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Conjugation and labelingClick chemistry
Click chemistry dyes are a class of fluorescent probes modified with bioorthogonal reaction groups, including Azide/N3, DBCO, Tetrazine, TCO, Norbornene, and others. They can efficiently, specifically, and with minimal interference form covalent bonds with biomolecules carrying complementary groups under physiological conditions.Click chemistry dyes are a class of fluorescent probes modified with bioorthogonal reaction groups, including Azide/N3, DBCO, Tetrazine, TCO, Norbornene, and others. They can efficiently, specifically, and with minimal interference form covalent bonds with biomolecules carrying complementary groups under physiological conditions.
5-TAMRA Azide
TAMRA Azide, isomer 5
T678401006592-61-5
5-TAMRA Azide (TAMRA Azide, isomer 5) is the orange-fluorescent probe that is compatible with various excitation sources including mercury arc, tungsten and xenon arc lamps, the 544 nm line of the Helium-Neon laser and the 532 nm green laser line. It is predominantly used for detection of terminal alkyne-tagged biomolecules via a copper-catalyzed click reaction (CuAAC).
- $90
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Cy5-N3
Sulfo-Cyanine5-azide
T189421621101-43-6
CY5-N3 (Sulfo-Cyanine5-azide) is an anthocyanin fluorescent dye with azide groups, utilized for cell imaging, tissue imaging, and in vivo imaging.
- $112
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Sulfo-Cy5-TCO
T810612129525-69-3
Sulfo-Cy5-TCO is a water-soluble fluorescent dye and click chemistry reagent with the ability to detect tetrazine groups by having a TCO group.
- $392
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7-Azido-4-methylcoumarin
7-azido-4-methyl-2H-chromen-2-one;
T3700095633-27-5
7-Azido-4-methylcoumarin (7-azido-4-methyl-2H-chromen-2-one) is a fluorescent photoactive probe used in the study of human phenol sulfotransferase (SULT1A1 or P-PST-1) substrate binding sites through photoaffinity labeling.
- $31
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DBCO-Cy3
DBCO-Sulfo-Cy3
T189691782950-79-1
DBCO-Cy3 (DBCO-Sulfo-Cy3) is a modified cyanine-3 and orange-red fluorescent dye that can undergo SPAAC click chemistry reactions with azide groups. It has an excitation wavelength of 555 nm and an emission wavelength of 580 nm.
- $169
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Sudan IV
Solvent Red 24, C.I. 26105
TN236485-83-6
Sudan IV (Solvent Red 24) is a lysochrome (fat-soluble dye) diazo dye used for the staining of triglycerides,lipids and lipoproteins on frozen paraffin sections.
- $40
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6-FAM-PEG3-Azide
T83267412319-45-0
6-FAM-PEG3-Azide is a fluorescent dye for labeling oligonucleotides, whose azide group undergoes click chemistry reactions with molecules containing alkyne, DBCO, or BCN groups.
- $66
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CY5-YNE
Sulfo-Cyanine5-alkyne
T189501345823-20-2
CY5-YNE is a CY5-derived dye. CY5 is an amine-reactive fluorophore with excitation/emission wavelengths of 650/670 nm, commonly used for labelling nucleic acids and proteins.
- $74
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BDP TMR tetrazine
T201927
BDP TMR tetrazine is an orange fluorescent dye featuring a terminal tetrazine group.
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Cy3-PEG-DBCO (MW 5000)
T204727
Cy3-PEG-DBCO (MW 5000) is a fluorescent probe containing the Cy3 dye. It features a clickable functional group, DBCO, and PEG, enabling strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with molecules that have azide groups.
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Cy3-PEG-N3 (MW 2000)
T205294
Cy3-PEG-N3 (MW 2000) is a Cy3 azide fluorescent dye designed for labeling amino groups in peptides, proteins, and oligonucleotides. This compound acts as a click chemistry reagent, featuring an azide group that can partake in a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that have DBCO or BCN groups.
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BDP 558/568 DBCO
BDP558/568 DBCO, BDP 558/568DBCO
T202005
BDP 558/568 DBCO is a yellow dye featuring a terminal DBCO group.
