dg 1

DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing the expression of CD26, ET-1, FGF-1, and EGF. Additionally, it notably inhibits cancer tissue proliferation in the A549 xenograft mouse model [1].

15:0-18:1 DG is a form of diacylglycerol (DAG). It is produced by the hydrolysis of triacylglycerol (TAG) found in butter. This compound shows potential for research in obesity, cardiovascular diseases, and dietary interventions.

18:1-12:0 Biotin DG is a biotinylated lipid.

16:0-18:1 DG Glucose is a glycosylated diacylglycerol.

S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.

Chloro(2-dicyclohexylphosphino-2',6'-diisopropoxy-1,1-biphenyl)[2-(2-aminoethylphenyl)]palladium(II) 2-methoxy-2-methylpropane complex is a useful organic compound for research related to life sciences and the catalog number is T64624.

Chloro(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)[2-(2-aminoethylphenyl)]palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T64659.

[2-[2-(Amino-κN)ethyl]phenyl-κC][bis(1,1-dimethylethyl)[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]chloropalladium is a useful organic compound for research related to life sciences and the catalog number is T66450.

DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).

1-Oleoyl-2-linoleoyl-rac-glycerol (DG(18:1/0:0/18:2)) is a diacylglycerol composed of linoleic acid and oleic acid. This compound can be found in dry-cured ham and acts as a flavoring agent in food.

MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.

ALN29882 is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage. 18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay. It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay. It is suitable to use in lipid-protein overlay screen assay with the recombinant protein His-AtROP6.

1-Stearoyl-2-docosahexaenoyl-sn-glycerol (18:0-22:6 DG) is a diacylglycerol capable of binding to RasGRP and modulating the activation of MAP kinases.

3'-DMTr-dG(iBu) is a nucleoside used in the synthesis of nucleic acids, including antiviral agents for researching viral infections (HBV, HDV) and oligonucleotides aimed at combating Alzheimer's disease and other tauopathies [1].

Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].

1-Palmitoyl-3-arachidoyl-rac-glycerol is a diacylglycerol featuring palmitic acid at the sn-1 position and arachidic acid at the sn-3 position.

1-Linoleoyl-3-palmitoyl-rac-glycerol, a diacylglycerol, is characterized by the presence of linoleic acid (at the sn-1 position) and palmitic acid (at the sn-3 position). This compound has been detected in wheat bran extracts and in dry-cured Iberian ham, but not in its raw form.

1,3-Dinervonoyl glycerol, a diacylglycerol, features nervonic acid at the sn-1 and sn-3 positions.

1-Myristoyl-3-elaidoyl-rac-glycerol is a diacylglycerol comprising myristic acid and elaidic acid at the sn-1 and sn-3 positions, respectively.

1-Linoleoyl-3-α-linolenoyl-rac-glycerol, a diacylglycerol, features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position. This compound is identified in olive oil that has undergone lipase-catalyzed glycerolysis, utilizing immobilized lipase B derived from C. antarctica.

1-Stearoyl-3-arachidoyl-rac-glycerol is a diacylglycerol with stearic acid at the sn-1 position and arachidic acid at the sn-3 position.

"1-Lauroyl-2-palmitoyl-rac-glycerol is a diacylglycerol featuring lauric acid (at the sn-1 position) and palmitic acid (at the sn-2 position)."

1-Palmitoyl-3-stearoyl-rac-glycerol, a diacylglycerol, features palmitic acid at the sn-1 position and stearic acid at the sn-3 position. This compound appears in palm-based diacylglycerols derived from palm stearin, palm mid fraction, palm oil, and palm olein, as well as in extracts of wheat bran and brewer's spent grain.

1-Myristoyl-3-palmitoyl-rac-glycerol, a diacylglycerol, features myristic acid at the \(sn\)-1 position and palmitic acid at the \(sn\)-3 position.