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Results for "

fluorinated

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    36
    TargetMol | Inhibitors_Agonists
  • Dye Reagents
    1
    TargetMol | Dye_Reagents
  • Natural Products
    1
    TargetMol | Natural_Products
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    2
    TargetMol | Inhibitors_Agonists
Fludarabine
NSC 118218, Fludarabinum, F-ara-A
T103821679-14-1
Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and lymphoma.
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6-fluorinated-aristeromycin2c
T677842236598-84-6In house
6-fluorinated inated-aristeromycin2c showed antiviral activity against heat virus, Zika virus and Sars coronavirus.
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6-8 weeks
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Difluorinated H2S Fluorescent Probe 1
T377202103919-91-9
Difluorinated H2S probe 1 is a fluorescent probe for hydrogen sulfide (H2S).1It selectively fluoresces in the presence of H2S over Zn2+, Fe3+, S2O32-, ClO-, SO32-, H2O2, NO2-, cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) when used at a concentration of 1 μM. Difluorinated H2S probe 1 displays excitation/emission maxima of 365/450 nm, respectively. 1.Zhang, J., Gao, Y., Kang, X., et al.o,o-Difluorination of aromatic azide yields a fast-response fluorescent probe for H2S detection and for improved bioorthogonal reactionsOrg. Biomol. Chem.15(19)4212-4217(2017)
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Perfluorinated SAHA
T710111308677-14-6
Perfluorinated SAHA is an HDAC inhibitor for use in cancer treatment regimens, with demonstrated greater antiproliferative properties than SAHA . PFSAHA has also been shown to have higher selectivity for PA3774, an HDAC-like enzyme from P. aeruginosa, as well as other HDACs, which may prove beneficial for developing novel chemotherapeutic treatments for cancer.
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6-8 weeks
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Flurocitabine HCl
Flurocitabine HCl(37717-21-8 Free base)
T27342L40505-45-1In house
Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).Flurocitabine HCl has demonstrated antitumor activity in phase I studies in acute leukemia and solid tumors.
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Piflufolastat
DCFPYL
T312241423758-00-2In house
Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat can be used to prepare piflufolastat F 18 (DCFPyL F-18).
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8-10weeks
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SR4554
SR 4554
T34705167648-73-9In house
SR4554 is a fluorinated 2-nitroimidazole non-invasive tumor hypoxia probe for the detection of tumor hypoxia as detected by 19F magnetic resonance spectroscopy (MRS).
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6-8 weeks
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Florfenicol
Nuflor, Aquafen
T045476639-94-6
Florfenicol (Aquafen) is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, and Haemophilus somnus, to treat bovine interdigital phlegmon associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.
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Florfenicol
SCH-25298, (-)-Florfenicol
T0454L73231-34-2
Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnus, and Pasteurella multocida, for therapy of bovine interdigital phlegmon (foot rot, infectious pododermatitis, acute interdigital necrobacillosis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. This compound is also used in aquaculture and is approved for use in the United States for the therapy of enteric septicemia in catfish.
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Flucytosine
Ro 2-9915, NSC 103805, Fluorocytosine, 5-Fluorocytosine
T09862022-85-7
Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.
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Trifluridine
Viroptic, Trifluridina, Trifluorothymidine, NSC 75520, NSC 529182, 5-Trifluorothymidine
T142870-00-8
Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.
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Fluticasone furoate
Veramyst, Allermist, Avamys, Fluticasone furoate
T21404397864-44-7
Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure. Fluticasone furoate can be used as a nasal spray for studies about allergic rhinitis treatment.
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4-6 weeks
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Fludarabine Phosphate
NSC 312887 Phosphate, fludara Phosphate, F-ara-A (NSC 312887) Phosphate, F-ara-AMP
T650175607-67-9
Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase alpha, ribonucleotide reductase, and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.
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ONC212
T73981807861-48-8
ONC212 [a fluorinated-ONC201 analogue] is a selective GPR132 agonist.
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Hydrazinium hydroxide
T86981805818-57-8
Hydrazinium hydroxide is a fluorinated carboxylic acid that has been used to study the mechanisms of action of enzymes, hormones and other biomolecules. It has also been used to study the effects of various drugs on the body and to study the effects of environmental toxins on the body.
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Fludrocortisone acetate
9α-Fluorcortisol acetate, 9α-Fludrocortisone acetate, 9α-fluorocortisol acetate
T1666514-36-3
Fludrocortisone acetate (9α-Fludrocortisone acetate), a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and initiates transcription of glucocorticoid-responsive genes like lipocortins to inhibit phospholipase A2 (PLA2). As the acetate salt of a synthetic fluorinated corticosteroid, it exhibits anti-inflammatory and antiallergic activities. PLA2 inhibition prevents arachidonic acid release, a precursor of eicosanoids such as prostaglandins and leukotrienes, which are key mediators in the pro-inflammatory response. As a mineralocorticoid-receptor agonist, it stimulates Na+ reabsorption, water retention, and K+ and H+ secretion in the distal tubules and collecting ducts of the kidney.
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Loratadine specified impurity F
11-Fluoro dihydroloratadine
T20814125743-80-8
Loratadine specified impurity F is a fluorinated analog of Loratadine.
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Decafluorobenzophenone
Perfluorobenzophenone
T21079853-39-4
Decafluorobenzophenone is used in the synthesis of fluorinated acridones and acridines. Decafluorobenzophenone alcoholic solution generates radical anion and ketyl which can be studied by electron spin resonance spectra. It undergoes photolysis to form ke
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6-8 weeks
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Flopristin
RPR-132552,RPR-132552A,RPR 132552,RPR 132552A
T25424318498-76-9
Flopristin, a semi-synthetic antibiotic of the streptogramin A class, is a fluorinated derivative of pristinamycin IIB.
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Nemonoxacin Malate
TG-873870,TG873870,TG 873870
T28154951163-60-3
Nemonoxacin is a non-fluorinated quinolone antibiotic.
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7-10 days
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Perfluidone
SB1528,SB 1528,Destun,SB-1528,WL 43423
T3393037924-13-3
Perfluidone is a a fluorinated arylalkylsulphonamide plant growth regulator and herbicide.
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VM4-037 F-18
(F18)Vm-4-037,VM4037 F-18,VM4 037 F-18
T350671071471-25-4
VM4-037 F-18 is a fluorinated PET imaging agent used for carbonic anhydrase IX.
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Vinflunine ditartrate
T37037194468-36-5
Vinflunine ditartrate, a fluorinated microtubule inhibitor and member of the Vinca alkaloids family, exhibits anti-angiogenic, vascular-disrupting, and anti-metastatic properties. It presents a potential avenue for studying transitional cell carcinoma of the urothelial tract, non-small cell lung cancer, and breast carcinoma[1][2].
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MJ33 lithium salt
T384041007476-63-2
MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, a fluorinated phospholipid analog that inhibits the phospholipase A2 (PLA2) activity of peroxiredoxin 6 (Prdx6), and is used in the study of acute lung injury.
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7-10 days
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