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Myocarditis Modeling

Myocarditis is an inflammatory condition of the myocardium, often caused by viral infection, autoimmune responses, or drug toxicity. Commonly used experimental models include coxsackievirus B3 (CVB3) infection, autoimmune antigen induction, and drug-induced models (e.g., isoproterenol). These models are instrumental in evaluating immune-mediated myocardial injury, immune regulation mechanisms, and the efficacy of cardioprotective therapies.

Resiquimod
T6964144875-48-9
Resiquimod (R848) is an agonist of Toll-like receptors 7 and 8 (TLR7/TLR8) that induces the upregulation of cytokines including TNF-α, IL-6, and IFN-α. It possesses immunomodulatory, antitumor, and antiviral activities, and can be used to induce models of myocarditis and systemic lupus erythematosus (SLE).
  • $30
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Myosin H Chain Fragment, mouse acetate
T80046
Myosin H Chain Fragment, mouse acetate salt is a peptide segment derived from the α-myosin heavy chain and is used to induce experimental autoimmune myocarditis (EAM) in mice.
  • $98
7-10 days
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Myosin H Chain Fragment, mouse
T78375
MyosinH Chain Fragment, mouse is a fragment derived from the α-myosin heavy chain peptide and can be used to induce experimental autoimmune myocarditis (EAM) in mouse models.
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