Search Result

Search Results for " neuroblastoma "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T16350	NSC-87877		Apoptosis , Phosphatase
	NSC-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (IC50=0.318 μM, 0.355 μM of shp2 and shp1, respectively).It also inhibits dual-specificity phosphatase 26 (DUSP26).		Apoptosis , Phosphatase
T1841	UNC0379		Histone Methyltransferase
	UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.		Histone Methyltransferase
T6911	NSC-87877 disodium	NSC87877	Apoptosis , Phosphatase
	NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduce...		Apoptosis , Phosphatase
T8596	Ceefourin 1		MRP
	Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.		MRP
T12165	NAChR agonist 1	DUN71755	AChR
	nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.		AChR
T11908	LY2365109 hydrochloride		GlyT
	LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.		GlyT
T6609	NMS-E973		HSP
	NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.		HSP
T6708	Tolcapone	Tasmar,Ro 40-7592	Apoptosis , Beta Amyloid , Transferase
	Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa.		Apoptosis , Beta Amyloid , Transferase
T0412	Idebenone	CV-2619	Apoptosis , Antioxidant , Mitochondrial Metabolism
	Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).		Apoptosis , Antioxidant , Mitochondrial Metabolism
T9240	Sulfopin	Acetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(tetrahydro-1,1-dioxido-3-thienyl)-	Others
	Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.		Others
T12134	MYCMI-6	NSC354961	Apoptosis , c-Myc
	MYCMI-6 (NSC-354961) is a potent and selective inhibitor of endogenous MYC:MAX protein interactions，reduces proliferation and induces massive apoptosis in tumor tissue from a MYC-driven xenograft tumor model without seve...		Apoptosis , c-Myc
T1967	AZD-3463	ALK/IGF1R inhibitor	Apoptosis , IGF-1R , ALK , Autophagy
	AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.		Apoptosis , IGF-1R , ALK , Autophagy
T6611	NSC697923	2-[(4-methylphenyl)sulfonyl]-5-nitrofuran	E1/E2/E3 Enzyme
	NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct me...		E1/E2/E3 Enzyme
T3061	Lorlatinib	PF-6463922,PF-06463922,Loratinib	Apoptosis , Tyrosine Kinases , ROS , ALK , ROS Kinase
	Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity.		Apoptosis , Tyrosine Kinases , ROS , ALK , ROS Kinase
T29541	AC265347	AC-265347	CaSR
	AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to stud...		CaSR
T77495	WDR5-IN-6		JAK
	WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6 exhibits potent antitumor activity and inhibits cell proliferati...		JAK
T3203	Methyl 13-cis-4-Oxoretinoate	13-cis-4-Oxo-retinoic acid Methyl Ester,4-Keto 13-cis-Retinoic Acid Methyl Ester	Others
	Methyl 13-cis-4-Oxoretinoate (13-cis-4-Oxo-retinoic acid Methyl Ester) is a retinoic acid metabolite in neuroblastoma.		Others
T9068	Cucurbit[7]uril		Others
	Cucurbit[7]uril is an emerging candidate for pharmaceutical excipients.Cucurbit[7]uril enhances photosensitization of porphyrins in Neuroblastoma cells		Others
T4436	RO1138452	CAY10441	Others , Prostaglandin Receptor
	RO1138452 (CAY10441) is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cycli...		Others , Prostaglandin Receptor
T40363	Poly-D-lysine hydrobromide (MW 30000-70000)	Poly-D-lysine HBr (MW 30000-70000)	CaSR
	Poly-D-lysine hydrobromide (MW 30000-70000)(Poly-D-lysine HBr) is an orally available peptide CaSR agonist that removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells.		CaSR
T3690	A-740003	A 740003	P2X Receptor
	A-740003 (A 740003) is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human). It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuro...		P2X Receptor
T77448	Naxitamab	Naxitamab-gqgk,Humanized 3F8,Hu3F8	Others
	Naxitamab (Hu3F8) is a humanized monoclonal antibody against GD2 (hu3F8). Naxitamab has antitumor activity and can be used to study neuroblastoma, osteosarcoma, and other GD2-positive cancers.		Others
T77332	TV 3279		BCL , PKC
	TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SOD, and to block the nuclear translocation of the pro-apopto...		BCL , PKC
T16703	Quarfloxin	CX-3543	DNA/RNA Synthesis
	Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...		DNA/RNA Synthesis
T16550	PKR-IN-C16		Others
	PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the A...		Others
T1758	ABT-751	E7010	Microtubule Associated , Autophagy
	ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.		Microtubule Associated , Autophagy
T77651	Tubulin polymerization-IN-47		Microtubule Associated
	Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 an...		Microtubule Associated
T41180	JQAD1		Epigenetic Reader Domain
	JQAD1 is a potent and selective histone acetyltransferase EP300 degrader (PROTAC®; DC50≤ 31.6 nM); comprises an EP300 inhibitor, A485, joined by a linker to a cereblon E3 ligase ligand. JQAD1 brings about degradation of ...		Epigenetic Reader Domain
T5343	UAMC-3203	UAMC 3203,UAMC3203	Ferroptosis
	UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).		Ferroptosis
T61268	Vutiglabridin	HSG4112	Phosphatase
	Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stabilit...		Phosphatase
T26412	A 274	A-274,A274
	A 274 is a highly aromatic, monosubstituted phenol antioxidant generated during differentiation of neuroblastoma cells.
T39899	Hu7691		Akt
	Hu7691 is an orally active, selective and potent Akt inhibitor that inhibits Akt1, Akt2 and Akt3, inhibits proliferation of neuroblastoma cells and induces differentiation of neuroblastoma cells.		Akt
T27655	JG-48
	JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.
T29030	U-101958 Maleate	U101958,U-101958,U 101958
	U-101958 Maleate is a ligand of dopamine D4 receptor. U-101958 Maleate also binds to a large sigma1 receptor-like component in SK-N-MC neuroblastoma cells and human cerebellum with high affinity.
T69346	A-357300
	A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM. Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models.
T70427	CB-64D
	CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.
T70284	Epolactaene
	Epolactaene is a neuritogenic compound in human neuroblastoma cells which selectively inhibit the activities of mammalian DNA polymerases and human DNA topoisomerase II.
T15412	GPP78	CAY10618	Autophagy
	GPP78 is a potent inhibitor of Nampt (IC50: 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion). GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells (IC50: 3.8 nM by inducing autophagy). GPP78 has anti-...		Autophagy
T10589	BPN-15606 besylate (1914989-49-3 free base)	BPN-15606 besylate	Others
	BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).		Others
T70151	MeTC7
	MeTC7 is a VDR antagonist, which can be synthesized from 7-dehydrocholesterol (6) in two steps, inhibits VDR selectively, suppresses the viability of cancer cell-lines, and reduces the growth of the spontaneous transgen...
T71026	MC2050 HCl
	MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide trea...
T68403	AZD-6918
	AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo. AZD6918 inhibited wild-type ...
T69149	L2-b
	L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggre...
T70224	Bupivacaine tartrate
	Bupivacaine is a BK/SK, Kv1, Kv3, TASK-2 K Channel and voltage-gated Na channel blocker used as an anesthetic. It maybe neurotoxic at high does, inducing apoptosis in neuroblastoma cells. It acts by binding to the intra...
T10589L	BPN-15606		Others
	BPN-15606, an orally active γ-secretase modulator (GSM), significantly reduces Aβ42 and Aβ40 production in SHSY5Y neuroblastoma cells, demonstrating IC50 values of 7 nM and 17 nM, respectively. This compound exhibits fav...		Others
T77101	Nivatrotamab
	Nivatrotamab (Hu3F8-BsAb), a humanized anti-GD2/CD3 bispecific antibody and T-cell engager specific to CD3 and GD2, is employed in the study of neuroblastoma [1].
T79905	Akt/ROCK-IN-1		ROCK
	Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 nM and 1.47 nM, respectively. It possesses antitumor efficacy against neuroblastoma [1].		ROCK
T38753	CR-1-31-B
	CR-1-31-B, a synthetic rocaglate, acts as a highly potent inhibitor of eIF4A. By disrupting the interaction between eIF4A and RNA, it effectively obstructs the initiation phase of protein synthesis. Specifically, CR-1-31...
T73234	USP7-IN-7
	USP7-IN-7, a potent USP7 inhibitor, exhibits an IC50 value of <10 nM. Demonstrating cytotoxicity against both p53-mutant and p53 wild-type blood cancer, as well as neuroblastoma cell lines at low nanomolar concentrations...
T78690	MAO-B-IN-18		Monoamine Oxidase
	MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A. It exhibits cytoprotective effects against hydrogen peroxide-induced damage in neuroblastoma and ...		Monoamine Oxidase

