il 24

Expression system: HEK293 Cells
Length: 24-355, Partial
Activity: ELISA、SPR

IL-24 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 44.6 kDa and the accession number is A0A7R8C2Y5.

Expression system: HEK293 Cells
Length: 24-353, Partial
Activity: BLI、ELISA

IL-24 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.5 kDa and the accession number is A0A7R8C2Y5.

Expression system: HEK293 Cells
Length: 29-161, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 29-161, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 31-163, Full Length of Mature Protein
Activity: ELISA

The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease.

IL-12A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P29459.

Expression system: HEK293 Cells
Length: 24-374, Partial
Activity: SPR

Expression system: E. coli
Length: 24-153, Partial
Activity: ELISA

Expression system: E. coli
Length: 24-164, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 24-221, Partial
Activity: ELISA、SPR

Expression system: HEK293 Cells
Length: 24-164, Full Length of Mature Protein
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 24-155 (mutation), Full Length of Mature Protein
Activity: Cell Activity

Expression system: Baculovirus Insect Cells
Length: 24-153, Partial
Activity: ELISA

Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins and virally encoded IL-18BP homologs. It augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. In the presence of IL-12 or IL-15, IL-18 enhances anti-viral Th1 immune responses by inducing IFN-gamma production and the cytolytic activity of CD8+ T cells and NK cells. In the absence of IL-12 or IL-15, however, IL-18 promotes production of the Th2 cytokines IL-4 and IL-13 by CD4+ T cells and basophils.

Expression system: HEK293 Cells
Length: 24-155, Full Length of Mature Protein
Activity: ELISA、SPR

Expression system: HEK293 Cells
Length: 48-454, Extracellular Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 24-540, Extracellular Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 24-155, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 19-197, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 24-372, Partial
Activity: Not Tested