T11554 |
Cathepsin Inhibitor 2
|
1017931-53-1
|
98%
|
|
Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
|
T13439 |
(RS)-Butyryltimolol
|
2320274-78-8
|
98%
|
|
(RS)-Butyryltimolol is the racemate of Butyryltimolol. Butyryltimolol is an effective prodrug of Timolol that improves the corneal penetration of Timolol [1]. Bu...
|
T12819 |
S130
|
1160852-22-1
|
98%
|
|
S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 µM).It suppresses autophagy flux.
|
T11846 |
LHVS
|
170111-28-1
|
98%
|
|
LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine proteas...
|
T16106 |
ML224
|
1338824-21-7
|
98%
|
|
ML224 is a selective TSHR inverse agonist. ML224 also inhibits TSH-stimulated cAMP production (IC50 = 2.3 μM).
|
T16394 |
ONO-5334
|
868273-90-9
|
98%
|
|
ONO-5334 is an effective and selective cathepsin K inhibitor (Ki: 0.10 nM, 0.049 nM, and 0.85 nM for human, rabbit, and rat cathepsin K, respectively). ONO-5334 ...
|
T10924 |
Cysteine protease inhibitor-2
|
612048-23-4
|
98%
|
|
Cysteine protease inhibitor 2 is a cysteine protease inhibitor extracted from patent US20070032499A1, compound 12. Cysteine protease inhibitor 2 inhibited DCT116...
|
T16474 |
Petesicatib
|
1252637-35-6
|
98%
|
|
Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
|
T13705 |
GLPG2451
|
2055015-61-5
|
98%
|
|
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1...
|
T12051 |
MIV-247
|
1352817-76-5
|
98%
|
|
MIV-247 is a selective inhibitor of cathepsin S (human, mouse and cynomolgus monkey cathepsin S with Kis of 2.1, 4.2 and 7.5 nM , respectively).
|
T11896 |
LV-320
|
2449093-46-1
|
98%
|
|
LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC 50 of 24.5 μM and a K d of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flu...
|
T37753 |
Aureusimine B
|
170713-71-0
|
98%
|
|
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears t...
|
T13288 |
VBY-825
|
1310340-58-9
|
98%
|
|
VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
|
T19503 |
Papain
|
9001-73-4
|
98%
|
|
Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
|
T2470 |
MDL-28170
|
88191-84-8
|
98%
|
|
Calpain Inhibitor III is a Cysteine protease.
|
T1080 |
2-Aminoethanethiol
|
60-23-1
|
98%
|
|
Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
|
TP2056L |
Acetyl-Calpastatin (184-210)(human) acetate
|
|
98%
|
|
Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin...
|
T7451 |
2-Cyanopyrimidine
|
14080-23-0
|
98%
|
|
2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM)
|
T3088 |
N-Ethylmaleimide
|
128-53-0
|
98%
|
|
N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies.
|
T2493 |
PD 151746
|
179461-52-0
|
98%
|
|
PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0...
|