cancer drug discovery

A unique collection of 3660 drugs with anti-cancer activity or potential anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);

A unique collection of 573 cancer cell differentiation inducing compounds for high throughput and high content screening;

A unique collection of 2440 compounds with anti-breast cancer therapeutic activity or targeting breast cancer's major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study;

A unique collection of 2508 pancreatic cancer related compounds can be used in HTS and HCS;

1880 compounds associated with colorectal cancer that can be used for high-throughput and high-content screening.

2256 compounds associated with prostate cancer that can be used for high-throughput and high-content screening.

A unique collection of 900 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;

A unique collection of 3000 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;

A unique collection of 325 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.

A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS);

A unique collection of 523 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening;

A unique collection of 1470 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;

A unique collection of 500 natural alkaloids can be used for high throughput and high content screening;

A unique collection of 3128 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism;

A unique collection of 1650 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc.

A unique collection of 1150 cytoskeleton-related compounds, can be used for HTS and HCS;

A unique collection of 861 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;

A unique collection of 755 nuclear receptor signaling targeted compounds for high throughput and high content screening;

A unique collection of 1920 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);

A unique collection of 2240 compounds with anti-lung cancer therapeutic activity or targeting lung cancer's major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study;

A unique collection of 941 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and cancer;

Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. In humans, oxidative stress is thought to be involved in the development of atherosclerosis, heart failure, myocardial infarction, cancer, infection etc. Antioxidants are a class of compounds that counteract oxidative stress and reduce oxidative damage. The TargetMol Antioxidant Compound Library is a unique collection of 2010 small molecules with inhibitory effects on oxidative stress and is a useful tool for high-throughput screening and high-content screening in the study of oxidative stress.

A unique collection of 700 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);

128 methylation-related compounds that can be used for high-throughput and high-content screening.