mers-cov — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9614	MERS-CoV-IN-1		SARS-CoV
	MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS).		SARS-CoV
T7766	Remdesivir	GS-5734	SARS-CoV , DNA/RNA Synthesis
	Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of viruses. Remdesivir is active against Ebola, SARS, and MERS viru...		SARS-CoV , DNA/RNA Synthesis
T72231	SARS-CoV-2/MERS Mpro-IN-2
	SARS-CoV-2/MERS Mpro-IN-2 is a potent inhibitor of the main proteases of SARS-CoV-2 and MERS, demonstrating IC50 values of 0.21 and 0.07 µM, respectively.
T72230	SARS-CoV-2/MERS Mpro-IN-1
	SARS-CoV-2/MERS Mpro-IN-1 is a potent inhibitor of the main proteases in SARS-CoV-2 and MERS, exhibiting IC50 values of 0.10 and 0.06 µM, respectively.
T60085	MM3122	GTPL11533,MM-3122,Ac-GQFR-kbt	SARS-CoV
	MM3122 (MM-3122) is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells.		SARS-CoV
T8498	EIDD-1931	Beta-d-N4-hydroxycytidine	Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
	EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndr...		Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
T60951	Molnupiravir	EIDD-2801,Lagevrio,MK-4482	SARS-CoV , Influenza Virus
	Molnupiravir (MK-4482) (EIDD-2801) is a prodrug of the ribonucleoside analog EIDD-1931 which is orally bioavailable. Molnupiravir can be used in COVID-19, seasonal and pandemic influenza research that has broad spectrum ...		SARS-CoV , Influenza Virus
T3374	Dihydrotanshinone I	DHTS,15,16-dihydrotanshinone I	SARS-CoV , ROS
	Dihydrotanshinone I (DHTS) is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of cardiovascular diseases.		SARS-CoV , ROS
T6573	E 64c	NSC 694279,EP 475,Loxistatin Acid	SARS-CoV , Cysteine Protease
	E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.		SARS-CoV , Cysteine Protease
T36652	Anti-MERS-3A1 mAb	Anti-MERS-3A1 mAb
	Anti-MERS-3A1 mAb (MERS-3A1) is a high-affinity human monoclonal IgG1 antibody derived from CHO cells. It effectively inhibits the interaction between the MERS-CoV spike protein and the DPP4 receptor[1].
T12836	SARS-CoV-2-IN-1		Others
	SARS-CoV-2-IN-1 is a potent inhibitor of Mpro(SARS-CoV-2 Mpro, SARS-CoV Mpro and MERS-CoV Mpro with IC50s of 0.67, 0.90 and 0.58 μM, respectively).		Others
T68674	Vincapusine
	Vincapusine is a natural inhibitor of 3C-like protease (3CLpro), targeting SARS-CoV-2 3CLpro, SARS-CoV 3CLpro and MERS-CoV 3CLpro.
T78867	WU-04		SARS-CoV
	WU-04 is a non-covalent inhibitor targeting the 3CLpro protein of SARS-CoV-2, demonstrating high inhibitory effects on 3CLpro from six SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda, and Omicron) as well as two o...		SARS-CoV
T72313	SARS-CoV-2 3CLpro-IN-11
	SARS-CoV-2 3CLpro-IN-11(11d) is a broad-spectrum antiviral compound that effectively inhibits the SARS-CoV-2 3CL protease, achieving an IC50 of 140 nM. Additionally, it exhibits inhibitory activity against SARS-CoV-1 and...
T39334	Remdesivir nucleoside monophosphate
	Remdesivir nucleoside monophosphate, a metabolite of Remdesivir, is a potent antiviral compound with nucleoside analogue characteristics. It exhibits effective antiviral activity against both SARS-CoV and MERS-CoV.
T76669	Anti-MERS-D12 mAb
	Anti-MERS-D12 mAb (MERS-D12; MERS Antibody-D12), a human monoclonal IgG1, specifically targets the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD). By directly binding to this region, it effec...
T69547	UAWJ9-36-3
	UAWJ9-36-3 is a SARS-CoV-2 Protease inhibitor (IC50 = 54 nM). UAWJ9-36-3 showed potent binding and enzymatic inhibition against the Mpro's from SARS-CoV-2, SARS-CoV, MERS-CoV, HCoV-OC43, HCoV-NL63, HCoV-229E, and HCoV-HK...
T69548	UAWJ9-36-1
	UAWJ9-36-1 is a SARS-CoV-2 Protease inhibitor (IC50 = 51 nM). UAWJ9-36-1 showed potent binding and enzymatic inhibition against the Mpro's from SARS-CoV-2, SARS-CoV, MERS-CoV, HCoV-OC43, HCoV-NL63, HCoV-229E, and HCoV-HK...
T72312	SARS-CoV-2 3CLpro-IN-10
	SARS-CoV-2 3CLpro-IN-10(5d) is a potent inhibitor of the SARS-CoV-2 3CL protease, exhibiting an IC50 value of 190 nM, and demonstrates varied efficiency against other coronaviruses with IC50 values of 790 nM for SARS-CoV...
T79339	NSC89641		SARS-CoV
	NSC89641 demonstrates potent inhibition of MERS-CoV M^pro, achieving an IC_50 value of less than 3.5 µM. Furthermore, it exerts significant inhibitory effects on SARS-CoV-2 M^pro enzymatic activity, with an IC_50 of 3.05...		SARS-CoV