thymidine

Thymidine (DThyd) is a cell synchronizing agent and a specific precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis and can cause cell cycle arrest in the G1/S phase.

Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chromosome fragmentation.

5-deoxy Thymidine (5'-Deoxythymidine) is a thymidine form which 5' position replaced with hydrogen.5'-deoxy Thymidine was effective against the activity of Bacillus subtilis and Staphylococcus aureus.

Thymidine-5'-diphosphate-L-rhamnose disodium, isolated from Occhromonas malhamensis [1], is a chemical compound.

Thymidine-5'-monophosphate disodium salt (Standard) is the standard substance of Thymidine-5'-monophosphate disodium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chromosome fragmentation.

Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and reverse transcriptase.

Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and thymidine respectively), or deoxyribose-containing deoxynucleosides, and their corresponding ribonucleotides or deoxyribonucleotides. Pyrimidines serve essential functions in human metabolism as ribonucleotide bases in RNA (uracil and cytosine), and as deoxyribonucleotide bases in DNA (cytosine and thymine), and are linked by phosphodiester bridges to purine nucleotides in double-stranded DNA, in both the nucleus and the mitochondria. Pyrimidine activated sugars are also involved in polysaccharide and phospholipid synthesis, glucuronidation in detoxification processes, glycosylation of proteins and lipids and in the recently identified novel endothelium-derived vasoactive dinucleotides.

Folitixorin (ANX-510) is an active folate derivative and coenzyme associated with thymidine synthesis, with potential antitumour activity.

Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating the p21 protein and ultimately pro

Enamidonin is a lipopeptide antibiotic. It inhibits EGF-dependent [3H] thymidine incorporation in Balb/MK cells with an IC50 of 10 μg/mL and can restore the transformed SRCTS-NRK cells to their normal flat shape with an ED50 of 10 μg/mL. It exhibits no antibacterial activity.

Pilatin exhibits inhibitory effects on both bacteria and fungi, and it strongly suppresses the incorporation of thymidine and uridine into DNA and RNA in Ehrlich ascites tumor cells.

Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity against clinical strains of Mycobacterium tuberculosis.

Actiketal is an antibiotic from the glutarimide class that can inhibit the incorporation of [3H] thymidine in EGF-stimulated Balb MK cells.