Compounds

NSC-87877

T16350

Synonym:

Target: Apoptosis, Phosphatase

UNC0379

T1841

Synonym:

Target: Histone Methyltransferase

NSC-87877 disodium

T6911

Synonym: NSC87877

Target: Apoptosis, Phosphatase

LY2365109 hydrochloride

Synonym: Tasmar,Ro 40-7592

Target: Apoptosis, Beta Amyloid, Transferase

Idebenone

T0412

Synonym: CV-2619

Target: Apoptosis, Antioxidant, Mitochondrial Metabolism

sulfopin

T9240

Synonym: Acetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(tetrahydro-1,1-dioxido-3-thienyl)-

Target: Apoptosis, c-Myc

AZD-3463

T1967

Synonym: ALK/IGF1R inhibitor

Target: Apoptosis, IGF-1R, ALK, Autophagy

NSC697923

T6611

Synonym: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran

Target: E1/E2/E3 Enzyme

Lorlatinib

T3061

Synonym: PF-6463922,PF-06463922,Loratinib

Target: Apoptosis, Tyrosine Kinases, ROS, ALK, ROS Kinase

Methyl 13-cis-4-Oxoretinoate

T3203

Synonym: 13-cis-4-Oxo-retinoic acid Methyl Ester,4-Keto 13-cis-Retinoic Acid Methyl Ester

Target: Others, Prostaglandin Receptor

Poly-D-lysine hydrobromide (MW 30000-70000)

T40363

Synonym: Poly-D-lysine HBr (MW 30000-70000)

Synonym: Naxitamab-gqgk,Humanized 3F8,Hu3F8

Target: DNA/RNA Synthesis

Target: Microtubule Associated, Autophagy

Tubulin polymerization-IN-47

T77651

Synonym:

Target: Microtubule Associated

JQAD1

T41180

Synonym:

Target: Epigenetic Reader Domain

UAMC-3203

T5343

Synonym: UAMC 3203,UAMC3203

Synonym: U101958,U-101958,U 101958

BPN-15606 besylate (1914989-49-3 free base)

T10589

Synonym: BPN-15606 besylate

Target: Monoamine Oxidase

Cat No.	Product Name	Synonyms	Targets
T1166	Ellipticine	NSC 71795,Elliptisine	Topoisomerase
	Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-6...		Topoisomerase
T3787	Didymin	Isosakuranetin-7-O-rutinoside,Neoponcirin	Apoptosis , Others
	Didymin (Neoponcirin) has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy. Didymin may be a potential therapeutic molecule fo...		Apoptosis , Others
T3S1589	Notoginsenoside Fa		Others
	1. Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.		Others
TN1933	Mitraphylline		IL Receptor , TNF , NF-κB
	Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils.		IL Receptor , TNF , NF-κB
T5229	DL -3,4-Dihydroxymandelic acid		Others
	3,4-Dihydroxymandelic acid is a minor metabolite of norepinephrine in humans. Patients with neuroblastoma experience elevated levels of 3,4-Dihydroxymandelic acid.		Others
T13354	Xanthoangelol		Apoptosis , Monoamine Transporter , Antibacterial , AMPK
	Xanthoangelol, which can be extracted from Angelica keiskei, inhibits obesity-induced inflammatory responses.Xanthoangelol has antimicrobial activity, inhibits monoamine oxidase, and induces apoptosis in neuroblastoma an...		Apoptosis , Monoamine Transporter , Antibacterial , AMPK
T3803	Specnuezhenide	Nuzhenide,Nuezhenide	Others , NF-κB , Wnt/beta-catenin
	Specnuezhenide (Nuezhenide) significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect t...		Others , NF-κB , Wnt/beta-catenin
T6718	Zingerone	Gingerone,Vanillylacetone,NSC 15335	NF-κB
	Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic and anti-tumor properties. Zingerone(Gi...		NF-κB
TN6062	1,3,9-Trimethyluric acid
	1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the ran...
T73640	Pancratistatin
	Pancratistatin, an isoquinoline alkaloid extracted from Hymenocallis littoralis, induces apoptosis in human melanoma cells and is utilized in researching neuroblastoma, leukemia, and breast cancer [1].
TN6685	Homovanillic Acid Sulfate
	Homovanillic acid sulfate is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.In psychiatry and neuroscience, brain and cerebrospinal fluid levels of homovanillic acid ar...
T36954	Nemorosone
	Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma ce...
TN3614	Cearoin		ERK , BCL , PARP , IκB/IKK , TNF , NF-κB , ROS , Caspase
	Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the expression of iNOS mRNA and LPS-induced mRNA expression of...		ERK , BCL , PARP , IκB/IKK , TNF , NF-κB , ROS , Caspase

