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Experimental autoimmune encephalomyelitis Modeling
Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for studying multiple sclerosis (MS). It is induced in mice or rats by immunization with myelin-associated antigens such as myelin oligodendrocyte glycoprotein (MOG) or myelin basic protein (MBP), triggering immune-mediated inflammation in the central nervous system. The EAE model is valuable for investigating neuroimmune regulation, myelin repair, and anti-inflammatory immunotherapies.
Arachidonic acid
Cited
T4129506-32-1
Arachidonic acid (Immunocytophyte) is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.
- $39
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Citedκ-Carrageenan
T3849911114-20-8
κ-Carrageenan, a natural polymer found predominantly in red seaweeds, can serve as an effective drug carrier for delivering curcumin to cancer cells and inducing apoptosis. Additionally, κ-Carrageenan holds promise as a potential inflammatory agent, amplifying existing intestinal inflammation.
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Arachidonic acid sodium salt
T845446610-25-9
Arachidonic acid sodium salt (Immunocytophyt), a polyunsaturated omega-6 fatty acid, is a key component of biomembranes and serves as a substrate for different lipid mediators, like prostaglandins (PGs). It enhances cognitive and cardiovascular functions [1].
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