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Results for "

hypolipidemic

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    46
    TargetMol | Inhibitors_Agonists
  • Natural Products
    20
    TargetMol | Natural_Products
  • Recombinant Protein
    2
    TargetMol | Recombinant_Protein
Hepronicate
Megrin
T154717237-81-2In house
Hepronicate(Megrin) is a small molecule compound with hypolipidemic and vasodilatory activity.
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6-8 weeks
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Imanixil
HOE-402 free base
T1556175689-93-9In house
Imanixil (HOE-402 free base) is an LDL receptor (LDLR) inducer, a hypolipidemic and hypocholesterolemic compound with antiatherogenic activity that inhibits the production of very low-density lipoproteins (VLDLs).Imanixil acts by stimulating the LDL receptor pathway.
  • Inquiry Price
6-8 weeks
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Lifibrol
U 83860, K-12148, K-12.148, U-83860, K12148
T2783296609-16-4In house
Lifibrol (U-83860) is an inhibitor of cholesterol synthesis.Lifibrol has anticholesterol and hypolipidemic properties and promotes the conversion of LDL Apo B-100 in patients with hypercholesterolemia and mixed hyperlipidemia.
  • Inquiry Price
6-8weeks
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TargetMol | Inhibitor Sale
BMS-212122
UNII-0Z473OO6GB, BMS212122, BMS 212122
T30506194213-64-4In house
BMS-212122 (UNII-0Z473OO6GB) is a potent inhibitor of microsomal triglyceride transfer protein (MTP) and has shown hypolipidemic effects in animal studies.BMS-212122 significantly reduced lipid content and monocyte-derived (CD68+) cells in atherosclerotic plaques.
  • Inquiry Price
8-10weeks
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Berberine ursodeoxycholate
HTD1801, BUDCA
T679741868138-66-2In house
Berberine ursodeoxycholate (HTD1801) is an orally effective hypolipidemic agent, an ionic salt of Berberine and Ursodeoxycholic acid.Berberine ursodeoxycholate has a wide range of metabolic activity and significantly reduces liver fat content. Berberine ursodeoxycholate has been used in studies of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.
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Simvastatin
MK-0733, MK 733
T068779902-63-9
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovascular disease.
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Acipimox
Olbemox, K-9321
T116251037-30-0
Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.
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TargetMol | Inhibitor Sale
Gemfibrozil
CI-719, Jezil, Decrelip, Lopid
T141525812-30-0
Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfibrozil is a fibric acid derivative with hypolipidemic effects. This enhances triglyceride-rich lipoprotein clearance and reduces the expression of apolipoprotein C-III (apoC-III). The reduction in hepatic production of apoC-III result in the subsequent reduction of serum levels of very-low-density-lipoprotein cholesterol (VLDL-C). In addition, gemfibrozil-mediated PPARalpha stimulation of apoA-I and apoA-II expression results in an increase in high-density lipoprotein cholesterol (HDL-C).
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Xenalipin
BW 207U
T1986484392-17-6
Xenalipin (BW 207U) has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.
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TargetMol | Inhibitor Sale
Phloracetophenone
2,4,6-trihydroxyacetophenone, 1-(2,4,6-Trihydroxyphenyl)ethanone
T2840480-66-0
Phloracetophenone (1-(2,4,6-Trihydroxyphenyl)ethanone) has antiobesity and hypolipidemic effects, may be partly mediated by delaying the intestinal absorption of dietary fat by inhibiting pancreatic lipase activity.
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Squalene
Super Squalene, AddaVax
T4749111-02-4
Squalene (AddaVax) is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran, wheat germ, and olives. All higher organisms produce squalene, including humans. Squalene is an intermediate product in the synthesis of cholesterol and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity.
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berberine
Umbellatine, Berberin
T4S07972086-83-1
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV AIDS. 3. Berberine seems to act as an herbal antidepressant and a neuroprotector against neurodegenerative disorders. 4. Berberine is used in histology for staining heparin in mast cells. As a natural dye, berberine has a colour index of 7516. 5. Berberine reduces hepatic fat content in rats with nonalcoholic fatty liver disease; also prevents proliferation of hepatic stellate cells (HSCs), which are central for the development of fibrosis during liver injury. 6. Berberine can ameliorate proinflammatory cytokines-induced intestinal epithelial tight junction damage in vitro, and berberine may be one of the targeted therapeutic agents that can restore barrier function in intestinal disease states. 7. Berberine has antineoplastic effects, including breast cancer, leukemia, melanoma, epidermoid carcinoma, hepatoma, pancreatic cancer, oral carcinoma, tongue carcinoma, glioblastoma, prostate carcinoma and gastric carcinoma, etc.
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Crocin (Gardenia Fruits Extract)
T5311
Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.). Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidemic effects.
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Rosuvastatin
ZD 4522
T1676287714-41-4
Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR) (IC50=11 nM), selective and competitive. Rosuvastatin has hypolipidemic and antiatherosclerotic effects.
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Epiandrosterone
trans-Androsterone, iso-Androsterone, EpiA, 3β-Androsterone
T2195481-29-8
Epiandrosterone (EpiA) is a dehydroepiandrosterone metabolite and a precursor of testosterone and estradiol with hypolipidemic and anabolic property.
    Inquiry
    Neoandrographolide
    Neoandrographiside
    T388427215-14-1
    Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iNOS and COX-2 expression through inhibiting p38 MAPKs activation.Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP)-overexpressing Jurkat cells, a model for chemoresistance.
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    Pirozadil
    T512354110-25-7
    Pirozadil shows hypolipidemic activity.
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    TargetMol | Inhibitor Sale
    Enniatin complex
    T1120211113-62-5
    Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it has demonstrated the ability to induce apoptosis in multiple cancer cell lines. In addition to these activities, the Enniatin complex possesses ionophoric, antibiotic, and in vitro hypolipidemic properties.
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    Pirinixil
    BR-931
    T1382165089-17-0
    Pirinixil is a hypolipidemic low toxicity agent.
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    6-8 weeks
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    TA-1801
    T1390988352-44-7
    TA-1801 is an agent of hypolipidemic.
    • Inquiry Price
    6-8 weeks
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    Y-9738
    T1397259399-41-6
    Y-9738 is an agent of hypolipidemic.
    • Inquiry Price
    6-8 weeks
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    Cetaben
    T1493355986-43-1
    Cetaben, a PPARα-independent peroxisome proliferator, is a non-fibrotic lipid-lowering drug that effectively reduces cholesterol and triglyceride concentrations.
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    Etofylline clofibrate
    T1525654504-70-0
    Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.
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    7-10 days
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    Biclofibrate HCl
    Biclofibrate hydrochloride, 35X9O753CT
    T20269335556-22-0
    Biclofibrate is a hypolipidemic compound that has been investigated for its potential to lower blood lipid levels.
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