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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4966 | Ufenamate | Flufenamic acid butyl ester,Butyl flufenamate | Others |
Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for skin diseases | |||
T2690 | Tranilast | MK 341,SB 252218 | RAAS , Prostaglandin Receptor |
Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders. | |||
T2648 | Pimecrolimus | SDZ-ASM 981,ASM 981 | Others |
Pimecrolimus (SDZ-ASM 981), a calcineurin inhibitor immunosuppressant, binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction cascade mediated by calcineuri... | |||
T75113 | GLPG2534 | GLPG-2534 | IRAK |
GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 inhibits human and mouse IRAK4 and could be used to study psoriasis and atopic dermatitis. | |||
T14981 | Clobetasone butyrate | Glucocorticoid Receptor | |
Clobetasone butyrate, a synthetic glucocorticoid with topical anti-inflammatory activity, is effective in treating corticosteroid-responsive dermatoses, such as atopic dermatitis and psoriasis, especially within skin tis... | |||
T6S0232 | Eriodictyol | Huazhongilexone | Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite |
1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3.... | |||
T76704 | Tralokinumab | CAT-354,LP 0162 | IL Receptor |
Tralokinumab is a fully human IgG4 monoclonal antibody with a high affinity for IL-13 alone. Tralokinumab's potential anti-inflammatory activity prevents IL-13 receptor interaction and subsequent downstream signaling and... | |||
T76884 | Spesolimab | BI 655130 | IL Receptor |
Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. IL-36 plays an important role in the immune system and is associated with a reduction in biomarkers associated with congenital Th1/Th17 and neutrophil p... | |||
T67202 | Benvitimod | ||
Benvitimod is a non-steroidal anti-inflammatory drug (NSAID) potentially for the treatment of atopic dermatitis. | |||
T78333 | Rocatinlimab | AMG 451,KHK4083 | |
Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated IgG1 anti-OX40 monoclonal antibody indicated for atopic dermatitis (AD) research [1]. | |||
T76816 | Lokivetmab | ||
Lokivetmab, an Anti-Canine IL31 Recombinant Antibody, is a monoclonal antibody targeting canine IL-31, utilized in research related to atopic dermatitis (AD) in dogs [1]. | |||
T78299 | Amlitelimab | KY1005,SAR445229 | |
Alvircept sudotox, an anti-OX40 Ligand (OX40L) monoclonal antibody (mAb), disrupts the OX40-OX40L interaction and is used in atopic dermatitis research [1] [2] [3]. | |||
T78207 | Lepzacitinib | JAK | |
Lepzacitinib, a Janus kinase inhibitor, specifically targets JAK 1/3. It demonstrates an anti-inflammatory effect and efficacy in inhibiting atopic dermatitis as well as other skin diseases [1]. | |||
T60521 | Doxepin | ||
As a tricyclic antidepressant, Doxepin inhibits the reuptake of serotonin and norepinephrine. Doxepin shows therapeutic effects on atopic dermatitis and chronic urticaria that also improves cognitive processes as well as... |