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DNA Damage/DNA Repair Telomerase

Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of eukaryotic chromosomes in most eukaryotes.
Cat No. product name
TN4443 Lipiferolide Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitor...
T10760 Ceramides Mixture Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle ar...
T10574 BMVC BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase ...
T13115 Telomerase-IN-2 Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activi...
T13504 360A iodide 360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
T7447 Adefovir Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infectio...
T7409 360A 360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
T3333 Cycloastragenol Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
T2902 Costunolide Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
T6967 RHPS4 RHPS4 is a potent inhibitor of Telomerase at submicromolar.
T2380 BIBR 1532 BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
T1416 Zidovudine Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the i...
T3182 L-778123 hydrochloride The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
Lipiferolide
TN4443CAS 41059-80-7
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitor...
Ceramides Mixture
T10760CAS 100403-19-8
Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle ar...
BMVC
T10574CAS 627810-06-4
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase ...
Telomerase-IN-2
T13115CAS 1610878-54-0
Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activi...
360A iodide
T13504CAS 737763-37-0
360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
Adefovir
T7447CAS 106941-25-7
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infectio...
360A
T7409CAS 794458-56-3
360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
Cycloastragenol
T3333CAS 84605-18-5
Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
Costunolide
T2902CAS 553-21-9
Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
RHPS4
T6967CAS 390362-78-4
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
BIBR 1532
T2380CAS 321674-73-1
BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
Zidovudine
T1416CAS 30516-87-1
Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the i...
L-778123 hydrochloride
T3182CAS 253863-00-2
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.