ibd

Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.

1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases.

Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmental changes.

Kibdelin D exhibits resistance against Gram-positive bacteria, showing effectiveness comparable to Vancomycin against Staphylococcus aureus (including methicillin-resistant strains).

Kibdelin A is effective against Gram-positive bacteria and exhibits effects similar to Vancomycin against Staphylococcus aureus (including methicillin-resistant strains).

Kibdelin C1 exhibits resistance against Gram-positive bacteria and demonstrates similar effectiveness to Vancomycin in combatting Staphylococcus aureus, including methicillin-resistant strains (MRSA).

Kibdelin B exhibits resistance against Gram-positive bacteria and demonstrates effects similar to Vancomycin, particularly against Staphylococcus aureus, including methicillin-resistant strains.

Kibdelone A, a natural heterocyclic polyketide, was first isolated from the soil actinomycete Kibdelosporangium. It exhibits potent and selective cytotoxicity against various human tumor cell lines, in addition to showing significant antibacterial and nematocidal activity.

Kibdelin C2 exhibits resistance against Gram-positive bacteria and demonstrates efficacy against Staphylococcus aureus (including methicillin-resistant strains) comparable to that of Vancomycin.

L-Homocysteine is a biological thiol involved in various diseases and pathological conditions. It is a marker for atherosclerosis and can exacerbate intestinal inflammation in inflammatory bowel disease (IBD) by promoting the expression of 5-LOX and COX-2, making it suitable for inducing vascular endothelial inflammation models.