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Golgi apparatus

Golgi dyes are a class of chemical reagents specifically used to label and observe the Golgi apparatus in cells. They can specifically bind to specific molecules or structural components in the Golgi apparatus. Through imaging techniques such as fluorescence microscopy, these dyes can help study the function and location of the Golgi apparatus and its role in the cell secretory pathway.

  • Mgc(3Me)DEAC
    T868942763442-02-8
    Mgc(3Me)DEAC (compound mgc3MeDEAC) is a small-molecule fluorescent probe that allows for the visualization of the Golgi apparatus in living cells [1].
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  • Mgc(3Me)FDA
    T868952763442-01-7
    Mgc(3Me)FDA, a derivative of fluorescein diacetate (FDA) that incorporates a cell-permeable myrGC 3Me motif, effectively penetrates cells. Once inside, it transforms into the fluorescently active mgc(3Me)FL. This compound specifically accumulates in the Golgi apparatus, serving as a visualized Golgi probe [1].
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  • AIE-GA
    T856092653341-16-1
    AIE-GA is a fluorescent probe for the Golgi apparatus (GA) that operates in the green channel with an excitation wavelength of 405 nm and an emission range of 500-700 nm. It exhibits a strong binding affinity to interact with COX-2 by binding to its cyclooxygenase catalytic site [1].
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    • Gol-NTR
      T82272
      Gol-NTR, a highly selective and sensitive Golgi-targetable probe, is activated by Nitroreductase (NTR) to visualize acute lung injury (ALI) and its repair. With a low detection limit of 54.8 ng mL, Gol-NTR is well-suited for research focused on monitoring and assessing the response of sepsis-induced ALI [1].
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    • BODIPY FL C5-Ceramide
      T87517133867-53-5
      BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye used to visualize individual cells, with excitation emission wavelengths at 505 nm 512 nm. The Golgi fluorescent probe, a BODIPY-labeled ceramide derivative, is synthesized in the endoplasmic reticulum and transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, enabling specific labeling of the dye [1][2].
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