Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of eukaryotic chromosomes in most eukaryotes.

Cat. No.	Product name	CAS No.	Purity
T83248	7-Deaza-2′-deoxyguanosine 5′-triphosphate	101515-08-6	98%
T83248	7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value of 11 μM [1].
TN4443	Lipiferolide	41059-80-7	98%
TN4443	Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitor...
T10574	BMVC	627810-06-4	98%
T10574	BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase (...
T13504	360A iodide	737763-37-0	98%
T13504	360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
T10760	Ceramides Mixture	100403-19-8	mixture
T10760	Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle ar...
T5575	Cycloastragenol	78574-94-4	99.98%
T5575	Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus m...
T1416	Zidovudine	30516-87-1	99.91%
T1416	Zidovudine (ZDV) is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in...
T13174	TMPyP4 tosylate	36951-72-1	99.85%
T13174	TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.
T3333	Cyclogalegenin	84605-18-5	99.74%
T3333	Cyclogalegenin (Astramembrangenin) is able to elongate telomeres, resulting in increased lifespan of the animals.
T13115	Telomerase-IN-2	1610878-54-0	99.32%
T13115	Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).
T41290	MST-312	368449-04-1	98.87%
T41290	MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in ...
T6967	RHPS4	390362-78-4	98.59%
T6967	RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.
T3182	L-778123 hydrochloride	253863-00-2	98.51%
T3182	The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
T7409	360A	794458-56-3	98%
T7409	360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
T12009	Telomerase-IN-1	666859-49-0	97.39%
T12009	Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER ov...
T2902	Costunolide	553-21-9	100%
T2902	Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
T7447	Adefovir	106941-25-7	100%
T7447	Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection...
T2380	BIBR 1532	321674-73-1
T2380	BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
T23819	Braco-19 trihydrochloride	1177798-88-7	98%
T23819	Braco-19 trihydrochloride (BRACO19 3HCl) is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inh...