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(4)
By Target- COX
- NF-κB(4)
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- JNK(3)
- NOS(3)
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- Apoptosis(2)
- CSF-1R(2)
- Cholinesterase (ChE)(2)
- Others(14)
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Results for "
microglial
" in TargetMol Product Catalog- Inhibitors & Agonists50
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PLX5622
PLX-5622
T71001303420-67-8
PLX5622 is an orally active small-molecule CSF1R inhibitor that selectively depletes microglia in the brains of mice and rats. It is commonly used to establish models related to microglia-associated neuroinflammation, neurodegenerative diseases (such as Alzheimer's disease and Parkinson's disease), brain injury, and neuroimmune regulation.
- $97
Size
QTY
PLX5622 hemifumarate
T12505
PLX5622 hemifumarate is a highly selective, blood-brain barrier-permeable, and orally active CSF1R inhibitor with an IC50 of 0.016 μM and a Ki of 5.9 nM. It can be used to eliminate proliferating and specific microglia before and during disease progression and is applicable for inducing Alzheimer's disease models.
- $1,168
Size
QTY
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