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Immunology and Inflammation Disease Modeling Immunology and Inflammation Disease ModelingExperimental autoimmune encephalomyelitis Modeling
Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for studying multiple sclerosis (MS). It is induced in mice or rats by immunization with myelin-associated antigens such as myelin oligodendrocyte glycoprotein (MOG) or myelin basic protein (MBP), triggering immune-mediated inflammation in the central nervous system. The EAE model is valuable for investigating neuroimmune regulation, myelin repair, and anti-inflammatory immunotherapies.
MOG peptide (35-55), mouse, rat acetate
Cited
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate, MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base)
T7657L
MOG peptide (35-55), mouse, rat acetate, is a minor component of central nervous system myelin with encephalitogenic activity. It can induce CD4⁺ T cell proliferation and Th1-type immune responses, leading to relapsing-remitting demyelinating disease. It is commonly used to establish experimental autoimmune encephalomyelitis (EAE) models.
- $135
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QTY
CitedMOG (35-55) mouse, rat
MOG (35-55)
T7657149635-73-4
MOG (35-55) mouse, rat is a minor component of the central nervous system myelin with high brain specificity and strong immunogenicity. It can induce T and B cell responses, trigger relapsing-remitting neurological disorders with plaque-like demyelination, and is commonly used for inducing experimental autoimmune encephalomyelitis (EAE) models.
- $56
Size
QTY
PLP (190-209)
TP2616165549-59-7
PLP (190-209) is a peptide derived from proteolipid protein (PLP) and is widely used to induce experimental autoimmune encephalomyelitis (EAE) animal models.
- Inquiry Price
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QTY
MOG (35-55) TFA
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA, MOG (35-55) (TFA)
TP1091
MOG (35-55) TFA is a minor component of central nervous system myelin with encephalitogenic activity. It can induce T cell proliferation, activate Th1 cytokine responses, and elicit high levels of IgG antibodies, leading to relapsing-remitting central nervous system disease characterized by extensive plaque-like demyelination. It is commonly used to induce experimental autoimmune encephalomyelitis (EAE) models.
- $121
Size
QTY
Arachidonic acid sodium salt
Immunocytophyt sodium salt
T845446610-25-9
Arachidonic acid sodium salt is a polyunsaturated omega-6 fatty acid that is a major component of biological membranes, serving as a substrate for various lipid mediators including prostaglandins (PG). It can improve cognitive responses and cardiovascular function, and can also be used to induce paw swelling models.
- $171
Size
QTY
PLP (139-151)
PLP 139-151
TP1282131334-43-5
PLP (139-151) is an amino acid fragment from positions 139 to 151 of myelin proteolipid protein (PLP), which is used to induce the relapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE) model.
- $85
Size
QTY
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