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Pancreatitis Modeling

Pancreatitis, including both acute and chronic forms, involves complex pathogenic mechanisms such as premature activation of pancreatic enzymes, release of inflammatory cytokines, and oxidative stress. Commonly used animal models include L-arginine induction, bile duct ligation, and alcohol-induced methods. These models are valuable for investigating pancreatic tissue injury mechanisms, evaluating anti-inflammatory therapies, and exploring intervention strategies for multiple organ dysfunction.

Ceruletide
T1493217650-98-5
Ceruletide is a decapeptide that is a safe and effective cholecystokinin and cholecystokinin receptor agonist with direct spasmodic effects on the gallbladder muscle and bile duct.[1]
  • $109
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Taurocholic acid
TN225981-24-3
Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathway.
  • $55
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L-Arginine
T3S036474-79-3
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate lymphocyte proliferation through an interleukin-2-independent pathway. 4. A combination of oral L-citrulline and L-Arginine effectively and rapidly augments NO-dependent responses at the acute stage.
  • $31
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Sodium taurocholate
TWA2417145-42-6
Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid.[3] These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.
  • $50
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Taurocholic acid sodium salt hydrate
T1138345909-26-4
Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate), formed by the conjugation of taurine with cholic acid, is the primary ingredient in the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is employed as a cholagogue and choleretic.
  • $42
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L-Arginine hydrochloride
T06701119-34-2
L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide.
  • $48
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