Natural Products

Ellipticine

T1166

Synonym: NSC 71795,Elliptisine

Target: Topoisomerase

Didymin

T3787

Synonym: Isosakuranetin-7-O-rutinoside,Neoponcirin

Target: Apoptosis, Others

Target: IL Receptor, TNF, NF-κB

DL -3,4-Dihydroxymandelic acid

Target: Apoptosis, Monoamine Transporter, Antibacterial, AMPK

Specnuezhenide

T3803

Synonym: Nuzhenide,Nuezhenide

Target: Others, NF-κB, Wnt/beta-catenin

Zingerone

T6718

Synonym: Gingerone,Vanillylacetone,NSC 15335

Target: NF-κB

1,3,9-Trimethyluric acid

Homovanillic Acid Sulfate

Target: ERK, BCL, PARP, IκB/IKK, TNF, NF-κB, ROS, Caspase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01039	NBL1 Protein, Human, Recombinant (His)	Human	HEK293
	The Dan (Differential screening-selected gene aberrative in neuroblastoma, also known as N03) gene was first identified as the putative rat tumor suppressor gene and encodes a protein structurally related to Cerberus and...
TMPY-02670	NBL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The Dan (Differential screening-selected gene aberrative in neuroblastoma, also known as N03) gene was first identified as the putative rat tumor suppressor gene and encodes a protein structurally related to Cerberus and...
TMPY-00771	NBL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The Dan (Differential screening-selected gene aberrative in neuroblastoma, also known as N03) gene was first identified as the putative rat tumor suppressor gene and encodes a protein structurally related to Cerberus and...
TMPY-03487	NRAS Protein, Human, Recombinant (His)	Human	E. coli
	NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it ...
TMPY-01298	CADM1 Protein, Human, Recombinant (His)	Human	HEK293
	Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular...
TMPY-01011	FGFR1 Protein, Human, Recombinant (His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06036	FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06034	FGFR1 Protein, Human, Recombinant (beta (IIIb), His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPH-01775	N-myc Protein, Human, Recombinant (His)	Human	Yeast
	Positively regulates the transcription of MYCNOS in neuroblastoma cells.
TMPY-03410	TMEM25 Protein, Human, Recombinant (His)	Human	HEK293
	TMEM25 is a novel member of the immunoglobulin superfamily. Immunoglobulin superfamily members are implicated in immune responses, growth factor signaling, and cell adhesion. TMEM25 contains 1 Ig-like (immunoglobulin-lik...
TMPY-04499	CADM1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular...
TMPY-02945	Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEG...
TMPH-00001	CD133/PROM1 Protein-VLP, Human, Recombinant (His)	Human	HEK293
	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epit...
TMPH-02842	CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epit...
TMPH-01609	LGI1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regula...
TMPH-02458	PRNP Protein, Mesocricetus auratus, Recombinant (His & Myc)	Mesocricetus auratus	E. coli
	Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an ...
TMPY-00438	CNTN4 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Contactin-4, abbreviated as CNTN4, is a brain-derived protein belonging to the immunoglobulin superfamily. It has been found high expression in testes, thyroid, small intestine, uterus and brain. This protein is an neuro...
TMPY-02317	HDAC8 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Histone deacetylase 8, also known as HDAC8 and HDACL1, is a nucleus and cytoplasm protein that belongs to the histone deacetylase family and HD type 1 subfamily. Histone deacetylases (HDACs) are a growing family of enzym...
TMPY-01308	AGO1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Protein argonaute-1, also known as eukaryotic translation initiation factor 2C 1, EIF2C1, and AGO1, is a member of the argonaute family and ago subfamily. Protein argonaute-1 in humans is encoded by the EIF2C1 gene. Th...
TMPY-02593	CNTN4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Contactin-4, abbreviated as CNTN4, is a brain-derived protein belonging to the immunoglobulin superfamily. It has been found high expression in testes, thyroid, small intestine, uterus and brain. This protein is an neuro...
TMPY-01333	HDAC8 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Histone deacetylase 8, also known as HDAC8 and HDACL1, is a nucleus and cytoplasm protein that belongs to the histone deacetylase family and HD type 1 subfamily. Histone deacetylases (HDACs) are a growing family of enzym...
TMPY-01782	FGFR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06035	FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06033	FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-03926	FGFR1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-03350	FGFR1 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01781	FGFR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05777	FGFR1 Protein, Human, Recombinant (hFc)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-04371	FGFR1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05761	FGFR1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...

