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Endoplasmic reticulum

Endoplasmic reticulum dyes are a class of chemical reagents used to label and observe the structure of the endoplasmic reticulum in cells. They can specifically bind to lipid or protein components on the endoplasmic reticulum membrane. Through imaging techniques such as fluorescence microscopy, these dyes can help study the function and morphology of the endoplasmic reticulum and its role in protein synthesis and secretion.

  • ER Flipper-TR 28
    T863802334078-37-2
    ER Flipper-TR 28, a small molecule fluorophore flipper probe, enables imaging of membrane tension within the endoplasmic reticulum (ER). This compound is characterized by a pentafluorophenyl group and reacts with protein thiolate on the cytoplasm-facing surface of the ER [1].
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    3-6 months
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  • ER-Tracker Blue-White DPX
    T86383287715-95-1
    ER-Tracker dye, a derivative of BODIPY series dyes coupled with Glibenclamide, exhibits high selectivity for the endoplasmic reticulum and is non-toxic to cells at low concentrations. This environmentally sensitive probe retains part of its fluorescence after formaldehyde treatment and features high fluorescence life and a good extinction coefficient. Glibenclamide, an ATP-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker, binds in the endoplasmic reticulum. However, ER-Tracker is not suitable for staining cells after fixation [1].
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    3-6 months
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  • AIE-ER
    T856082653341-17-2
    AIE-ER is a specialized fluorescent probe for the endoplasmic reticulum (ER) that operates in the green channel with excitation at λ ex =405 nm and emission between λ em =450~650 nm. It is notable for its exceptional photostability, high brightness, and low working concentration, potentially facilitating research into ER-related diseases [1].
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