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Cystitis Modeling

Cystitis is inflammation of the bladder mucosa caused by infection or irritation, with bacterial cystitis being the most commonly studied form. Common models include Escherichia coli injection or instillation, cyclophosphamide-induced cystitis, and multi-stimulus combined models. These are widely used to investigate immune responses, inflammatory pathways, and analgesic drug screening.

Cyclophosphamide
T0707L50-18-0
Cyclophosphamide is an alkylating agent type of anti-tumor drug, and its main target is DNA. Cyclophosphamide inhibits the proliferation of tumor cells by undergoing alkylation reactions with DNA, interfering with the replication and transcription processes of DNA.
  • $35
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Cyclophosphamide hydrate
Cyclophosphamide monohydrate
T07076055-19-2
Cyclophosphamide hydrate is a synthetic alkylating agent structurally related to nitrogen mustards, with antitumor and immunosuppressive activities. It is widely used in the treatment of various cancers and is also commonly employed to induce animal models of premature ovarian failure, myelosuppression, cystitis, and myocarditis.
  • $33
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TargetMol | Citations Cited
Protamine sulfate
T410319009-65-8
Protamine sulfate is a polycationic peptide compound with anti-heparin activity. It can neutralize the anticoagulant effects of heparin, enhance lipid-mediated gene transfer, and is commonly used to establish cystitis models.
  • $30
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