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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9116 | SMCC | N-Succinimidyl 4-(N-maleimidomethyl)cycl | Others |
SMCC (N-Succinimidyl 4-(N-maleimidomethyl)cycl) is a heterobifunctional protein crosslinker. | |||
T16899 | SMCC-DM1 | DM1-SMCC | Others |
SMCC-DM1 (DM1-SMCC) (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC). | |||
T18728 | Sulfo-SMCC sodium | Others | |
Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable i... | |||
T11917 | Lys-SMCC-DM1 | Lys-Nε-MCC-DM1 | Microtubule Associated |
DM1 is a tubulin inhibitor. Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is the active metabolite of DM1. | |||
T33865 | Palbociclib-SMCC | PD0332991-SMCC,Palbociclib-SMCC linker,PD 0332991-SMCC,PD-0332991-SMCC | |
Palbociclib-SMCC is a Palbociclib derivative with a SMCC linker. | |||
T28289 | Paclitaxel-SMCC | SMCC taxol, Taxol-SMCC, Taxol SMCC,Paclitaxel with SMCC linker,SMCC-Taxol,Paclitaxel ADC conjugate. | |
Paclitaxel-SMCC is a paclitaxel derivative with a SMCC linker. (Succinimidyl-4-( N -maleimidomethyl)cyclohexane-1-carboxylate). Paclitaxel-SMCC can be used to synthesize Paclitaxel bioconjugates with enzymes, antobodies,... | |||
T18361 | MMAE-SMCC | Others | |
MMAE-SMCC is a drug-linker conjugate designed for antibody-drug conjugates (ADC). It consists of MMAE, a potent inhibitor of mitosis and tubulin, and SMCC, a linker that facilitates the development of ADCs. | |||
T17833 | DM4-SMCC | Others | |
DM4-SMCC, a non-cleavable drug-linker conjugate for antibody-drug conjugates (ADC), leverages the antitumor efficacy of DM4 (an antitubulin agent) through attachment with the SMCC linker, exhibiting antitumor activity[1]... | |||
T15161 | Doxorubicin-SMCC | Others | |
Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T18856 | Trans-Sulfo-SMCC | Others | |
trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker. | |||
T81280 | Rha-PEG3-SMCC | ||
Rha-PEG3-SMCC (Compound 13) serves as an ADC (antibody-drug conjugate) linkage agent with robust antitumor properties, utilizing the protein crosslinker SMCC, which is tethered through the non-cleavable linker Rha-PEG3. | |||
T16251 | N-Succinimidyl-S-acetylthioacetate | SATA | Others |
N-Succinimidyl-S-acetylthioacetate (SATA) is a protein modification agent that introduces thiol-groups into protein molecules and adds sulfhydryl groups in a protected form to proteins and other amine-containing molecule... | |||
T41026 | Biotin-LC-LC-NHS | ||
Biotin-LC-LC-NHS is a SMCC cross-linking reagent, which serves as a labeling agent for antibodies and small molecules, like Paclitaxel. | |||
T17834 | DM4-SPDP | Others | |
DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amin... |