T12009 |
Telomerase-IN-1
|
666859-49-0
|
98%
|
|
Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER ov...
|
TN4443 |
Lipiferolide
|
41059-80-7
|
98%
|
|
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitor...
|
T23819 |
Braco-19 trihydrochloride
|
1177798-88-7
|
98%
|
|
Braco-19 trihydrochloride is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV viru...
|
T10574 |
BMVC
|
627810-06-4
|
98%
|
|
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase (...
|
T13504 |
360A iodide
|
737763-37-0
|
98%
|
|
360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
|
T10760 |
Ceramides Mixture
|
100403-19-8
|
98%
|
|
Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle ar...
|
T5575 |
Cycloastragenol
|
78574-94-4
|
98%
|
|
Astramembrangenin (Cycloastragenol) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloas...
|
T1416 |
Zidovudine
|
30516-87-1
|
98%
|
|
Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the i...
|
T3333 |
Cyclogalegenin
|
84605-18-5
|
98%
|
|
Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
|
T13115 |
Telomerase-IN-2
|
1610878-54-0
|
98%
|
|
Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activity....
|
T13174 |
TMPyP4 tosylate
|
36951-72-1
|
98%
|
|
TMPyP4 tosylate is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.
|
T41290 |
MST-312
|
368449-04-1
|
98%
|
|
MST-312 is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple m...
|
T6967 |
RHPS4
|
390362-78-4
|
98%
|
|
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
|
T3182 |
L-778123 hydrochloride
|
253863-00-2
|
98%
|
|
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
|
T7409 |
360A
|
794458-56-3
|
98%
|
|
360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
|
T2902 |
Costunolide
|
553-21-9
|
98%
|
|
Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
|
T7447 |
Adefovir
|
106941-25-7
|
98%
|
|
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection...
|
T2380 |
BIBR 1532
|
321674-73-1
|
98%
|
|
BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
|