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Psoriasis Modeling
Psoriasis is a chronic immune-mediated skin disorder characterized by epidermal hyperproliferation, inflammatory infiltration, and abnormal keratinization. Commonly used mouse models include imiquimod (IMQ)-induced models, IL-23 injection, and transgenic approaches. These models are widely applied to evaluate cytokine networks, the Th17/IL-23 signaling axis, and the efficacy of small-molecule targeted therapies.
Imiquimod hydrochloride
T2209199011-78-6
Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].
- $33
Size
QTY
CitedImiquimod maleate
T22862896106-16-4
Imiquimod maleate (R 837 maleate) is a toll-like receptor 7 (TLR7) agonist and immune response modifier with antiviral and antitumor effects. Imiquimod maleate induces psoriatic-like skin lesions in mice and can be used to study various skin malignancies.
- $29
Size
QTY
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