BODIPY Series

BODIPY 581 591 C11 is a fluorescent radioactive probe used to indicate lipid peroxidation and antioxidant efficacy in model membrane systems and living cells.

BODIPY-Cholesterol (TF-Chol) is a cholesterol analog with a fluorescent BODIPY motif and cellular permeability, and is a novel BODIPY cholesterol probe.BODIPY-Cholesterol can be used to study intracellular sterol uptake and interorganelle sterol flux.

BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with binding affinities of Ki: 14.5 nM for α1a-AR and Ki: 43.3 nM for α1b-AR, used to study subcellular localization differences in α1-adrenoceptor subtypes.

Py-BODIPY-NHS ester is a small molecular dye with strong UV absorption that can be used to label living cells and immobilise cells.

BODIPY 505 515 is a lipophilic fluorescent probe that localises to intracellular liposomes and has been used to label lipid droplets.BODIPY 505 515 has been used in electron microscopy, epifluorescence microscopy, confocal microscopy, and flow cytometry applications for various algal species.

BODIPY-FL (BDP FL acid) is a broad-spectrum and effective fluorescent dye that can be used to label probes or primers and is a compound for the quantitative detection of specific DNA RNA based on fluorescence bursts.BODIPY-FL-labelled monoterpenes can be used to detect Gram-positive and Gram-negative bacteria as characteristic and pathogenic fungi.

8-Phenyl-2,6-dibromo-1,3,5,7-tetramethyl BODIPY can be used in photodynamic therapy.

8-(4-iodophenyl)-1,3,5,7-tetramethyl BODIPY is a novel BODIPY fluorescent dye for the treatment of cytotoxicity.

BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of VHL ligands. BODIPY FL VH032 consists of a derivative of von Hippel-Lindau (VHL) ligand VH 032 and a fluorophore BODIPY FL(with excitation peak at 504 nm and emission peak at 520 nm), joined by a polyethylene glycol (PEG) 4 linker. The BODIPY FL VH032 VHL TR-FRET signal is stable through the 90 - 300 min incubation time, and theTR-FRET binding assay is sensitive, selective and resistant to assay interference. BODIPY FL VH032 also exhibits high VHL affinity in a fluorescence polarization (FP) assay. Excitation maximum ~ 504 nm; emission maximum ~ 520 nm.

BODIPY-TS (also known as Thiol-green 2) is a highly efficient thiol-specific turn-on probe with a fast response. It incorporates a thiosulfonate scaffold as its thiol recognition unit. BODIPY-TS displays excellent selectivity, low detection limit, and quantitative reactivity towards thiols. Moreover, it exhibits low toxicity. Notably, BODIPY-TS exhibits excitation at 490 nm and emission at 515 nm.

BODIPY 493 503 dye is a vividly green fluorescent dye known for its high molar extinction coefficient and fluorescence quantum yield. It exhibits minimal sensitivity to changes in solvent polarity and pH values. The excitation emission wavelengths are 496 508 nm.

8-Chloro-1,3,5,7-tetramethyl BODIPY is a fluorescent dye featuring a boron-dipyrromethene core. This compound has methyl and chlorine atom substituents at specific positions on the pyrrole rings. It exhibits a high fluorescence quantum yield and distinct absorption and emission wavelengths. Ex Em(nm)=500 515.

BODIPY 558 568 carboxylic acid exhibits high quantum yield and extinction coefficient, resulting in bright yellow-red fluorescence. The excitation emission wavelengths are 558 568 nm.

BDP 581 591 NHS ester, a borondipyrromethene dye (Ex=585 nm, Em=594 nm), exhibits a relatively long fluorescence lifetime and significant two-photon excitation cross-section. This compound is applicable in fluorescence polarization analysis, interacts with reactive oxygen species (ROS) to modify fluorescence, and, as an NHS ester derivative, binds to the primary and secondary amine groups of proteins, peptides, and various molecules. Storage instructions highlight the importance of protecting it from light.

8-(4-Nitrophenyl) BODIPY displays specific reactive properties due to its fluoroboron pyrrole structure and the 4-nitrophenyl segment, both of which can engage in various chemical reactions. For instance, under certain conditions, the nitro group can be reduced to an amino group, among other functional groups, while the boron atom and the pyrrole ring in the fluoroboron pyrrole structure can also react with some nucleophiles.

2,6-Diethyl-1,3,5,7-tetramethyl BODIPY exhibits a high fluorescence quantum yield, and its fluorescence intensity and spectral properties remain stable under prolonged light exposure, showing resistance to photobleaching. [Ex Em(nm)=381 533].

BODIPY Isothiocyanate exhibits the characteristic fluorescent properties of BODIPY compounds, typically with a high fluorescence quantum yield and specific absorption and emission wavelengths. These fluorescence qualities offer potential applications in fields like bioimaging and chemical analysis. In biological applications, it can serve as a fluorescent probe that reacts with specific groups (such as amino groups) in biomolecules, enabling the labeling and tracking of these molecules. For instance, in cell imaging, it can specifically label certain structures or biological processes within cells for observation and study using fluorescence microscopy and similar tools.

8-(4-ethynylphenyl)-1,3,5,7-tetramethyl BODIPY is an organic fluorescent dye characterized by an ethynylphenyl group at the 8-position of the boron dipyrromethene (BODIPY) structure and methyl substituents at the 1, 3, 5, and 7 positions. It boasts a high fluorescence quantum yield and specific chemical properties, making it useful for applications such as fluorescence imaging.

BODIPY 493 503 NHS ester is a widely used reagent for conjugating this dye to proteins or antibodies. The NHS ester reacts with primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The resulting BODIPY 493 503 conjugates exhibit bright fluorescence, narrow emission bandwidth, and relatively long excited-state lifetimes, which are suitable for fluorescence polarization assays and two-photon excitation (TPE) microscopy. Ex Em(nm) = 496 508.

Py-BODIPY is a type of fluorescent dye based on the boron-dipyrromethene (BODIPY) structure that incorporates a pyridine (Py) group. The presence of the pyridine group may enhance the dye's ability to interact with biomolecules or other substrates, thereby broadening its application potential in areas such as biological labeling, bioimaging, and chemical sensing. Ex Em(nm)=508 517.

BDP 630 650 amine is a far-red luminescent boron dipyridyl fluorophore (λex=630 nm, λem=650 nm) used for labeling various electrophilic compounds.

8-Carboxy-1,3,5,7-tetramethyl BODIPY exhibits a high fluorescence quantum yield, with absorption and emission wavelengths situated in a specific spectral region, emitting a particular color of fluorescence. It can serve as a fluorescent probe in the field of bioimaging, allowing for the labeling and tracking of biomolecules and cellular structures.

8-(4-Anilino) BODIPY is a compound featuring a para-anilino group attached at the 8-position of a boron-dipyrromethene core. It is characterized by a high fluorescence quantum yield, narrow emission bandwidth, and excellent photostability, making it widely applicable in areas such as biological imaging, chemical analysis, and materials science.

8-(4-hydroxyphenyl)-1,3,5,7-tetramethyl BODIPY is a fluorescent dye molecule based on the boron-dipyrromethene (BODIPY) structure, known for its high fluorescence quantum yield and excellent photostability. When excited by light at specific wavelengths, it emits bright fluorescence. Its fluorescence properties make it widely applicable in fields such as bioimaging, fluorescent labeling, and sensors. Ex Em(nm)=503 512.