T6526 |
GW791343 trihydrochloride
|
309712-55-8
|
98%
|
|
GW791343 HCl is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
|
T16399 |
Opiranserin
|
1441000-45-8
|
98%
|
|
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is...
|
T9653 |
(E/Z)-Sivopixant
|
1640808-39-4
|
98%
|
|
(E/Z)-Sivopixantis a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.
|
T20731 |
Brilliant blue G-250
|
6104-58-1
|
98%
|
|
Brilliant Blue G is an antagonist of the P2X7 purinergic receptor.
|
T14920 |
CE-224535
|
724424-43-5
|
98%
|
|
CE-224535 is a selective antagonist of P2X7 receptor. CE-224535 can be used in disease-modifying antirheumatic studies.
|
T9786 |
Lu AF27139
|
2097117-06-9
|
98%
|
|
Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and ra...
|
T40045 |
Sivopixant
|
2414285-40-6
|
98%
|
|
Sivopixant (S-600918) is a potent and selective antagonist of P2X3 receptor (P2X3 IC 50 =4.2 nM; P2X2/3 IC 50 =1100 nM). Sivopixant shows strong analgesic effect...
|
T10207 |
A 438079
|
899507-36-9
|
98%
|
|
A 438079 is a potent, and selective antagonist of P2X7 receptor (pIC50: 6.9).
|
T9833 |
Opiranserin hydrochloride
|
1440796-75-7
|
98%
|
|
Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, ...
|
TP2226 |
BzATP triethylammonium salt
|
112898-15-4
|
|
|
BzATP triethylammonium salt is a P2X7 receptor agonist.
|
T8333 |
Aurintricarboxylic acid
|
4431-00-9
|
|
|
Aurintricarboxylic acid is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing ...
|
T37806 |
JNJ-55308942
|
2166558-11-6
|
100%
|
|
JNJ-55308942 is a selective and brain-penetrant antagonist of P2X7 functional with IC50s of 10 and 15 nM and Kis of 7.1 and 2.9 nM for hP2X7 and rP2X7, respectiv...
|
T7881 |
CTP disodium dihydrate
|
81012-87-5
|
100%
|
|
CTP disodium dihydrate is an agonist of P2X4 purinergic receptor
|
T2806 |
Lappaconitine
|
32854-75-4
|
92.57%
|
|
Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
|
T7805 |
GW791343 dihydrochloride
|
1019779-04-4
|
95.57%
|
|
GW791343 dihydrochloride is a P2X7 allosteric modulator.
|
TQ0002 |
A-317491
|
475205-49-3
|
96.1%
|
|
A-317491 is a non-nucleotide P2X3 ( Ki: 22 nM) and P2X2/3 receptor (Ki: 9 nM) antagonist, which inhibits calcium flux mediated by the receptors.
|
T1131 |
Ivermectin
|
70288-86-7
|
97.74%
|
|
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
|
T8946 |
Indophagolin
|
1207660-00-1
|
97.84%
|
|
Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and ...
|
T2087 |
AF-353
|
865305-30-2
|
97.95%
|
|
AF-353, an effective and orally bioavailable antagonist of the P2X3/P2X2/3 receptor, inhibits human and rat P2X3 (pIC50= 8.0).
|
T4S0536 |
Bullatine A
|
1354-84-3
|
98%
|
|
1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the treat...
|