Cysteine Protease

Cysteine proteases, also known as thiol proteases, are enzymes that degrade proteins. These proteases share a common catalytic mechanism that involves a nucleophilic cysteine thiol in a catalytic triad or dyad.

Cat. No.	Product name	CAS No.	Purity
T10924	Cysteine protease inhibitor-2	612048-23-4	98%
T10924	Cysteine protease inhibitor 2 is a cysteine protease inhibitor extracted from patent US20070032499A1, compound 12. Cysteine protease inhibitor 2 inhibited DCT116...
T11554	Cathepsin Inhibitor 2	1017931-53-1	98%
T11554	Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
TJS2216	Aurantiamide acetate	56121-42-7	98%
TJS2216	Aurantiamide acetate was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally act...
T16106	ML224	1338824-21-7	98%
T16106	ML224 is a selective TSHR inverse agonist. ML224 also inhibits TSH-stimulated cAMP production (IC50 = 2.3 μM).
T12819	S130	1160852-22-1	98%
T12819	S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 µM).It suppresses autophagy flux.
T13705	GLPG2451	2055015-61-5	98%
T13705	GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1...
T12051	MIV-247	1352817-76-5	98%
T12051	MIV-247 is a selective inhibitor of cathepsin S (human, mouse and cynomolgus monkey cathepsin S with Kis of 2.1, 4.2 and 7.5 nM , respectively).
T11846	LHVS	170111-28-1	98%
T11846	LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine proteas...
T13439	(RS)-Butyryltimolol	2320274-78-8	98%
T13439	(RS)-Butyryltimolol is the racemate of Butyryltimolol. Butyryltimolol, an effective prodrug of Timolol, improves the corneal penetration of Timolol [1]. Butyrylt...
T11896	LV-320	2449093-46-1	98%
T11896	LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC 50 of 24.5 μM and a K d of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flu...
T60812	Cathepsin X-IN-1	2418577-51-0	98%
T60812	Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor (IC50= 7.13 µM). Cathepsin X-IN-1 shows inhibition effect to PC-3 cell migration with low cytoto...
T16394	ONO-5334	868273-90-9	98%
T16394	ONO-5334 is an effective and selective cathepsin K inhibitor (Ki: 0.10 nM, 0.049 nM, and 0.85 nM for human, rabbit, and rat cathepsin K, respectively). ONO-5334 ...
T16474	Petesicatib	1252637-35-6	98%
T16474	Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
TP2056L	Acetyl-Calpastatin (184-210)(human) acetate		98%
TP2056L	Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin...
T13288	VBY-825	1310340-58-9	98%
T13288	VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
T60150	(1S,2R)-Alicapistat	2221010-57-5	98%
T60150	(1S,2R)-Alicapistat ((1S,2R)-ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential application of Alzheimer's disease (AD)...
T37753	Aureusimine B	170713-71-0	98%
T37753	Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears t...
T27695	JTE-607	188791-09-5
T27695	JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.
T19503	Papain	9001-73-4
T19503	Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
T2470	MDL-28170	88191-84-8
T2470	Calpain Inhibitor III is a Cysteine protease.