T41163 |
ZNL 02-096
|
2414418-49-6
|
99.84%
|
|
ZNL 02-096 (Pomalidomide-C3-adavosertib) is a rapid and selective degrader of Wee1 (IC50=3.58 nM).ZNL 02-096 selectively degrades Wee1 at submolar concentrations...
|
T9643 |
ZN-c3
|
2376146-48-2
|
99.8%
|
|
ZN-c3 is a potent and selective Wee1 inhibitor with balanced potency, ADME, and pharmacokinetic properties.
|
T6931 |
PD0166285
|
185039-89-8
|
99.59%
|
|
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.
|
T2077 |
Adavosertib
|
955365-80-7
|
99.58%
|
|
Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.
|
T9864 |
Debio-0123
|
2243882-74-6
|
99.52%
|
|
Debio-0123 (WEE1-IN-5) is a potent, orally available and highly specific WEE1 inhibitor with an IC 50 in the low nanomolar range. Debio-0123 inhibits phospho-CDC...
|
T60889 |
RP-6306
|
2719793-90-3
|
99.28%
|
|
RP-6306 is a potent, selective and orally active PKMYT1 inhibitor (IC50= 14 nM). RP-6306 exhibits a high degree of selectivity for PKMYT1 over other kinases in c...
|
T8916 |
WEE1-IN-3
|
2272976-28-8
|
98.61%
|
|
WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.
|
T9966 |
GSK-1520489A
|
1042433-41-9
|
98%
|
|
GSK-1520489A is an active PKMYT1 inhibitor.
|
T16446 |
PD 407824
|
622864-54-4
|
98%
|
|
PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkp...
|