cortisone

Cortisone (17-Hydroxy-11-dehydrocorticosterone) is a corticosteroid with potent glucocorticoid activity.

Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.

Cortisone-d8 is a deuterated compound of Cortisone.

Cortisone (Standard) is the standard substance of Cortisone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cortisone (17-Hydroxy-11-dehydrocorticosterone) is a corticosteroid with potent glucocorticoid activity.

Cortisone acetate (Standard) is the standard substance of Cortisone acetate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.

21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.

Fludrocortisone (Florinef) is a synthetic corticosteroid with moderate glucocorticoid potency and greater mineralocorticoid potency. Fludrocortisone is in research use for the treatment of hypotension.[3]

Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.

Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.

Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilization, and renal calcium excretion, as well as suppressing immune and inflammatory responses.

Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.

Tetrahydrocortisone, the inactive metabolite of cortisone, is a product of cortisone's involvement in the stress response and its enzymatic reduction, and can be used as an indicator of cortisol metabolism.

5β-Dihydrocortisone, a sterol metabolite derived from cortisone, is produced in the liver through the action of 5β-reductase (AKR1D1).

CORTISONE(2,2,4,6,6,9,12,12-d8) is a deuterated compound of CORTISONE. CORTISONE has a CAS number of 53-06-5. Cortisone is a corticosteroid with potent glucocorticoid activity.

5β-Dihydrocortisone is a sterol metabolite of cortisone produced by 5β-reductase (AKR1D1) in the liver, existing as a mixture of isomers.

Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.

Hydrocortisone Valerate (Westcort) has anti-inflammatory, antipruritic and vasoconstrictive properties.

Hydrocortisone buteprate is a medium-potent, non-halogenated double-ester derivative of hydrocortisone that has researches indicate highly favorable benefit-to-risk ratio in inflammatory dermatological disorders.

Fludrocortisone acetate (9α-Fludrocortisone acetate), a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and initiates transcription of glucocorticoid-responsive genes like lipocortins to inhibit phospholipase A2 (PLA2). As the acetate salt of a synthetic fluorinated corticosteroid, it exhibits anti-inflammatory and antiallergic activities. PLA2 inhibition prevents arachidonic acid release, a precursor of eicosanoids such as prostaglandins and leukotrienes, which are key mediators in the pro-inflammatory response. As a mineralocorticoid-receptor agonist, it stimulates Na+ reabsorption, water retention, and K+ and H+ secretion in the distal tubules and collecting ducts of the kidney.

Hydrocortisone cypionate is a corticosteroid ester and synthetic glucocorticoid corticosteroid.

Hydrocortisone-21-lysinate is a hydrocortisone prodrug that is water soluble.

Acyclovir mixture with hydrocortisone is used for Herpes simplex labialis.

Benzodrocortisone is a corticosteroid.

Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid cream used to treat various skin diseases.