NBL1 Protein, Human, Recombinant (His)

TMPY-01039

Species: Human

Expression System: HEK293

NBL1 Protein, Mouse, Recombinant (His)

TMPY-02670

Species: Mouse

Expression System: HEK293

NBL1 Protein, Human, Recombinant (hFc)

TMPY-00771

Species: Human

Expression System: HEK293

NRAS Protein, Human, Recombinant (His)

TMPY-03487

Species: Human

Expression System: E. coli

CADM1 Protein, Human, Recombinant (His)

TMPY-01298

Species: Human

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (His)

TMPY-01011

Species: Human

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)

TMPY-06036

Species: Human

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (beta (IIIb), His)

TMPY-06034

Species: Human

Expression System: HEK293

N-myc Protein, Human, Recombinant (His)

TMPH-01775

Species: Human

Expression System: Yeast

TMEM25 Protein, Human, Recombinant (His)

TMPY-03410

Species: Human

Expression System: HEK293

CADM1 Protein, Mouse, Recombinant (His)

TMPY-04499

Species: Mouse

Expression System: HEK293

Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)

TMPY-02945

Species: Human

Expression System: Baculovirus-Insect Cells

CD133/PROM1 Protein-VLP, Human, Recombinant (His)

TMPH-00001

Species: Human

Expression System: HEK293

CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02842

Species: Mouse

Expression System: E. coli

LGI1 Protein, Human, Recombinant (His & Myc)

TMPH-01609

Species: Human

Expression System: E. coli

PRNP Protein, Mesocricetus auratus, Recombinant (His & Myc)

TMPH-02458

Species: Mesocricetus auratus

Expression System: E. coli

CNTN4 Protein, Mouse, Recombinant (His)

TMPY-00438

Species: Mouse

Expression System: Baculovirus-Insect Cells

HDAC8 Protein, Mouse, Recombinant (His)

TMPY-02317

Species: Mouse

Expression System: Baculovirus-Insect Cells

AGO1 Protein, Human, Recombinant (His)

TMPY-01308

Species: Human

Expression System: Baculovirus-Insect Cells

CNTN4 Protein, Human, Recombinant (His)

TMPY-02593

Species: Human

Expression System: Baculovirus-Insect Cells

HDAC8 Protein, Human, Recombinant (GST)

TMPY-01333

Species: Human

Expression System: Baculovirus-Insect Cells

FGFR1 Protein, Mouse, Recombinant (hFc)

TMPY-01782

Species: Mouse

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)

TMPY-06035

Species: Human

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)

TMPY-06033

Species: Human

Expression System: HEK293

FGFR1 Protein, Rhesus, Recombinant (His)

TMPY-03926

Species: Rhesus

Expression System: HEK293

FGFR1 Protein, Rhesus, Recombinant (hFc)

TMPY-03350

Species: Rhesus

Expression System: HEK293

FGFR1 Protein, Mouse, Recombinant (His)

TMPY-01781

Species: Mouse

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (hFc)

TMPY-05777

Species: Human

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (His & GST)

TMPY-04371

Species: Human

Expression System: Baculovirus-Insect Cells

FGFR1 Protein, Human, Recombinant (His), Biotinylated

TMPY-05761

Species: Human

Expression System: HEK293

Cat No.	Product Name
L8710	Cuproptosis Compound Library		411 compounds
	TargetMol’s Cuproptosis Compound Library is a collection of 411 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.

Libraries

Cuproptosis Compound Library

L8710

Compounds: 411