ctx

CTX1 is a small molecule activator of p53.

CTX-0294885, a novel bisanilino pyrimidine, exhibits inhibitory activity against a broad range of kinases in vitro and is further developed into a Sepharose-supported kinase capture reagent.

CTX-471 is a fully humanized monoclonal antibody targeting CD137, exhibiting agonistic activity and binding affinity (Kd=50/61/748 nM) to recombinant human, cynomolgus monkey, and mouse CD137. It enhances T cell and natural killer cell activation, making it suitable for studying immunomodulation and cancer.

Cardiotoxin Analog (CTX) IV (6-12) TFA, a partial peptide of Cardiotoxin Analog IV, is derived from the venom of the Taiwan Cobra, showcasing the unique properties of snake venom cardiotoxin.

Cardiotoxin Analog (CTX) IV (6-12) is a peptide fragment of Cardiotoxin Analog (CTX) IV, isolated from the venom of the Taiwan Cobra (Naja atra).

CTX-0294885 hydrochloride is an agarose-supported kinase capture reagent.

CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.

BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.

Avibactam sodium (NXL-104) is a non-β-lactam β-lactamase inhibitor that inhibits TEM-1, P99, and KPC-2 β-lactamases (IC50=8/80/38 nM) covalently and reversibly. Avibactam sodium has antimicrobial activity and can be used to treat urinary tract infections.

Avibactam free acid is a potent β-lactamase inhibitor exhibiting covalent and reversible properties, capable of inhibiting TEM-1, P99, and CTX-M-15 at nanomolar concentrations. Avibactam free acid and Ceftazidime may be combined for treating urinary tract infections.

CCR4 antagonist 2 (Compound 31) is a novel, potent, orally bioavailable small molecule antagonist of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. CCR4 antagonist 2 (Compound 31) exhibits IC50 values of Ca2+ flux and [chemotaxis] CTX at 40 nM and 70 nM, respectively.

alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.

Acebilustat (CTX-4430) (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor.

FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. It inhibited PBP2 with an IC50 of 3.2 μM and has a high level of antibacterial and considerable antimicrobial activity.

PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.

CTX-712 is a potent inhibitor of cdc2-like kinase (CLK), effectively reducing cancer cell growth and survival.

CTX-0294885 hydrochloride is a broad-spectrum kinase inhibitor capable of capturing 235 kinases from MDA-MB-231 cells, including all members of the AKT family. This compound serves as a potent tool for analyzing kinome signaling networks and holds potential for research into diseases such as inflammation, diabetes, and cancer.

CTX-2026, a fully human antibody, targets and binds to CD277, demonstrating an anti-tumor effect in ovarian tumor models, and is utilized in cancer research [1].

CTX-1211 is a selective and orally active melanocortin 4 receptor (MC4R) agonist with an EC50 of 0.38 nM. It enhances the effects of liraglutide in suppressing food intake and promoting weight loss, supporting anorectic and weight-reducing activities. CTX-1211 is primarily employed in research related to obesity and other metabolic disorders.

Ciguatoxin CTX 3C is a hapten that can rapidly disrupt neuronal excitability balance.

Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.

Endo-1,4-β-xylanase (Xylanase), a glycoside hydrolase enzyme that degrades arabinoxylan (AX), is commonly utilized in biochemical research. It specifically hydrolyzes the β-xylosidic bonds linking two d-xylopyranosyl residues in a β-(1,4) configuration [1].

Avibactam sodium hydrate (NXL-104 hydrate) is a highly effective β-lactamase inhibitor that inhibits β-lactamases TEM-1 and CTX-M-15, as well as the carbapenemase produced by Klebsiella pneumoniae and carbapenem-resistant Enterobacteriaceae.

ω-Hexatoxin-Hv1a, a neurotoxin extracted from the venom of the spider Hadronyche versuta, inhibits voltage-gated calcium channels [1] [2].