methanesulfonate

Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).

Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures.

Colistin methanesulfonate sodium salt (Colistimethate Sodium) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.

Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.

2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate is a natural product that can be used as reference standards.

PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).

PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM, demonstrates slow reversibility and time-dependent inhibition. It operates in a noncompetitive manner relative to the acyl-CoA substrate, marking its efficacy in targeting DGAT2.

Tariquidar methanesulfonate hydrate (XR9576 methanesulfonate hydrate) is a selective and potent P-glycoprotein drug efflux pump inhibitor with potential anticancer activity that induces P-glycoprotein inhibition of the blood-brain barrier in rats.

BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), exhibiting 3.4- and 200-fold greater efficacy than trypsin, respectively.

NBI 35965 methanesulfonate  is a CRF1 antagonist.

TRPP3 channel inhibitor

Lifarizine methanesulfonate is a modulator of sodium-calcium channel that reduces ischemic brain damage.

Tetrabenazine methanesulfonate is a medicine formerly utilized as an antipsychotic and therapy for various movement disorders. Tetrabenazine methanesulfonate blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high-affin

Aniline, p-(5-phenylpentyloxy)-, methanesulfonate is a bioactive chemical.

m-Anisidine, 4-((5-(benzyloxy)pentyl)oxy)-, methanesulfonate is a bioactive chemical.

m-Anisidine, 4-(4-phenylbutoxy)-, methanesulfonate is a bioactive chemical.

Methanesulfonic acid, compd. with 4-(octyloxy)-m-toluidine (7CI) is a bioactive chemical.

m-Toluidine, 4-(octyloxy)-alpha-(phenylthio)-, methanesulfonate is a bioactive chemical.

Phthalimide, N-(2-(p-aminophenoxy)ethyl)-, methanesulfonate is a bioactive chemical.

Phthalimide, N-(3-(p-aminophenoxy)propyl)-, methanesulfonate is a bioactive chemical.

Quinacrine methanesulfonate is a bioactive chemical.

CYH33 methanesulfonate is a highly selective and orally active inhibitor of PI3Kα, with IC50 values of 5.9 nM, 598 nM, 78.7 nM, and 225 nM against the α, β, δ, and γ isoforms, respectively. This compound effectively inhibits the phosphorylation of Akt and ERK, leading to a significant G1 phase arrest in breast cancer cells and non-small cell lung cancer (NSCLC) cells. Additionally, CYH33 methanesulfonate demonstrates potent activity against solid tumors.

Ethyl methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T65157 and the CAS number is 62-50-0.

Phenyl methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T65303 and the CAS number is 16156-59-5.