Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • PDE
    (29)
  • TNF
    (3)
  • Apoptosis
    (2)
  • IL Receptor
    (2)
  • Antibacterial
    (1)
  • Antioxidant
    (1)
  • HIV Protease
    (1)
  • Leukotriene Receptor
    (1)
  • NF-κB
    (1)
  • Others
    (32)
Filter
Search Result
Results for "

phosphodiesterase 4 inhibitor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    73
    TargetMol | Inhibitors_Agonists
  • Natural Products
    7
    TargetMol | Natural_Products
  • Isotope Products
    4
    TargetMol | Isotope_Products
phosphodiesterase 4 inhibitor
T36018346440-86-6
Phosphodiesterase 4 (PDE4) inhibitor is an inhibitor of PDE4 with an IC50 value of 0.10 μM for the human recombinant enzyme.
  • Inquiry Price
6-8 weeks
Size
QTY
PDE IV-IN-1
T10201225100-12-9In house
PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound for the study of depression.
  • Inquiry Price
6-8 weeks
Size
QTY
TargetMol | Inhibitor Sale
Oglemilast
GRC 3886
T16379778576-62-8In house
Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
HT-0712
IPL-455903, IPL455903, IPL 455903, HT0712
T27557617720-02-2In house
HT-0712 is a phosphodiesterase 4 (PDE4) inhibitor.
  • Inquiry Price
3-6 months
Size
QTY
AWD 12-281
GW 842470, GSK-842470, GSK 842470, AWD12-281, AWD-12-281
T30232257892-33-4In house
AWD 12-281 is a selective phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory and bronchodilator activity used in the study of chronic obstructive pulmonary disease (COPD).
  • Inquiry Price
6-8 weeks
Size
QTY
Filaminast
Way-pda-641, WAY-PDA 641, UNII-CDD69JC61J, CDD69JC61J
T31792141184-34-1In house
Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.
  • Inquiry Price
6-8weeks
Size
QTY
TargetMol | Inhibitor Sale
MK-0873
MK 0873, MK0873
T33422500355-52-2In house
MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor.
  • Inquiry Price
6-8weeks
Size
QTY
TargetMol | Inhibitor Sale
Tanimilast
CHF-6001
T386251239278-59-1In house
Tanimilast (CHF-6001) is a novel, potent, and selective phosphodiesterase 4 inhibitor with an IC50 value of 0.026 ± 0.006 nM. It exhibits potent anti-inflammatory activity and is indicated for topical use in the lungs. Tanimilast was studied for its effects on obstructive lung disease.
  • Inquiry Price
6-8weeks
Size
QTY
Dovramilast
CC-11050
T63056340019-69-4In house
Dovramilast (CC-11050) is an orally active phosphodiesterase 4 (PDE4) inhibitor that reduces the production of pro-inflammatory mediators and cytokines. Dovramilast is used in the study of Mycobacterium tuberculosis infections and lupus erythematosus.
  • Inquiry Price
6-8 weeks
Size
QTY
uk-50001
T67815857900-47-1In house
uk-50001 is a phosphodiesterase (PDE) 4 inhibitor that can be used for many diseases, especially inflammation, allergies, respiratory diseases, disorders and conditions and wounds.
  • Inquiry Price
6-8weeks
Size
QTY
TargetMol | Inhibitor Sale
Parogrelil Free Base
NM-702 Free Base
T70793139145-27-0In house
Parogrelil Free Base (NM-702 Free Base) is a selective phosphodiesterase 3 inhibitor with bronchodilatory and anti-inflammatory effects, inhibits leukotriene (LT)D(4) and histamine-induced constriction of isolated guinea pig tracheal strips, and can be used in the study of bronchial asthma.
  • Inquiry Price
6-8 weeks
Size
QTY
Roflumilast
BYK 20869, BY 217, B9302-107, APTA 2217
T1024162401-32-3
Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling.
  • Inquiry Price
Size
QTY
Apremilast
CC-10004
T2923608141-41-9
Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.
  • Inquiry Price
Size
QTY
Crisaborole
PF-06930164, AN-2728
T4285906673-24-3
Crisaborole (AN-2728) is a phosphodiesterase 4 inhibitor.
  • Inquiry Price
Size
QTY
Drotaverine hydrochloride
T8787985-12-6
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally related to papaverine
  • Inquiry Price
Size
QTY
Difamilast
T27172937782-05-3
Difamilast is an inhibitor of phosphodiesterase IV.
  • Inquiry Price
6-8 weeks
Size
QTY
Pinoresinol 4-O-β-D-glucopyranoside
(+)-pinor, (+)-pinoresinol-β-D-glucoside; (+)-pinor, (+)-pinoresinol-β-D-glucoside
T4S079269251-96-3
(+)-pinoresinol-β-D-glucoside; (+)-pinor is the major active furanoid lignan in Lianxian. It shows antioxidant, hypotensive and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory activities.
  • Inquiry Price
Size
QTY
Rolipram
ZK 62711, (R,S)-Rolipram
T664461413-54-5
Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.
  • Inquiry Price
Size
QTY
RS-25344 hydrochloride
T23256152815-28-6
RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
FCPR03
T393411917347-65-9
FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepressant-like effects.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Lotamilast
E6005, RVT-501
T3987947620-48-6
Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
RS-25344
T9239152814-89-6
RS-25344 is a potent and selective phosphodiesterase (PDE) 4 inhibitor. It inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
GSK256066 Trifluoroacetate
GSK 256066 Trifluoroacetate, GSK256066 (2,2,2-trifluoroacetic acid)
T114831415560-64-3
GSK 256066 Trifluoroacetate is a selective and high-affinity phosphodiesterase 4 (PDE) inhibitor (IC50: 3.2 pM for PDE4B). It can be used for the treatment of chronic obstructive pulmonary disease.
  • Inquiry Price
1-2 weeks
Size
QTY
L791943
T11810192767-01-4
L791943 is a selective, potent) inhibitor of Phosphodiesterase-4 (PDE4,IC50 of 4.2 nM).
  • Inquiry Price
8-10 weeks
Size
QTY