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CaSR

The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor which senses extracellular levels of calcium ion. It is primarily expressed in the parathyroid gland and the renal tubules of the kidney.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T79023 CaSR antagonist-1 1219811-83-2 98%
CaSR antagonist-1
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation o...
T10666 Calhex 231 hydrochloride 2387505-78-2 98%
Calhex 231 hydrochloride
Calhex 231 hydrochloride is a CaSR inhibitor with the potential for diabetic cardiomyopathy treatment. It blocks Ca2+-induced accumulation of [3H]inositol phosph...
T2406 Cinacalcet hydrochloride 364782-34-3 99.9%
Cinacalcet hydrochloride
Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-s...
T15261 Evocalcet 870964-67-3 99.83%
Evocalcet
Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).
T8403 Cinacalcet 226256-56-0 99.82%
Cinacalcet
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .
T34385 Ronacaleret HCl 702686-96-2 99.58%
Ronacaleret HCl
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.
T3802 Ligustroflavone 260413-62-5 99.51%
Ligustroflavone
Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.
T13918 Tecalcet Hydrochloride 177172-49-5 99.44%
Tecalcet Hydrochloride
Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the ...
T4967 NPS-2143 hydrochloride 324523-20-8 99.22%
NPS-2143 hydrochloride
NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.
T29067L Upacicalcet HCl 98.56%
Upacicalcet HCl
Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors ...
T1730 NPS-2143 284035-33-2 98.24%
NPS-2143
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
TP1236 Etelcalcetide hydrochloride 1334237-71-6 100%
Etelcalcetide hydrochloride
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that acts as an allosteric modulator of the calcium-sensing receptor (CaSR), effective...
T1641 Strontium ranelate 135459-87-9 100%
Strontium ranelate
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoar...
T29541 AC265347 1253901-26-6 100%
AC265347
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour grow...
T22795 Gadolinium chloride 10138-52-0
Gadolinium chloride
Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist
T12846 SB-423562 351490-27-2 98%
SB-423562
SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.
T23401 Strontium chloride 10476-85-4 98%
Strontium chloride
Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.
T40363 Poly-D-lysine hydrobromide (MW 30000-70000) 27964-99-4 98%
Poly-D-lysine hydrobromide (MW 30000-70000)
Poly-D-lysine hydrobromide (MW 30000-70000)(Poly-D-lysine HBr) is an orally available peptide CaSR agonist that removes proteinase K-resistant PrP from prion-inf...
CaSR antagonist-1
T79023
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation o...
Calhex 231 hydrochloride
T10666
Calhex 231 hydrochloride is a CaSR inhibitor with the potential for diabetic cardiomyopathy treatment. It blocks Ca2+-induced accumulation of [3H]inositol phosph...
Cinacalcet hydrochloride
T2406
Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-s...
Evocalcet
T15261
Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).
Cinacalcet
T8403
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .
Ronacaleret HCl
T34385
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.
Ligustroflavone
T3802
Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.
Tecalcet Hydrochloride
T13918
Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the ...
NPS-2143 hydrochloride
T4967
NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.
Upacicalcet HCl
T29067L
Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors ...
NPS-2143
T1730
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
Etelcalcetide hydrochloride
TP1236
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that acts as an allosteric modulator of the calcium-sensing receptor (CaSR), effective...
Strontium ranelate
T1641
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoar...
AC265347
T29541
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour grow...
Gadolinium chloride
T22795
Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist
SB-423562
T12846
SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.
Strontium chloride
T23401
Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.
Poly-D-lysine hydrobromide (MW 30000-70000)
T40363
Poly-D-lysine hydrobromide (MW 30000-70000)(Poly-D-lysine HBr) is an orally available peptide CaSR agonist that removes proteinase K-resistant PrP from prion-inf...
TargetMol