumab can be used to synthesize Gemtuzumab ozogamicin, an antibody coupled compound (ADC) Gemtuzumab is used in the study of acute myeloid leukemia.

Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.

Zaurategrast ethyl ester is the ethyl ester prodrug of CT7758 and is an α4β1/α4β7 integrin antagonist. It is used for the treatment of inflammatory and autoimmune disorders.

Olokizumab (CDP-6038) is a humanized anti-IL-6 monoclonal antibody that selectively blocks the final assembly of the IL-6 signaling complex for the study of rheumatoid arthritis (RA).

Dapirolizumab pegol (CDP 7657), a monoclonal antibody of the Fab'-IgG-κ class, targets CD40LG/TNFSF5 and is conjugated with a pegol moiety. The antibody was initially cloned from the Norway rat (Rattus norvegicus).

Cytidine-5'-O-(2-thiodiphosphate) (CDP-β-S), a non-hydrolyzable derivative of CDP exhibiting antioxidant activity, effectively scavenges free radicals as evidenced by its performance in the Trolox equivalent absorbance capacity (TEAC) assay at concentrations between 5 and 20 µM.

Alacizumab pegol (CDP-791), a pegylated antibody fragment targeting KDR, is utilized in cancer research [1].

Senlizumab is a human monoclonal antibody expressed in CHO cells that specifically targets TNFSF2 (Tumor Necrosis Factor-alpha, TNF-α). It features a huIgG4SP heavy chain and a huκ light chain, with a predicted molecular weight of 146.9 kDa. Senlizumab neutralizes the biological activity of TNF-α by blocking its interaction with TNF receptors, thereby inhibiting downstream pro-inflammatory signaling pathways. It serves as a valuable tool for research into autoimmune and inflammatory diseases. The recommended isotype control is Human IgG4 kappa, Isotype Control (HY-P99003).

1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium (18:1 CDP DG) is a derivative of diacylglycerol.

CpCDPK1/TgCDPK1-IN-3 is a dual inhibitor of CpCDPK1 and TgCDPK1 with an IC50 of 0.003 µM for CpCDPK1 and 0.0036 µM for TgCDPK1. CpCDPK1/TgCDPK1-IN-3 can be used to study infections associated with diseases such as Toxoplasma, Cryptosporidium and Cryptosporidium.