a-121

A 121 is a non-polyene antifungal antibiotic. It is active against a number of filamentous fungi including some plant and human pathogens.

A-1211212 (BCL2-IN-1) is a potent and selective Bcl-2 inhibitor. It promotes lymphocyte apoptosis, alters colonic mucosa in mice, and improves inflammation.

SKA-121 is a selective KCa3.1 activator (EC50s: 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively).

A-1210477-piperazinyl is a compound that specifically targets and binds to the protein myeloid cell leukemia 1 (MCL1) [myeloid cell leukemia 1]. This compound is utilized in PROTAC technology, harnessing the ability to selectively degrade target proteins.

A-1210477 is an effective and specific MCL-1 and Bcl-2 inhibitor (Ki/IC50: 0.454/26.2 nM).

ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels.

Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.

Bevacizumab, a humanized monoclonal antibody, specifically and with high affinity binds to all isoforms of VEGF-A.

ADTL-SA1215 is a selective SIRT3 activator with SIRT3 deacetylase activity that inhibits the proliferation and migration of human breast cancer MDA-MB-231 cells through the SIRT3-driven autophagy/mitochondrial autophagy signaling pathway, and can be used in the study of triple negative breast cancer.

MDL-104168 is a macrocyclic HIV-protease inhibitor.

Ociperlimab (BGB-A1217) is a humanized antibody targeting TIGIT with antitumor activity. It blocks the TIGIT-PVR interaction and is used in the study of advanced solid tumors.

Anti-IL-12 p70 Antibody (20C2) is an anti-human IL-12 p70 monoclonal antibody of the IgG1 isotype, and it acts by suppressing the production of interferon-gamma. Anti-IL-12 p70 Antibody (20C2) is applicable for research studies investigating inflammatory conditions where IL-12 signaling contributes to disease pathogenesis. Anti-IL-12 p70 Antibody (20C2) is recommended to be paired with an appropriate isotype control, specifically Rat IgG1 kappa, Isotype Control.

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) is an IgG2a, κ inhibitory antibody derived from mice, specifically targeting murine CD40L/CD154.

Anti-Mouse Jagged 2 Antibody (HMJ2-1) is an IgG antibody inhibitor derived from American hamster, specifically targeting mouse Jagged 2.

Anti-MouseIL-12Antibody (R1-5D9) is an IgG2a antibody inhibitor derived from rats, designed to target and inhibit mouse IL-12.

Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) is an IgG1 antibody inhibitor derived from mice, specifically targeting rat FcRn heavy chain heterodimers.

Anti-Mouse CD73 Antibody (TY/23) is an IgG2a, κ antibody inhibitor derived from rats, targeting mouse CD73.

Anti-Mouse MAdCAM-1 Antibody (MECA-367) is a rat-derived IgG2a, κ antibody inhibitor targeting mouse MAdCAM-1.

Anti-Canine CD34 Antibody (1H6) is an IgG1, κ antibody inhibitor derived from mice and targets canine CD34.

Anti-Mouse GITR (D265A) Antibody (DTA-1) targets the mouse GITR.

Anti-Mouse CD16/CD32 (LALA-PG) Antibody (2.4G2) is an IgG2a, κ inhibitor antibody derived from mice and targets mouse CD16/CD32.

Anti-Rat CD8α Antibody (OX-8) is an IgG1, κ antibody inhibitor derived from mice, designed to target and inhibit rat CD8α.

Secretin (33-59), rat (TFA) is a 27-aa peptide, which acts on secretin receptor, and enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas[1][2].

Protein Kinase C (19-31) TFA, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate p