T3512 |
S49076 HCl
|
1265966-31-1
|
98%
|
|
S49076 is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream...
|
TN4474 |
Macrocarpal B
|
142698-60-0
|
98%
|
|
The intestinal absorption of M-A, Macrocarpal B, and Cy-C was passive diffusion as the dominating process and Cy-C was partly ATP-dependent.
|
T15384 |
Glesatinib
|
936694-12-1
|
98%
|
|
Glesatinib is an orally active and potent dual inhibitor of MET/SMO. Glesatinib is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multi...
|
T12418 |
PF-04217903 phenolsulfonate
|
1159490-85-3
|
98%
|
|
PF-04217903 phenolsulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).
|
T10654 |
C-Met-IN-2
|
1635406-73-3
|
98%
|
|
c-Met-IN-2 is a selective and orally available c-Met inhibitor (IC50: 0.6 nM) with antitumor activity.
|
T15383 |
Glesatinib hydrochloride
|
1123838-51-6
|
98%
|
|
Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO. Glesatinib hydrochloride is also a tyrosine kinase inhibitor. It antagonizes P...
|
T10653 |
C-met-IN-1
|
2084836-84-8
|
98%
|
|
c-met-IN-1 is a potent and selective c-Met inhibitor (IC50: 1.1 nM) with antitumor activity.
|
T12417 |
PF-04217903 methanesulfonate
|
956906-93-7
|
98%
|
|
PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).
|
T37596 |
Terevalefim
|
1070881-42-3
|
98%
|
|
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
|
T11162 |
EGFR-IN-8
|
2407957-87-1
|
98%
|
|
EGFR-IN-8 can be a promising candidate for further development to target EGFR TKI-resistant NSCLC. EGFR-IN-8 is a dual EGFR and c-Met inhibitor.
|
T63313 |
Unecritinib
|
1418026-92-2
|
98%
|
|
Unecritinib (TQ-B3101) is a potent, orally active, highly potent, blood-brain barrier permeable and low toxic inhibitor of EGFR tyrosine kinase with antitumor ac...
|
T7787 |
BMS817378
|
1174161-69-3
|
98%
|
|
BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).
|
T4260 |
Capmatinib 2HCl
|
1197376-85-4
|
98%
|
|
INCB-28060(free base) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.INCB28060 exhibits picomolar enzymatic potency and is highl...
|
T5414 |
Glumetinib
|
1642581-63-2
|
98%
|
|
Glumetinib (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).
|
T2185 |
L-Ascorbic acid 2-phosphate trisodium
|
66170-10-3
|
98%
|
|
L-Ascorbic acid 2-phosphate (AA2P) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.
|
T2208 |
Bacitracin Zinc
|
1405-89-6
|
98%
|
|
Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from M...
|
T5677 |
SAR125884 hydrochlorid (1116743-46-4(free base))
|
T5677
|
98%
|
|
SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 nM).
|
T67859 |
N'-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-3-phenylpropanohydrazide
|
299405-67-7
|
98%
|
|
N'-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-3-phenylpropanohydrazide is a c-Met kinase inhibitor.
|
T39507L |
Fosgonimeton acetate
|
|
98%
|
|
Fosgonimeton aceate is an agonist of hepatocyte growth factor (HGF).
|
T5164 |
Cabozantinib hydrochloride
|
1817759-42-4
|
98%
|
|
Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
|