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QUN01200
QUN-01200, QUN 01200, Fluorne Rhodamine Picolyl Azide, BP-28125
T202136
QUN01200, also known as Fluorne Rhodamine Picolyl Azide, is a fluorescent probe that contains a pyridine group and a terminal azide group. This compound currently lacks an official name, so the code name has been provisionally assigned according to the MedKoo Chemical Nomenclature (see website: https://www.medkoo.com/page/naming).
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Cy5.5-N3
T204759
Cy5.5-N3, a Cy5.5-azide, is a fluorescent dye employed in cell imaging through click chemistry. It contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules containing alkyne groups. Additionally, it participates in strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules possessing DBCO or BCN groups.
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JUN01107
BP-25560, BP Fluor 546 DBCO, APDye 546 DBCO
T2026672762752-63-4
BP Fluor 546 DBCO is an azide reaction probe suitable for imaging azide-labeled biomolecules using copper-free click chemistry.
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BDP 650/665 azide
T203566
BDP 650/665 azide is an azide group labeled with BDP 650/665, a BODIPY dye that has a maximum excitation wavelength of 650 nm and a maximum emission wavelength of 665 nm. It is suitable for use in click chemistry.
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PF-Alkyne
PF Alkyne
T33957
PF-Alkyne is a fluorophosphonate-based probe which specifically and covalently reacts with the tyrosine-111 residue of the Schistosoma japonicum GST (sjGST) tag. PF-Alkyne rapidly and site-selectively immobilizes sjGST fusion proteins.
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Sulfo Cy3(Et)-N3 DIPEA
3H-Indolium, 1-[6-[(3-azidopropyl)amino]-6-oxohexyl]-2-[3-(1-ethyl-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene)-1-propen-1-yl]-3,3-dimethyl-5-sulfo-, inner salt
T207820
Cy3-N3,sulfo Cy3(Et)-N3.DIPEA is a CY3-derived dye. CY3 (Sulfo-Cyanine3) is an amine-reactive cyanine orange dye with an Ex/Em of 550/570 nm, commonly used for fluorescent labelling of proteins and nucleic acids.
- $195
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PEP azide
T871281807521-02-3
PEP azide is a multifunctional dye used in various biological experiments to observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology, and monitor microorganisms. Its applications range from basic scientific research to clinical diagnostics. Additionally, dyes have applications in traditional fields like textile dyeing, and emerging fields such as functional textile processing, food pigments, and dye-sensitized solar cells.
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Janelia Fluor® 549, Azide
JF549, Azide
T82015
Janelia Fluor® 549, Azide (JF549, Azide) is a fluorescent dye with an absorption maximum (λab (max)) of 549 nm and an emission maximum (λem (max)) of 571 nm.
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C.I. Food Yellow 10
Oil Yellow AB, NSC-11228, NSC11228, NSC 11228, BRN 1842536
T3066785-84-7
C.I. Food Yellow 10, also known as Fast Yellow AB or Acid Yellow, is an azo dye used primarily as a food dye that is now delisted in both Europe and USA and is forbidden if used in foods and drinks. Ungraded products supplied by Spectrum are indicative of
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AF488 DBCO ditriethylamine
T89579
AF488 DBCO ditriethylamine is the ditriethylamine salt form of AF488DBCO, which is a fluorescent dye designed to label biomolecules containing azides. DBCO serves as a bioorthogonal partner for azides, allowing for copper-free covalent coupling. AF488 features a bright and photostable green fluorescent group.
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Fl-DIBO
T864321407523-31-2
Fl-DIBO (fluorogenic dibenzocyclooctyne) serves as a selective fluorescent probe with high sensitivity for azide compounds, rapidly forming highly fluorescent products upon reaction. These products showcase a maximum emission wavelength of 469 nm alongside an excitation wavelength of 363 nm. Fl-DIBO is particularly useful for labeling diazo-tagged proteins, maintaining clarity by avoiding detectable background signal interference [1] [2]. As a click chemistry reagent, Fl-DIBO contains an Alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide-containing molecules.
- $1,520
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FAM hydrazide, 6-isomer hydrochloride
T864042183440-65-3
FAM hydrazide, 6-isomer hydrochloride, a hydrazide derivative of fluorescein (FAM), is a xanthene dye from the fluorescein series. It is used for labeling carbonyl compounds, aldehydes, and ketones [1].
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