msc — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T33514	MSC 2032964A	MSC-2032964A,MSC2032964A	ASK
	MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 i...		ASK
T60148	MSC-4106		YAP
	MSC-4106, an orally active and potent YAP/TAZ-TEAD inhibitor, disrupts TEAD1 and TEAD3 auto-palmitoylation and demonstrates significant efficacy in the NCI-H226 tumor xenograft model [1].		YAP
T7727	Se-Methylselenocysteine	Se MSC,SeMCys,MSeC,Se-MSC,SeMSC	BCL , IAP , Caspase
	Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.		BCL , IAP , Caspase
T73378	MSC-1186
	MSC-1186 is a potent and highly selective inhibitor targeting the pan-SRPK family, including SRPK1, SRPK2, and SRPK3, with IC 50 values of 2.7 nM, 81 nM, and 0.6 nM, respectively. Its specificity and effectiveness make i...
T12115	MSC2360844		PI3K
	MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).		PI3K
TQ0266	MSC2530818		CDK
	MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).		CDK
T6121	Tepotinib	EMD-1214063,MSC2156119	Trk receptor , c-Met/HGFR , TAM Receptor
	Tepotinib (EMD-1214063) is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.		Trk receptor , c-Met/HGFR , TAM Receptor
T60098	MSC2504877	3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one	Others
	MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phos...		Others
T2771	Orcinol glucoside	Sakakin	Antioxidant
	Orcinol glucoside (Sakakin) (OG), an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn, shows potent antioxidative and anxiolytic activities without sedative effects.		Antioxidant
T12114	MSC1094308		p97
	MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.		p97
T71161	Thiorphan disulfide
	Thiorphan disulfide is an impurity of Racecadotril -- an antidiarrheal and enkephalinase inhibitor that reduces the amount of water and electrolytes absorbed into the intestine.
T39094	MSC2360844 hemifumarate
	MSC2360844 hemifumarate is a highly potent and orally active compound that acts as a selective inhibitor of PI3Kδ, with an IC50 value of 145 nM. This compound exhibits exceptional selectivity against a comprehensive pane...
T9238	KI-7		Adenosine Receptor
	KI-7 is an adenosine A2B receptor positive allosteric modulator.		Adenosine Receptor
T71383	NB-533
	NB-533 is a macrocyclic peptidic BACE-1 inhibitor.
T29899	Alpha-MSCS	alpha-Methylserotonin creatinine sulfate,alpha Methylserotonin creatinine sulfate,alphaMSCS
	α-MSCs (α-methylserotonin creatinine sulfate) are neurotransmitters.
T4387	Evobrutinib	MSC2364447C,M2951	BTK
	Evobrutinib(M2951) , also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton's tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B...		BTK
TL0008	Gigantol		Wnt/beta-catenin , Glucosidase
	Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...		Wnt/beta-catenin , Glucosidase
TP1300	GsMTx4 TFA (1209500-46-8 free base)	GsMTx4 TFA	Piezo Channel
	GsMTx4 TFA (1209500-46-8 free base) (GsMTx4 TFA) is a spider venom peptide that selectively inhibits cationic permeable mechanically-sensitive channels (MSCs) belonging to the Piezo and TRP channel families.		Piezo Channel
T16947	SU16f	3-substituted indolin-2-one 16f,SU-16F,SU 16F	PDGFR
	SU16f (3-substituted indolin-2-one 16f) is a potent and selective PDGFRβ inhibitor (IC50s: 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively). Neutralization of PDGFRβ receptor by SU16f blocks the promoting...		PDGFR
TP1152	Fibronectin Adhesion-promoting Peptide TFA	Heparin Binding Peptide TFA
	Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal...