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Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of eukaryotic chromosomes in most eukaryotes.
Cat. No. Product name CAS No. Purity Chemical Structure
T12009 Telomerase-IN-1 666859-49-0 98%
Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER ov...
TN4443 Lipiferolide 41059-80-7 98%
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitor...
T23819 Braco-19 trihydrochloride 1177798-88-7 98%
Braco-19 trihydrochloride is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV viru...
T10574 BMVC 627810-06-4 98%
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase (...
T13504 360A iodide 737763-37-0 98%
360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
T10760 Ceramides Mixture 100403-19-8 98%
Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle ar...
T5575 Cycloastragenol 78574-94-4 98%
Astramembrangenin (Cycloastragenol) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloas...
T1416 Zidovudine 30516-87-1 98%
Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the i...
T3333 Cyclogalegenin 84605-18-5 98%
Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
T13115 Telomerase-IN-2 1610878-54-0 98%
Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activity....
T13174 TMPyP4 tosylate 36951-72-1 98%
TMPyP4 tosylate is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.
T41290 MST-312 368449-04-1 98%
MST-312 is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple m...
T6967 RHPS4 390362-78-4 98%
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
T3182 L-778123 hydrochloride 253863-00-2 98%
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
T7409 360A 794458-56-3 98%
360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
T2902 Costunolide 553-21-9 98%
Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
T7447 Adefovir 106941-25-7 98%
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection...
T2380 BIBR 1532 321674-73-1 98%
BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
Telomerase-IN-1
T12009
Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER ov...
Lipiferolide
TN4443
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitor...
Braco-19 trihydrochloride
T23819
Braco-19 trihydrochloride is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV viru...
BMVC
T10574
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase (...
360A iodide
T13504
360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
Ceramides Mixture
T10760
Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle ar...
Cycloastragenol
T5575
Astramembrangenin (Cycloastragenol) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloas...
Zidovudine
T1416
Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the i...
Cyclogalegenin
T3333
Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
Telomerase-IN-2
T13115
Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activity....
TMPyP4 tosylate
T13174
TMPyP4 tosylate is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.
MST-312
T41290
MST-312 is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple m...
RHPS4
T6967
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
L-778123 hydrochloride
T3182
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
360A
T7409
360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
Costunolide
T2902
Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
Adefovir
T7447
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection...
BIBR 1532
T2380
BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).